Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
VESALIUS-CV
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
3 other identifiers
interventional
12,301
31 countries
826
Brief Summary
This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Jun 2019
Longer than P75 for phase_3
826 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 11, 2019
CompletedFirst Posted
Study publicly available on registry
March 13, 2019
CompletedStudy Start
First participant enrolled
June 11, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 25, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
July 25, 2025
CompletedNovember 10, 2025
November 1, 2025
6.1 years
March 11, 2019
November 7, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Time to Coronary Heart Disease Death, Myocardial Infarction, or Ischemic Stroke
Time to coronary heart disease (CHD) death, myocardial infarction (MI), or ischemic stroke, whichever occurs first.
From randomization; for approximately a median of 4.5 years
Time to Coronary Heart Disease Death, Myocardial Infarction, Ischemic Stroke, or Any Ischemia-driven Arterial Stroke
Time to CHD death, MI, ischemic stroke, or any ischemia-driven arterial revascularization, whichever occurs first.
From randomization; for approximately a median of 4.5 years
Secondary Outcomes (10)
Time to MI, Ischemic Stroke, or Any Ischemia-driven Arterial Revascularization
From randomization; for approximately a median of 4.5 years
Time to CHD Death, MI, or Any Ischemia-driven Arterial Revascularization
From randomization; for approximately a median of 4.5 years
Time to Cardiovascular Death, MI, or Ischemic Stroke
From randomization; for approximately a median of 4.5 years
Time to CHD Death or MI
From randomization; for approximately a median of 4.5 years
Time to Myocardial Infarction
From randomization; for approximately a median of 4.5 years
- +5 more secondary outcomes
Study Arms (2)
Placebo
PLACEBO COMPARATORParticipants will receive placebo subcutaneous injection once every 2 weeks (Q2W).
Evolocumab 140 mg Q2W
EXPERIMENTALParticipants will receive 140 mg evolocumab by subcutaneous injection Q2W.
Interventions
Administered subcutaneously using an autoinjector pen.
Eligibility Criteria
You may qualify if:
- Age: Adult participants ≥ 50 (men) or ≥ 55 (women) to ˂ 80 years of age (either sex) and meeting lipid criteria.
- Lipid Criteria: Low-density lipoprotein cholesterol (LDL-C) ≥ 90 mg/dL (≥ 2.3 mmol/L) or non high-density lipoprotein cholesterol (non-HDL)-C ≥ 120 mg/dL (≥ 3.1 mmol/L), or apolipoprotein B ≥ 80 mg/dL (≥ 1.56 µmol/L).
- Diagnostic evidence of at least one of the following (A-D) at screening:
- A.Significant coronary artery disease (CAD) meeting at least 1 of the following criteria:
- History of coronary revascularization with multi-vessel coronary disease as evidenced by any of the following:
- percutaneous coronary intervention (PCI) of 2 or more vessels, including branch arteries,
- PCI or coronary artery bypass grafting (CABG) with residual 50% stenosis in a separate, unrevascularized vessel, or
- multi-vessel CABG 5 years or more prior to screening.
- Significant coronary disease without prior revascularization as evidenced by either a ≥70% stenosis of at least 1 coronary artery, ≥50% stenosis of 2 or more coronary arteries, or ≥50% stenosis of the left main coronary artery.
- known coronary artery calcium score ≥100 in participants without a coronary artery revascularization prior to randomization.
- B. Significant atherosclerotic cerebrovascular disease meeting at least 1 of the following criteria:
- prior transient ischemic attack with ≥50% carotid stenosis.
- internal or external carotid artery stenosis of ≥70% or 2 or more ≥50% stenoses.
- prior internal or external carotid artery revascularization.
- C. Significant peripheral arterial disease meeting at least 1 of the following criteria:
- +20 more criteria
You may not qualify if:
- MI or stroke prior to randomization.
- CABG ˂ 3 months prior to screening.
- eGFR ˂ 15 mL/min/1.73 m\^2.
- Uncontrolled or recurrent ventricular tachycardia in the absence of an implantable-cardioverter defibrillator.
- Atrial fibrillation or atrial flutter not on anticoagulation therapy (vitamin K antagonist, heparin, low molecular weight heparin, fondaparinux,or non-Vitamin K antagonist oral anticoagulant).
- Triglycerides ≥ 500 mg/dL (5.7 mmol/L) measured up to 3 months prior to screening. The most recent results must be used.
- Last measured left-ventricular ejection fraction ˂ 30% or New York Heart Association (NYHA) Functional Class III/IV.
