NCT03907384

Brief Summary

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2018

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 26, 2019

Completed
14 days until next milestone

First Posted

Study publicly available on registry

April 9, 2019

Completed
Last Updated

October 30, 2020

Status Verified

October 1, 2020

Enrollment Period

7 months

First QC Date

March 26, 2019

Last Update Submit

October 29, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Arterial Stiffness

    via Pulse Wave Velocity

    12 weeks

Secondary Outcomes (3)

  • Systolic and Diastolic Blood Pressure

    12 weeks

  • Pressure Wave Reflection

    12 weeks

  • Endothelial Function

    12 weeks

Study Arms (2)

Mat Pilates training

EXPERIMENTAL

The MPT group participated in 3-one hour supervised training sessions per week for 12 weeks. All MP sessions were performed in nonconsecutive days. The MP sessions were divided into the following stages: initial warm up and stretching (10 min), general conditioning consisting of MP exercises (40 min) and stretching and cooling down (10 min). The participants performed 12 basic MP exercises (one set of 6-10 repetitions was performed per exercise). Breathing, a core principle of MP, was performed by forced but controlled inspirations and exhalations, while relaxing and contracting the abdomen, respectively. All sessions were supervised by a certified MP instructor.

Behavioral: Mat Pilates training

Control

NO INTERVENTION

Participants in the non-exercising control group did not participate in a supervised exercise program and visited the laboratory at the same frequency as participants in the swim intervention and underwent recreational activities such as board games

Interventions

This group completed 12-weeks of training

Mat Pilates training

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • body mass index 30-40 kg/m2
  • \<1 h of regular exercise per week in the previous year
  • systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP
  • Nonsmokers

You may not qualify if:

  • body mass index ˂30 and ≥40 kg/m2
  • chronic diseases
  • taking oral contraceptives
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Nebraska

Omaha, Nebraska, 68022, United States

Location

Related Publications (1)

  • Wong A, Figueroa A, Fischer SM, Bagheri R, Park SY. The Effects of Mat Pilates Training on Vascular Function and Body Fatness in Obese Young Women With Elevated Blood Pressure. Am J Hypertens. 2020 May 21;33(6):563-569. doi: 10.1093/ajh/hpaa026.

MeSH Terms

Conditions

ObesityHypertension

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 26, 2019

First Posted

April 9, 2019

Study Start

April 1, 2018

Primary Completion

October 30, 2018

Study Completion

October 30, 2018

Last Updated

October 30, 2020

Record last verified: 2020-10

Locations