Echocardiography Findings and Perioperative Outcomes in Children
1 other identifier
observational
400
1 country
1
Brief Summary
This study evaluates the association between perioperative echocardiographic Doppler findings and clinical outcomes in pediatric patients undergoing cardiac surgery. In our center, anesthesiologists perform transthoracic or transesophageal echocardiography during perioperative period routinely in children undergoing surgery for congenital cardiac disease. Echocardiographic findings include the doppler patterns of hepatic vein, portal vein, renal artery, renal vein and splenic vein before and after cardiopulmonary bypass. Portal pulsatility index, renal resistive index, and respiratory variations in peak aortic blood flow velocity and diameter of inferior vena cava are measured.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 14, 2019
CompletedFirst Posted
Study publicly available on registry
June 19, 2019
CompletedStudy Start
First participant enrolled
June 24, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2021
CompletedMay 5, 2022
May 1, 2022
2.5 years
June 14, 2019
May 3, 2022
Conditions
Outcome Measures
Primary Outcomes (2)
Characteristics of Doppler values and its derived parameters of portal vein, hepatic vein, renal artery and vein, and splenic vein measured using echocardiography in children with congenital cardiac disease
To find the characteristics and standard values of Doppler findings measured by echocardiography before and after congenital cardiac surgery
after anesthetic induction until the end of surgery
Association between Doppler values measured by echocardiography and clinical outcomes after pediatric cardiac surgery
To evaluate whether Doppler values of portal vein, hepatic vein, renal artery and vein, and splenic vein measured using echocardiography can predict major adverse outcomes after pediatric cardiac surgery
through study completion, an average 1-2 years
Secondary Outcomes (1)
Number of patients with major adverse outcomes after pediatric cardiac surgery
through study completion, an average 1-2 years
Study Arms (1)
Children with congenital cardiac disease
Children with congenital cardiac disease who undergoing surgery
Interventions
Echocardiographic examination before and after cardiopulmonary bypass
Eligibility Criteria
Pediatric patients undergoing cardiac surgery
You may qualify if:
- All pediatric patients undergoing cardiac surgery
You may not qualify if:
- Applying extracorporeal membrane oxygenator prior to surgery
- Trouble applying echocardiography
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Seoul National University Hospital
Seoul, 03080, South Korea
Related Publications (1)
Lee JH, Denault AY, Beaubien-Souligny W, Kang P, Kim J, Kim HW, Ji SH, Jang YE, Kim EH, Kim HS, Kim JT. Higher portal venous pulsatility is associated with worse clinical outcomes following congenital heart surgery: a single-centre prospective cohort study. Can J Anaesth. 2023 Dec;70(12):1957-1969. doi: 10.1007/s12630-023-02605-0. Epub 2023 Nov 2.
PMID: 37919629DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
June 14, 2019
First Posted
June 19, 2019
Study Start
June 24, 2019
Primary Completion
December 30, 2021
Study Completion
December 30, 2021
Last Updated
May 5, 2022
Record last verified: 2022-05