NCT03917901

Brief Summary

The proposed study will design and evaluate a computerized-delivered single-session anxiety sensitivity reduction program (i.e., Anxiety Sensitivity Training; AST). The AST will be designed to achieve three primary aims: (1) provide psycho-educational information on AS and its consequences, (2) present psycho-educational information on the relationship between AS and obesity-related health behavior correlates, and (3) offer concrete, evidence-based strategies to facilitate motivation to change their obesity-related lifestyle behaviors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
131

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Sep 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 13, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 17, 2019

Completed
5 months until next milestone

Study Start

First participant enrolled

September 16, 2019

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 6, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 6, 2021

Completed
3.5 years until next milestone

Results Posted

Study results publicly available

August 26, 2024

Completed
Last Updated

August 26, 2024

Status Verified

July 1, 2024

Enrollment Period

1.5 years

First QC Date

April 13, 2019

Results QC Date

July 8, 2022

Last Update Submit

July 31, 2024

Conditions

Keywords

Anxiety DisordersDepressionAnxiety SensitivityObesityEatingPhysical ActivityExercise

Outcome Measures

Primary Outcomes (4)

  • Anxiety Sensitivity Index-3

    The Anxiety Sensitivity Index-3 is an 18-item measured that will be used to assess sensitivity to, and fear of, the potential negative consequences of anxiety-related symptoms and sensations. Items are rated on a 5-point Likert scale, ranging from 0 (Very Little) to 4 (Very Much). Scores will be calculated by summing all items (possible range = 0 -72), with lower scores indicating a better outcome.

    Baseline,1-week, 2-week and 1-month follow-up

  • Dutch Eating Behavior Questionnaire

    The Dutch Eating Behavior Questionnaire will be used to assess emotional eating. Items are rated on a 5-point Likert scale ranging from 1 (never) to 5 (very often). For the current study, the emotional eating subscale (13 items) will be used as a measure of emotional eating. The 13 items of the subscale are summed and divided by 13 to create a mean score with a range from 1-5. Lower scores on this measure indicate better outcomes.

    Baseline,1-week, 2-week and 1-month follow-up

  • Eating Expectancy Inventory

    The Eating Expectancy Inventory will be used to measure cognitive expectancies of eating. The Eating Expectancy Inventory subscale facet: eating helps manage negative affect will be used in the current study. Respondents will be asked to rate on a 7-point Likert scale the degree to which they 1 (completely disagree) to 7 (completely agree) to each item. Responses are summed for each subscale. Lower scores on the 18-item eating helps manage negative affect subscale (possible range = 18 - 126) indicate better outcomes.

    Baseline,1-week, 2-week and 1-month follow-up

  • Exercise Self-Efficacy

    Exercise self-efficacy will be assessed with a 5-item self-report assessment of one's confidence about their ability to engage in physical activity. Items are rated on a 9-point Likert-type scale that ranges from 0 (not at all confident) to 8 (extremely confident). A total score will be created by summing the 5-items with higher scores indicating a better outcome (possible range 0 - 40).

    Baseline,1-week, 2-week and 1-month follow-up

Study Arms (2)

Anxiety Sensitivity Training

EXPERIMENTAL

The Anxiety Sensitivity training (AST) will provide: (1) psychoeducation on anxiety sensitivity and its consequences, (2) psychoeducation on the relationship between anxiety sensitivity and obesity-related health behavior correlates, and (3) concrete, evidenced-based strategies to reduce anxiety sensitivity.

Other: Anxiety Sensitivity Training

Health Control

PLACEBO COMPARATOR

The Health Control (HC) will cover general health care, such as information on wearing sunscreen and regular attendance to doctor appointments. The HC will not provide any recommendations or education on mood, dietary, or physical habits.

Other: Health Control

Interventions

Computerized Single-Session Anxiety Sensitivity Reduction Program

Anxiety Sensitivity Training

Computerized Single-Session Health Information Control

Health Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have a body mass index of at least 30
  • Endorse elevated anxiety sensitivity defined as an ASI-3 score of 17 or greater

You may not qualify if:

  • Any anticipated matters that would interfere with participating in the study
  • Not being fluent in English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Anxiety and Health Research Lab, Substance Use Treatment Clinic, University of Houston

Houston, Texas, 77204, United States

Location

Related Links

MeSH Terms

Conditions

ObesityMotor ActivityAnxiety DisordersDepression

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehaviorMental DisordersBehavioral Symptoms

Results Point of Contact

Title
Brooke Kauffman
Organization
University of Houston

Study Officials

  • Brooke Kauffman, MA

    University of Houston

    PRINCIPAL INVESTIGATOR
  • Michael J Zvolensky, Ph.D.

    University of Houston

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: If participant meets eligibility criteria, the participant will be randomly assigned to complete a one-session computer-delivered intervention: either (1) anxiety sensitivity reduction treatment or (2) health information control.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 13, 2019

First Posted

April 17, 2019

Study Start

September 16, 2019

Primary Completion

March 6, 2021

Study Completion

March 6, 2021

Last Updated

August 26, 2024

Results First Posted

August 26, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations