Role of Echocardiography in Pulmonary Embolism

NCT04020250 | Unknown

• 1 other identifier: Echo in Pulmonary Embolism
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.To analyze the diagnostic and prognostic value of echocardiographic parameters.
2. 2.Prediction of APE-related 30-day mortality and adverse out comes.
3. 3.The need for rescue thrombolysis in initially normotensive Acute pulmonary embolism (APE) patients.

Conditions

Pulmonary Embolism

Outcome Measures

Primary Outcomes (1)

• the need for rescue thrombolysis in initially normotensive Acute pulmonary embolism patients.

  analyses the diagnostic and prognostic value of a new echocardiographic parameter, TRPG/ TAPSE, for prediction of APE-related 30-day death or the need for rescue thrombolysis in initially normotensive Acute pulmonary embolism patients.

  one month

Interventions

Echocardiography DEVICE

Echocardiographic parameters: Tricuspid annulus plane systolic excursion (TAPSE) Tricuspid regurgitation peak gradient (TRPG)

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients diagnosed with pulmonary embolism confirmed by contrast-enhanced multidetector computed tomography (MDCT) when thrombo-emboli were visualized

You may qualify if:

• Age \>18 and \<70 years.
• Patients with intermediate- risk pulmonary embolism will be
• hemodynamically stable at admission with systolic blood pressure
• mmHg and without signs of peripheral hypoperfusion.
• \- elevated cardiac biomarkers levels (particularly, a positive cardiac troponin test

You may not qualify if:

• Age \<18 years.
• Patients diagnosed with chronic thromboembolic hypertension.
• Patients with valvular heart diseases.
• Patients with lung cancer.
• Acute massive pulmonary embolism.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Bernard S, Namasivayam M, Dudzinski DM. Reflections on Echocardiography in Pulmonary Embolism-Literally and Figuratively. J Am Soc Echocardiogr. 2019 Jul;32(7):807-810. doi: 10.1016/j.echo.2019.05.007. No abstract available.

  PMID: 31272591 BACKGROUND

• Kanar BG, Sahin A, Gol G, Ogur E, Kavas M, Atas H, Mutlu B. Timing and magnitude of regional right ventricular function and their relationship with early hospital mortality in patients with acute pulmonary embolism. Anatol J Cardiol. 2019 Jun;22(1):26-32. doi: 10.14744/AnatolJCardiol.2019.38906.

  PMID: 31264657 BACKGROUND

• Kanar BG, Gol G, Ogur E, Kavas M, Atas H, Mutlu B. Assessment of right ventricular function and relation to mortality after acute pulmonary embolism: A speckle tracking echocardiography-based study. Echocardiography. 2019 Jul;36(7):1298-1305. doi: 10.1111/echo.14398. Epub 2019 Jun 11.

  PMID: 31184782 BACKGROUND

MeSH Terms

Conditions

Pulmonary Embolism

Interventions

Echocardiography

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Cardiac Imaging Techniques; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Ultrasonography; Heart Function Tests; Diagnostic Techniques, Cardiovascular

Central Study Contacts

Rofaida Raafat, MBBch

CONTACT

01099646399; rofaidaraafatchest@gmail.com

Maha Elkholy, Professor

CONTACT

01096956205; maha_elkholy@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: July 9, 2019
• First Posted: July 16, 2019
• Study Start: August 1, 2019
• Primary Completion: August 1, 2020
• Study Completion: September 1, 2020
• Last Updated: July 16, 2019

Record last verified: 2019-07