NCT03110393

Brief Summary

The aim of this study is the randomized comparison of two laryngeal mask (Intersurgical i-gel® and Ambu®AuraGain™) in obese patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2017

Completed
23 days until next milestone

First Posted

Study publicly available on registry

April 12, 2017

Completed
8 days until next milestone

Study Start

First participant enrolled

April 20, 2017

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 6, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 6, 2017

Completed
Last Updated

January 8, 2018

Status Verified

January 1, 2018

Enrollment Period

5 months

First QC Date

March 20, 2017

Last Update Submit

January 5, 2018

Conditions

Keywords

ObeseLaryngeal Mask AirwayAnaesthesia

Outcome Measures

Primary Outcomes (1)

  • Time of successful intubation

    Measurement of a fiberoptic intubation with the laryngeal mask. Start: Insertion of the fiberoptic into the larynxmask until the intubation has been done and after the fiberoptic has been removed.

    intraoperative

Secondary Outcomes (22)

  • Number of Insertions (of the laryngeal mask)

    intraoperative

  • Time of insertion

    intraoperative

  • Number of insertion attempts

    intraoperative

  • Gastric volume

    intraoperative

  • Positioning of the gastric probe

    intraoperative

  • +17 more secondary outcomes

Study Arms (2)

Ambu® AuraGain™

EXPERIMENTAL

Intervention with Ambu® AuraGain™Laryngeal Mask

Device: Ambu AuraGain

Intersurgical i-gel®

ACTIVE COMPARATOR

Intervention with Intersurgical i-gel® Laryngeal Mask

Device: Intersurgical i-gel

Interventions

Insert and intubation of an Ambu® AuraGain™ laryngeal mask

Ambu® AuraGain™

Insert and intubation of an Intersurgical i-gel®

Intersurgical i-gel®

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ASA 1-3
  • Shoulder-/Elbow-/Hip-/Knee- or Foot - Surgery
  • Signed informed consent
  • BMI \> 35kg/m2

You may not qualify if:

  • Non-sober patients (last meal \<6 h)
  • Symptomatic reflux disease
  • Hiatus hernia
  • Significant cardiovascular risk factors
  • Severe COPD
  • Gastric band or gastric bypass
  • Disease which allows an accurate examination of the physicians (e.g. neuromuscular, mental, metabolic disease)
  • Drug or drug abuse in the recent past
  • Legal immaturity (incompetence)
  • Acute disease, which calls into question the narcotic potential
  • Patients with whom the use of a laryngeal mask is contraindicated or otherwise not possible

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Schulthess Klinik

Zurich, 8008, Switzerland

Location

Related Publications (1)

  • Moser B, Keller C, Audige L, Dave MH, Bruppacher HR. Fiberoptic intubation of severely obese patients through supraglottic airway: A prospective, randomized trial of the Ambu(R) AuraGain laryngeal mask vs the i-gel airway. Acta Anaesthesiol Scand. 2019 Feb;63(2):187-194. doi: 10.1111/aas.13242. Epub 2018 Aug 8.

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Berthold Berthold, MD

    Schulthess Klinik

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 20, 2017

First Posted

April 12, 2017

Study Start

April 20, 2017

Primary Completion

September 6, 2017

Study Completion

September 6, 2017

Last Updated

January 8, 2018

Record last verified: 2018-01

Data Sharing

IPD Sharing
Will not share

Locations