- Planned arterial revascularization.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Amgenlead
Study Sites (852)
North Alabama Research Center LLC
Athens, Alabama, 35611, United States
Cardiovascular Associates
Birmingham, Alabama, 35243, United States
Heart Center Research LLC
Huntsville, Alabama, 35801, United States
Mobile Heart Specialists PC
Mobile, Alabama, 36608, United States
Arkansas Cardiology
Little Rock, Arkansas, 72205, United States
Central Arkansas Veterans Healthcare System
Little Rock, Arkansas, 72205, United States
Cardiovascular Research Foundation of Southern California
Beverly Hills, California, 90210, United States
Westside Medical Associates of Los Angeles
Beverly Hills, California, 90211, United States
West Coast Research LLC
Dublin, California, 94568, United States
Desert Oasis Healthcare Medical Group
Palm Springs, California, 92262, United States
Covigilant Research, LLC
Riverside, California, 92506, United States
Sierra Clinical Research
Roseville, California, 95661, United States
Center for Clinical Trials of Sacramento Inc
Sacramento, California, 95823, United States
Harbor University of California Los Angeles Medical Center
Torrance, California, 90502, United States
Optumcare Colorado Springs LLC
Colorado Springs, Colorado, 80906, United States
University of Colorado Memorial Health System
Colorado Springs, Colorado, 80909, United States
New West Physicians
Golden, Colorado, 80401, United States
South Denver Cardiology Associates
Littleton, Colorado, 80120, United States
Cardiology Associates of Fairfield County, PC
Stamford, Connecticut, 06905, United States
Excel Medical Clinical Trials
Boca Raton, Florida, 33434, United States
Bay Area Cardiology
Brandon, Florida, 33511, United States
Nature Coast Clinical Research LLC
Crystal River, Florida, 34429, United States
Daytona Heart Group
Daytona Beach, Florida, 32114, United States
Cardiology Research Associates
Daytona Beach, Florida, 32117, United States
Complete Health Research
DeLand, Florida, 32720, United States
Cohen Medical Associates PA
Delray Beach, Florida, 33446, United States
Jellinger and Lerman MD PA dba The Center for Diabetes and Endocrine Care
Fort Lauderdale, Florida, 33312, United States
George E Platt MD
Green Cove Springs, Florida, 32043, United States
Research Physicians Network Alliance
Hollywood, Florida, 33021, United States
University of Florida and Shands Hospital
Jacksonville, Florida, 32209, United States
Jacksonville Center for Clinical Research
Jacksonville, Florida, 32216, United States
First Coast Cardiovascular Institute PA
Jacksonville, Florida, 32256, United States
Baptist Health Research Institute
Jacksonville Beach, Florida, 32250, United States
Gad Research Center
Miami, Florida, 33155, United States
Cardiovascular Research Center of South Florida
Miami, Florida, 33173, United States
Ocala Research Institute, Inc
Ocala, Florida, 34471, United States
Cardiology Consultants
Pensacola, Florida, 32501, United States
Charlotte Heart Group Research Center
Port Charlotte, Florida, 33952, United States
Intercoastal Medical Group
Sarasota, Florida, 34232, United States
Cardiovascular Center of Sarasota
Sarasota, Florida, 34239, United States
Florida Cardiology Group
Winter Park, Florida, 32792, United States
The Florida Lipid Institute
Winter Park, Florida, 32792, United States
NSC Research
Johns Creek, Georgia, 30024, United States
Kootenai Heart Clinics, LLC
Coeur d'Alene, Idaho, 83814, United States
Northwest Heart Clinical Research LLC
Arlington Heights, Illinois, 60005, United States
Deaconess Clinic
Evansville, Indiana, 47713, United States
LaPorte County Institute for Clinical Research
Michigan City, Indiana, 46360, United States
Midwest Cardiovascular Research Foundation
Davenport, Iowa, 52801, United States
The University of Iowa College of Public Health
Iowa City, Iowa, 52242, United States
MercyOne Iowa Heart Center
West Des Moines, Iowa, 50266, United States
The University of Kansas Medical Center
Kansas City, Kansas, 66160-7601, United States
Saint Elizabeth Covington
Covington, Kentucky, 41011, United States
The Research Group of Lexington LLC
Lexington, Kentucky, 40503, United States
Alexandria Cardiology Clinic
Alexandria, Louisiana, 71301, United States
Grace Research LLC
Bossier City, Louisiana, 71111, United States
Horizon Research Group of Opelousas LLC
Eunice, Louisiana, 70535, United States
Louisiana Heart Center
Hammond, Louisiana, 70403, United States
Barnum Medical Research
Natchitoches, Louisiana, 71457, United States
Grace Research LLC
Shreveport, Louisiana, 71105, United States
Louisiana Heart Center
Slidell, Louisiana, 70458, United States
Northern Light Eastern Maine Medical Center
Bangor, Maine, 04401, United States
Southern Maine Health Care
Biddeford, Maine, 04005, United States
Maryland Cardiovascular Specialists
Baltimore, Maryland, 21229, United States
Metropolitan Cardiovascular Consultants LLC
Beltsville, Maryland, 20705, United States
TidalHealth Peninsula Regional, Inc
Salisbury, Maryland, 21804, United States
Brigham and Womens Hospital
Boston, Massachusetts, 02215, United States
Charles River Medical Associates
Framingham, Massachusetts, 01701, United States
East Mountain Medical Associates, PC
Great Barrington, Massachusetts, 01230, United States
Baystate Health Center
Springfield, Massachusetts, 01199, United States
Ahmed Arif Medical Research Center LLC
Flint, Michigan, 48504, United States
Healthy Heart Cardiology
Grand Rapids, Michigan, 49546, United States
Rajendra H Mehta, MD, PC
Jackson, Michigan, 49201, United States
Munson Medical Center
Traverse City, Michigan, 49684, United States
Saint Marys Medical Center
Duluth, Minnesota, 55805, United States
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, 55407, United States
Saint Cloud Hospital
Saint Cloud, Minnesota, 56303, United States
HealthEast Medical Research Institute
Saint Paul, Minnesota, 55102, United States
Kansas City Veterans Affairs Medical Center
Kansas City, Missouri, 64128, United States
Mercy Research
St Louis, Missouri, 63141, United States
Great Falls Clinic LLP
Great Falls, Montana, 59405, United States
Bryan Heart
Lincoln, Nebraska, 68506, United States
Nebraska Western Iowa Health Care System
Omaha, Nebraska, 68105, United States
Palm Research Center Inc
Las Vegas, Nevada, 89128, United States
Virtua Health, Inc.
Voorhees Township, New Jersey, 08043, United States
Healthwise Medical Associates
Brooklyn, New York, 11206, United States
Trinity Medical Western New York, PC
Cheektowaga, New York, 14227, United States
WMCHealth Heart and Vascular Institute Kingston Division of Cardiology
Kingston, New York, 12401, United States
Northwell Health Physician Partners Cardiology
Manhasset, New York, 11030, United States
North Shore Diabetes and Endocrine Associates
New Hyde Park, New York, 11042, United States
Northwell Health Lenox Hill Heart and Vascular
New York, New York, 10022, United States
Hudson Valley Cardiovascular Physicians PC
Poughkeepsie, New York, 12601, United States
Saratoga Clinical Research, LLC
Saratoga Springs, New York, 12866, United States
Division of Cardiovascular Research at Peconic Bay Medical Center
Southampton, New York, 11968, United States
Asheville Cardiology Associates
Asheville, North Carolina, 28803, United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
Novant Health Heart and Vascular Institute
Charlotte, North Carolina, 28204, United States
Moses H Cone Memorial Hospital
Greensboro, North Carolina, 27401, United States
Crossroads Clinical Research Inc
Mooresville, North Carolina, 28117, United States
Piedmont Medical Group Research of Rocky Mount
Rocky Mount, North Carolina, 27804, United States
PMG Research of Salisbury
Salisbury, North Carolina, 28144, United States
Novant Health Forsyth Medical Center
Winston-Salem, North Carolina, 27103, United States
Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
Lillestol Research LLC
Fargo, North Dakota, 58104, United States
The Christ Hospital
Cincinnati, Ohio, 45219, United States
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
North Ohio Heart Center
Elyria, Ohio, 44035, United States
Sanjay Vora Research LLC
Marion, Ohio, 43302, United States
North Ohio Heart Center-Sandusky
Sandusky, Ohio, 44870, United States
Heart House Research Foundation
Springfield, Ohio, 45504, United States
Intend Research
Norman, Oklahoma, 73069, United States
Oklahoma Heart Institute
Tulsa, Oklahoma, 74133, United States
Oregon Health and Science University
Portland, Oregon, 97239, United States
Capital Area Research LLC
Camp Hill, Pennsylvania, 17011, United States
Geisinger Holy Spirit
Camp Hill, Pennsylvania, 17011, United States
Doylestown Health Cardiology
Doylestown, Pennsylvania, 18901, United States
Lycoming Internal Medicine Inc
Jersey Shore, Pennsylvania, 17740, United States
Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, 19104, United States
Cardiology Consultants of Philadelphia CCP
Philadelphia, Pennsylvania, 19107, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Miriam Hospital
Providence, Rhode Island, 02906, United States
Pharmacorp Clinical Trials Inc
Charleston, South Carolina, 29412, United States
Piedmont Research Partners
Fort Mill, South Carolina, 29707, United States
Tribe Clinical Research LLC DBA Mountain View Clinical Research
Greenville, South Carolina, 29607, United States
Main Street Physicians Care Waterway
Little River, South Carolina, 29566, United States
The Diabetes Center
Murrells Inlet, South Carolina, 29576, United States
Palmetto Clinical Research
Summerville, South Carolina, 29485, United States
Monument Health Clinical Research
Rapid City, South Dakota, 57701, United States
Parkway Cardiology Associates
Oak Ridge, Tennessee, 37830, United States
Soltero Cardiovascular Research Center
Dallas, Texas, 75226, United States
Southwest Family Medicine Associates
Dallas, Texas, 75235, United States
Humble Cardiology Associates
Kingwood, Texas, 77339, United States
Texas Cardiology Associates of Houston
Kingwood, Texas, 77339, United States
Texas Institute for Kidney and Endocrine Disorders
Lufkin, Texas, 75904, United States
Texas Institute of Cardiology
McKinney, Texas, 75071, United States
Southern Endocrinology Associates PA
Mesquite, Texas, 75149, United States
Permian Research Foundation
Odessa, Texas, 79761, United States
South Texas Cardiovascular Consultants PLLC
San Antonio, Texas, 78201, United States
Mercury Medical Conversions LTD
San Antonio, Texas, 78229, United States
Northwest Houston Heart Center
Tomball, Texas, 77375, United States
Alpine Research Organization
Farmington, Utah, 84025, United States
Suffolk Multispecialty Research LLC
Suffolk, Virginia, 23435, United States
Selma Medical Associates
Winchester, Virginia, 22601, United States
Multicare Institute for Research and Innovation
Puyallup, Washington, 98372, United States
Universal Research Group LLC
Tacoma, Washington, 98405, United States
Aspirus Research Institute
Wausau, Wisconsin, 54401, United States
Instituto de Investigaciones Clinicas Bahia Blanca
Bahía Blanca, Buenos Aires, B8000FTD, Argentina
Stat Research
CABA, Buenos Aires, C1023AAB, Argentina
Cinme - Centro de Investigaciones Metabolicas
CABA, Buenos Aires, C1027AAP, Argentina
Ciprec - Centro de Investigacion y Prevencion Cardiovascular
CABA, Buenos Aires, C1119ACN, Argentina
Consultorio Medico Dr Litvak Bruno
CABA, Buenos Aires, C1406BOA, Argentina
Centro de Especialidades Medicas - Cemedic
CABA, Buenos Aires, C1407GTN, Argentina
Centro Medico Laura Maffei
CABA, Buenos Aires, C1425AGC, Argentina
Cardiología Palermo
CABA, Buenos Aires, C1425BNG, Argentina
Cedic - Centro de Investigacion Clinica
CABA, Buenos Aires, C1425DES, Argentina
Centro Medico Dra De Salvo
CABA, Buenos Aires, C1426ABP, Argentina
Fundacion Respirar
CABA, Buenos Aires, C1426ABP, Argentina
Instituto de Investigaciones Metabolicas - Idim
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1012AAR, Argentina
Hospital Universitario Fundacion Favaloro
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1093AAS, Argentina
Icba - Instituto Cardiovascular de Buenos Aires
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1428ART, Argentina
Glenny Corp SA
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1430CKE, Argentina
Instituto de Investigaciones Clinicas Mar del Plata
Mar del Plata, Buenos Aires, B7600FZN, Argentina
Ciad - Consultorio Integral de Atencion al Diabetico
Morón, Buenos Aires, B1708EPE, Argentina
Dim Clinica Privada
Ramos Mejía, Buenos Aires, B1704ETD, Argentina
Instituto de Investigaciones Clinicas de San Nicolas
San Nicolás de los Arroyos, Buenos Aires, B2900DMH, Argentina
Instituto de Investigaciones Clinicas Zarate
Zárate, Buenos Aires, B2800DGH, Argentina
Clinica Privada del Prado
Córdoba, Córdoba Province, 5000, Argentina
Clinica Fusavim Privada SRL
Villa María, Córdoba Province, X5900JKA, Argentina
Sanatorio Santa Rosa Srl
Santa Rosa, La Pampa Province, 6300, Argentina
Instituto de Investigaciones Clínicas Rosario-Sanatorio Delta
Rosario, Santa Fe Province, 2000, Argentina
Sanatorio Plaza
Rosario, Santa Fe Province, 2000, Argentina
Centro Modelo de Cardiologia
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Clinical Mayo de Urgencias Medicas Cruz Blanca SRL
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Instituto de Cardiologia de Corrientes Juana Francisca Cabral
Corrientes, W3400AMZ, Argentina
Instituto Medico DAMIC - Fundacion Rusculleda
Córdoba, X5003DCE, Argentina
Cordis Sa
Salta, A4400ANW, Argentina
Clinica El Castano
San Juan, J5400ARW, Argentina
Instituto Cardiovascular San Luis
San Luis, D5702JRS, Argentina
Centro de Investigaciones Clinicas del Litoral
Santa Fe, S3000FWO, Argentina
Canberra Hospital
Garran, Australian Capital Territory, 2605, Australia
Royal Prince Alfred Hospital
Camperdown, New South Wales, 2050, Australia
Liverpool Hospital
Liverpool, New South Wales, 2170, Australia
Australian Clinical Research Network
Maroubra, New South Wales, 2035, Australia
Heartcare Partners
Auchenflower, Queensland, 4066, Australia
Bundaberg Cardiology
Bundaberg, Queensland, 4670, Australia
Holdsworth House Medical Brisbane
Fortitude Valley, Queensland, 4006, Australia
Core Research Group Pty Ltd
Milton, Queensland, 4064, Australia
Heart and Vascular Research
Adelaide, South Australia, 5000, Australia
Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
SA Heart
Ashford, South Australia, 5035, Australia
Adelaide Cardiology Practice - Leabrook Clinic
Leabrook, South Australia, 5068, Australia
Royal Hobart Hospital
Hobart, Tasmania, 7000, Australia
HeartCare Victoria - Berwick
Berwick, Victoria, 3806, Australia
Monash Medical Centre
Clayton, Victoria, 3168, Australia
The Cardiologists Proprietary Limited
Epping, Victoria, 3076, Australia
Barwon Health Geelong Hospital
Geelong, Victoria, 3220, Australia
GenesisCare Ringwood
Ringwood, Victoria, 3134, Australia
Curtin University Centre of Clinical Research and Education
Bentley, Western Australia, 6102, Australia
HeartCare Western Australia - Joondalup
Joondalup, Western Australia, 5068, Australia
Fiona Stanley Hospital
Murdoch, Western Australia, 6150, Australia
Dr Heart Pty Ltd
Woolloongabba, 4102, Australia
Landeskrankenhaus Feldkirch
Feldkirch, 6800, Austria
Medizinische Universitaet Graz
Graz, 8036, Austria
Medizinische Universitaet Innsbruck
Innsbruck, 6020, Austria
Klinikum Klagenfurt am Woerthersee
Klagenfurt, 9020, Austria
Ordensklinikum Linz Barmherzige Schwestern
Linz, 4010, Austria
Klinik Landstrasse
Vienna, 1030, Austria
Zentrum fuer klinische Studien - Dr Hanusch GmbH
Vienna, 1060, Austria
Universitaetsklinikum Allgemeines Krankenhaus Wien
Vienna, 1090, Austria
Klinik Hietzing
Vienna, 1130, Austria
Klinik Ottakring
Vienna, 1160, Austria
Algemeen Stedelijk Ziekenhuis Aalst
Aalst, 9300, Belgium
Onze Lieve Vrouw Ziekenhuis - campus Aalst
Aalst, 9300, Belgium
Ziekenhuis Netwerk Antwerpen Middelheim
Antwerp, 2020, Belgium
Ziekenhuis Netwerk Antwerpen Stuivenberg
Antwerp, 2060, Belgium
Universite Catholique de Louvain Cliniques Universitaires Saint Luc
Brussels, 1200, Belgium
AZ Sint Blasius
Dendermonde, 9200, Belgium
Algemeen Ziekenhuis Sint Lucas
Ghent, 9000, Belgium
Medif sprl
Gozée, 6534, Belgium
Dokter Mortelmans bvba
Ham, 3945, Belgium
Jessa Ziekenhuis - Campus Virga Jesse
Hasselt, 3500, Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
Leuven, 3000, Belgium
Medilink sprl
Linkebeek, 1630, Belgium
Centre Hospitalier Universitair Ambroise Pare
Mons, 7000, Belgium
Maria Ziekenhuis Noord-Limburg
Overpelt, 3900, Belgium
Testumed vzw
Tessenderlo, 3980, Belgium
Centro de Pesquisas em Diabetes e Doencas Endocrino Metabolicas
Fortaleza, Ceará, 60430-350, Brazil
Centro de Pesquisa Clinica do Brasil
Brasília, Federal District, 71625-175, Brazil
Cardresearch Cardiologia Assistencial de Pesquisa
Belo Horizonte, Minas Gerais, 30150-240, Brazil
Fundaçao Hospitalar Sao Francisco de Assis
Belo Horizonte, Minas Gerais, 31110-580, Brazil
Eurolatino Pesquisas Medicas
Uberlândia, Minas Gerais, 38411-186, Brazil
Sociedade Hospitalar Angelina Caron
Campina Grande do Sul, Paraná, 83430-000, Brazil
Quanta Diagnosticos e Terapia
Curitiba, Paraná, 80045-170, Brazil
Puc Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da Pucpr/Epicenter
Curitiba, Paraná, 80230-130, Brazil
Nucleo de Pesquisa Clinica
Curitiba, Paraná, 80730-150, Brazil
Núcleo de Pesquisa em Cirurgia Vascular
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Hospital Nossa Senhora da Conceicao
Porto Alegre, Rio Grande do Sul, 91350-200, Brazil
AngioCor Blumenau
Blumenau, Santa Catarina, 89020-430, Brazil
Centro Especializado em Cardiologia
Campinas, São Paulo, 13010-001, Brazil
Instituto de Pesquisa Clinica de Campinas
Campinas, São Paulo, 13060-080, Brazil
Instituto do Coracao de Marilia
Marília, São Paulo, 17515-000, Brazil
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto
São José do Rio Preto, São Paulo, 15090-000, Brazil
Centro de Pesquisas Clinicas Cpclin
São Paulo, São Paulo, 01228-200, Brazil
IBPClin Instituto Brasil de Pesquisa Clinica
Rio de Janeiro, 20241-180, Brazil
Instituto do Coracao do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo
São Paulo, 05403-000, Brazil
Ambulatory for special outpatient medical aid in Cardiology-Private Practice Dr Elena Dotcheva EOOD
Burgas, 8000, Bulgaria
Multiprofile Hospital for Active Treatment - Haskovo AD
Haskovo, 6300, Bulgaria
Specialty Hospital for Active treatment in Cardiology Sveti Georgi - Pernik OOD
Pernik, 2300, Bulgaria
Medical Center Medconsult OOD
Pleven, 5800, Bulgaria
University Multiprofile Hospital for Active Treatment Dr Georgi Stranski EAD
Pleven, 5800, Bulgaria
University Multiprofile Hospital for Active Treatment Sveti Georgi EAD
Plovdiv, 4001, Bulgaria
Multiprofile Hospital for Active Treatment- Medical Complex- Sveti Ivan Rilski EOOD
Plovdiv, 4003, Bulgaria
Fifth Multiprofile Hospital for Active Treatment - Sofia EAD
Sofia, 1233, Bulgaria
National Multiprofile Transport Hospital Tzar Boris III
Sofia, 1233, Bulgaria
Medical Center for Specialized Medical Care of Cardiovascular Diseases OOD
Sofia, 1309, Bulgaria
Acibadem City Clinic Multiprofile Hospital for Active Treatment Tokuda EAD
Sofia, 1407, Bulgaria
Medical Center Excelsior OOD
Sofia, 1407, Bulgaria
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD
Sofia, 1527, Bulgaria
University Multiprofile Hospital for Active Treatment and Emergency Medicine N I Pirogov EAD
Sofia, 1606, Bulgaria
Diagnostic-Consultative Center Convex EOOD
Sofia, 1680, Bulgaria
Medical Center Kalimat EOOD
Sofia, 1680, Bulgaria
Multiprofile Hospital for Active Treatment Sveta Anna Sofia AD
Sofia, 1750, Bulgaria
Medical Center Orpheus OOD
Stara Zagora, 6000, Bulgaria
Multiprofile Regional Hospital for Active Treatment Dr Stefan Cherkezov AD
Veliko Tarnovo, 5002, Bulgaria
LMC Clinical Research Incorporated
Calgary, Alberta, T2H 2G4, Canada
SMH Cardiology Clinical Trials Incorporated
Surrey, British Columbia, V3V 0C6, Canada
Dr T G Elliott Incorporated - BC Diabetes
Vancouver, British Columbia, V5Y 3W2, Canada
Winnipeg Clinic
Winnipeg, Manitoba, R3C 0N2, Canada
G A Research Associates Limited
Moncton, New Brunswick, E1G 1A7, Canada
Commonwealth Medical Clinic
Mount Pearl, Newfoundland and Labrador, A1N 1W7, Canada
Queen Elizabeth II Health Sciences Centre, Halifax Infirmary
Halifax, Nova Scotia, B3H 3A7, Canada
Heart Health Institute
Ajax, Ontario, L1Z 0B1, Canada
LMC Clinical Research Incorporated
Barrie, Ontario, L4N 7L3, Canada
LMC Clinical Research Incorporated
Brampton, Ontario, L6S 0C6, Canada
Brampton Clinical Trials
Brampton, Ontario, L6Z 4N5, Canada
LMC Clinical Research Incorporated Thornhill
Concord, Ontario, L4K 4M2, Canada
LMC Clinical Research Incorporated
Etobicoke, Ontario, M9R 4E1, Canada
Hamilton Health Sciences Hamilton General Hospital
Hamilton, Ontario, L8L 2X2, Canada
Western Centre for Public Health and Family Medicine - Western University
London, Ontario, N6G 2M1, Canada
My Endo Diabetes and Endocrinology Center
Markham, Ontario, L3P 7P2, Canada
LMC Clinical Research Incorporated
Nepean, Ontario, K2J 0V2, Canada
Partners in Advanced Cardiac Evaluation
Newmarket, Ontario, L3Y 2P6, Canada
SKDS Research Incorporated
Newmarket, Ontario, L3Y 5G8, Canada
Oakville Cardiovascular Research
Oakville, Ontario, L6K 3W7, Canada
Dr James Cha
Oshawa, Ontario, L1J 2K1, Canada
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2, Canada
Bluewater Clinical Research Group Incorporated
Sarnia, Ontario, N7T 4X3, Canada
Heart Health Institute Research Incorporated
Scarborough Village, Ontario, M1B 4Z8, Canada
Corcare Cardiovascular Research
Scarborough Village, Ontario, M1B 5N1, Canada
Womens College Hospital
Toronto, Ontario, M5S 1B2, Canada
North York Diagnostic and Cardiac Centre
Toronto, Ontario, M6B 3H7, Canada
Office of Dr Louis Yao
Weston, Ontario, M9N 1W4, Canada
Ecogene-21
Chicoutimi, Quebec, G7H 7K9, Canada
Manna Research Incorporated
Lévis, Quebec, G6W 0M5, Canada
Clinique Sante Cardio MC
Montreal, Quebec, H1T 3Y7, Canada
Institut de recherches cliniques de Montreal
Montreal, Quebec, H2W 1R7, Canada
McGill University Health Centre - Montreal General Hospital
Montreal, Quebec, H3G 1A4, Canada
Applied Medical Informatics Research Incorporated
Montreal, Quebec, H4A 3T2, Canada
Clinique des Maladies Lipidiques de Quebec Incorporated
Québec, Quebec, G1V 4W2, Canada
Centre intégré de santé et de services sociaux (CISSS) des Laurentides - Unité de recherche clini
Saint-Jérôme, Quebec, J7Z 5T3, Canada
MUDr Igor Karen
Benátky nad Jizerou, 294 71, Czechia
Jessenia as, Nemocnice Beroun
Beroun, 266 01, Czechia
Medicentrum Beroun sro
Beroun, 266 01, Czechia
Medicus Services sro
Brandýs nad Labem, 250 01, Czechia
Amkardia sro
Brno, 602 00, Czechia
CCR Brno sro
Brno, 602 00, Czechia
Centrum pro zdravi sro
Brno, 603 00, Czechia
Kardiologicka ambulance Brno sro
Brno, 612 00, Czechia
Fakultni nemocnice Brno
Brno, 625 00, Czechia
Vojenska nemocnice Brno
Brno, 636 00, Czechia
prof MUDr Lubomir Elbl, CSc, Kardiologicka ambulance
Brno, 638 00, Czechia
Edumed sro, Kardiologicka ambulance
Broumov, 550 01, Czechia
Cevni centrum Ceske Budejovice sro
České Budějovice, 370 11, Czechia
Dika centrum sro
Havirov - Mesto, 736 01, Czechia
Clinical Trial Center Hodonin sro
Hodonín, 695 01, Czechia
Kardio Holesov sro
Holešov, 769 01, Czechia
MUDr Ladislava Harrerova, kardiologicka ordinace
Hradec Králové, 500 02, Czechia
Karlovarska krajska nemocnice
Karlovy Vary, 360 01, Czechia
Oblastni nemocnice Kladno as
Kladno, 272 59, Czechia
Kardio Michal Cepelak sro
Klatovy IV, 339 01, Czechia
Oblastni nemocnice Kolin as
Kolin III, 280 02, Czechia
Krajska nemocnice Liberec as
Liberec, 460 63, Czechia
KardioBusak sro
Louny, 440 01, Czechia
Kardio Pudich s.r.o.
Ludgeřovice, 747 14, Czechia
Vseobecna intermi ambulance sro
Milevsko, 399 01, Czechia
MUDr Zbynek Kosek, kardiologicka ambulance sro
Mladá Boleslav, 293 01, Czechia
Pozdisek sro, Kardiologicka ambulance
Mohelnice, 789 85, Czechia
CCR Ostrava sro
Ostrava, 702 00, Czechia
Mestska nemocnice Ostrava
Ostrava, 728 80, Czechia
Benedor sro - Kardiologicka, cevni a interni ambulance
Ostrava - Poruba, 708 00, Czechia
Kardiologicka a angiologicka ambulance
Ostrava-Dubina, 700 30, Czechia
Center for Clinical Research Pardubice, sro
Pardubice, 530 02, Czechia
Nemocnice Pardubickeho kraje as
Pardubice, 532 03, Czechia
Kardiologie v sadech sro
Pilsen, 310 01, Czechia
Ordinace pro choroby srdce a cev
Prague, 101 00, Czechia
Diabet2 sro
Prague, 110 00, Czechia
Vseobecna fakultni nemocnice v Praze
Prague, 128 08, Czechia
CCR Prague sro
Prague, 130 00, Czechia
Thomayerova nemocnice
Prague, 140 59, Czechia
Milan Kvapil sro
Prague, 149 00, Czechia
Fakultni nemocnice v Motole
Prague, 150 06, Czechia
Interni a kardiologicka ordinace
Prague, 158 00, Czechia
Endokrinologie Cerny Most sro
Prague, 198 00, Czechia
Kardiologie Cor sro
Praha 10 - Zabehlice, 106 00, Czechia
Kardiologicke centrum MUDr Janky Skrobakove sro
Praha 5 - Smichov, 150 00, Czechia
Kardio Vaclavik sro, Interni a kardiologicka ambulance
Přerov, 750 02, Czechia
Vestra Clinics sro
Rychnov nad Kněžnou, 516 01, Czechia
Nemocnice Pardubickeho kraje as, Svitavska nemocnice
Svitavy, 568 25, Czechia
AeskuLab ks, Lipidova poradna
Teplice, 415 01, Czechia
Nemocnice Podlesi as
Třinec, 739 61, Czechia
Clinical Trials Service sro
Uherské Hradiště, 686 01, Czechia
Interni ambulance
Uherské Hradiště, 686 01, Czechia
Lekarsky dum Ormiga
Zlín, 760 01, Czechia
KIGE sro
Znojmo, 669 02, Czechia
Aalborg Hospital
Aalborg, 9000, Denmark
Center for Clinical and Basic Research Aalborg
Aalborg, 9000, Denmark
Aarhus Universitetshospital
Aarhus N, 8200, Denmark
Centre for Clinical and Basic Research Ballerup
Ballerup Municipality, 2750, Denmark
Sydvestjysk Sygehus
Esbjerg, 6700, Denmark
Sanos Clinic
Herlev, 2730, Denmark
Steno Diabetes Center
Herlev, 2730, Denmark
Regionhospitalet Herning
Herning, 7400, Denmark
Hillerod Hospital
Hillerød, 3400, Denmark
Kolding Sygehus
Kolding, 6000, Denmark
Amager Hospital
København S, 2300, Denmark
Rigshospitalet Kobenhavn
København Ø, 2100, Denmark
Regionshospitalet Silkeborg
Silkeborg, 8600, Denmark
Svendborg Sygehus
Svendborg, 5700, Denmark
Center for Clinical and Basic Research Vejle
Vejle, 7100, Denmark
Regionshospitalet Viborg
Viborg, 8800, Denmark
Liina Viitas OU
Pärnu, 80014, Estonia
Center for Clinical and Basic Research Tallinn
Tallinn, 10128, Estonia
Dr Arvo Rosenthal LLC
Tallinn, 13419, Estonia
North Estonia Medical Centre Foundation
Tallinn, 13419, Estonia
Helsinki University Central Hospital
Helsinki, 00029, Finland
GERI-MED Oy
Helsinki, 00100, Finland
Pohjois-Karjalan keskussairaala
Joensuu, 80210, Finland
Terveystalo Jyvaskyla
Jyväskylä, 40100, Finland
Studycor Oy
Jyväskylä, 40620, Finland
Satucon Oy/Kuopion tyoterveys
Kuopio, 70100, Finland
University of Eastern Finland
Kuopio, 70210, Finland
Oulu University Hospital
Oulu, 90029, Finland
Oulu University Hospital
Oulu, 90220, Finland
Tampere University Hospital
Tampere, 33520, Finland
Terveystalo Pulssi
Turku, 20100, Finland
Centre Hospitalier Universitaire Amiens - Hopital Sud
Amiens, 80054, France
Hospices Civils de Lyon Groupement Hospitalier Est, Hopital Louis Pradel
Bron, 69677, France
Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre
Caen, 14033, France
Centre Hospitalier Sud Francilien
Corbeil-Essonnes, 91106, France
Centre Hospitalier Universitaire de Dijon - Hopital Francois Mitterrand
Dijon, 21079, France
Groupement Hospitalier Mutualiste
Grenoble, 38000, France
Centre Hospitalier Universitaire de Grenoble - Hopital Nord Michallon
Grenoble, 38700, France
Centre Hospitalier de Versailles - Hopital Andre Mignot
Le Chesnay, 78150, France
Hopital Louis Pasteur
Le Coudray, 28630, France
Centre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon
Lille, 59037, France
Centre Hospitalier Universitaire de Lyon - Hopital Edouard Herriot
Lyon Cédex 3, 69437, France
Hopital Saint-Joseph
Marseille, 13285, France
Centre Hospitalier Universitaire de Marseille - Hôpital de la Timone
Marseille, 13385, France
Centre Hospitalier Regional Universitaire de Montpellier - Hopital Arnaud de Villeneuve
Montpellier, 34295, France
Centre Hospitalier Universitaire de Nantes - Hopital Guillaume et Rene Laennec
Nantes, 44093, France
Centre Hospitalier Universitaire de Nice - Hopital Pasteur
Nice, 06002, France
Centre Hospitalier Universitaire de Nimes
Nîmes, 30029, France
Hopital Saint Antoine
Paris, 75012, France
Hopital Pitie-Salpetriere
Paris, 75013, France
Hopital Europeen Georges Pompidou
Paris, 75015, France
Hopital Bichat Claude Bernard
Paris, 75018, France
Centre Hospitalier de Pau - Hopital Francois Mitterrand
Pau, 64000, France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
Rennes, 35033, France
Clinique Saint Hilaire
Rouen, 76000, France
Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil
Toulouse, 31059, France
Clinique Pasteur
Toulouse, 31076, France
Polyclinique Vauban
Valenciennes, 59300, France
Universitaets-Herzzentrum Freiburg - Bad Krozingen
Bad Krozingen, 79189, Germany
Kerckhoff-Klinik Forschungs GmbH
Bad Neuheim, 61231, Germany
Klinische Forschung Berlin GbR
Berlin, 10787, Germany
Charite Universitätsmedizin Berlin, Charité Campus Virchow-Klinikum
Berlin, 13353, Germany
Kardiologisch - Angiologische Praxis - Herzzentrum Bremen
Bremen, 28277, Germany
Sankt-Johannes-Hospital
Dortmund, 44137, Germany
Cardiologicum Dresden und Pirna
Dresden, 01277, Germany
Diabetologische Gemeinschaftspraxis Dr Schaper und Dr Faulmann
Dresden, 01279, Germany
Universitaetsklinikum Carl Gustav Carus, Medizinische Klinik und Poliklinik III
Dresden, 01307, Germany
Klinikum und Fachbereich Medizin Johann Wolfgang Goethe-Universität Frankfurt am Main
Frankfurt am Main, 60590, Germany
Clin Phenomics GmbH Co KG
Frankfurt am Main, 60596, Germany
Medizinisches Versorgungszentrum im Altstadt-Carree Fulda
Fulda, 36037, Germany
Cardiologicum Hamburg
Hamburg, 22041, Germany
Universitätsklinikum Heidelberg
Heidelberg, 69120, Germany
Ambulantes Herzzentrum Kassel
Kassel, 34121, Germany
Universitätsklinikum Leipzig
Leipzig, 4103, Germany
Otto von Guericke Universität Magdeburg
Magdeburg, 39120, Germany
Johannes Gutenberg Universitaet Mainz
Mainz, 55131, Germany
Universitätsklinikum Mannheim
Mannheim, 68167, Germany
Praxis Doktor Jens Taggeselle
Markleeberg, 04416, Germany
Deutsches Herzzentrum München des Freistaates Bayern
München, 80636, Germany
Herz Gefaess Zentrum Nymphenburg
München, 80638, Germany
Universitaetsklinikum Muenster
Münster, 48149, Germany
Kardiologische Gemeinschaftspraxis Papenburg
Papenburg, 26871, Germany
Klinikum Ernst von Bergmann gGmbH
Potsdam, 14467, Germany
Universitätsklinikum Regensburg
Regensburg, 93053, Germany
CardioConsil GmbH
Rostock, 18059, Germany
I Medizinische Klinik Gesundheitsverbund Landkreis Konstanz
Singen, 78224, Germany
Universitätsklinikum Ulm
Ulm, 89081, Germany
Nephrologisches Zentrum Villingen-Schwenningen
Villingen-Schwenningen, 78052, Germany
Forschungszentrum Ruhr
Witten, 58455, Germany
General Hospital of Athens Evaggelismos
Athens, 10676, Greece
Athens Naval Hospital
Athens, 11521, Greece
General Hospital of Athens Georgios Gennimatas
Athens, 11527, Greece
General Hospital of Athens Ippokrateio
Athens, 11527, Greece
General Hospital of Athens Laiko
Athens, 11527, Greece
Alexandra Hospital
Athens, 11528, Greece
Konstantopoulio - Agia Olga Hospital of Nea Ionia
Athens, 14233, Greece
Hygeia Hospital
Athens, 15123, Greece
University Hospital of Heraklion
Heraklion, 71110, Greece
University Hospital of Ioannina
Ioannina, 45500, Greece
University Hospital of Larissa
Larissa, 41110, Greece
Ahepa University Hospital
Thessaloniki, 54636, Greece
General Hospital of Thessaloniki Ahepa
Thessaloniki, 54636, Greece
Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 56403, Greece
Interbalkan Medical Center
Thessaloniki, 57001, Greece
Lausmed Kft
Baja, 6500, Hungary
Allami Szivkorhaz Balatonfured
Balatonfüred, 8230, Hungary
Balatonmariafurdo Kozseg Onkormanyzatanak Haziorvosi Rendeloje
Balatonkeresztúr, 8647, Hungary
Med-Edu Bt
Ballószög, 6035, Hungary
Grof Tisza Istvan Korhaz
Berettyóújfalu, 4100, Hungary
Dr Lakatos Ferenc Private Cardiology Practice
Békéscsaba, 5600, Hungary
Betegapolo Irgalmas Rend - Budai Irgalmasrendi Korhaz
Budapest, 1023, Hungary
Clinexpert Kft
Budapest, 1033, Hungary
Obudai Egeszsegugyi Centrum Kft
Budapest, 1036, Hungary
Semmelweis Egyetem Varosmajori Sziv- es Ergyogyaszati Klinika
Budapest, 1085, Hungary
Gottsegen Gyorgy Orszagos Kardiologiai Intezet
Budapest, 1096, Hungary
Bajcsy-Zsilinszky Korhaz es Rendelointezet
Budapest, 1106, Hungary
Semmelweis Egyetem
Budapest, 1122, Hungary
Magyar Honvedseg Egeszsegugyi Kozpont
Budapest, 1134, Hungary
Uzsoki Utcai Korhaz
Budapest, 1145, Hungary
Zugloi Egeszsegugyi Szolgalat
Budapest, 1148, Hungary
Jahn Ferenc Del-pesti Korhaz es Rendelointezet
Budapest, 1204, Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen, 4032, Hungary
Markhot Ferenc Oktatokorhaz es Rendelointezet
Eger, 3300, Hungary
Erzsebet Gondozohaz
Gödöllő, 2100, Hungary
Bugat Pal Korhaz
Gyöngyös, 3200, Hungary
Pharma4 Trial Kft
Gyöngyös, 3200, Hungary
Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz
Gyula, 5700, Hungary
BKS Research Kft
Hatvan, 3000, Hungary
Bacs-Kiskun Megyei Korhaz Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar Oktato Korhaza
Kalocsa, 6300, Hungary
Selye Janos Korhaz
Komárom, 2921, Hungary
Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz
Miskolc, 3526, Hungary
CRU Hungary Kft
Miskolc, 3529, Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont
Pécs, 7624, Hungary
Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet
Sopron, 9400, Hungary
Szegedi Tudomanyegyetem Szent Gyorgyi Albert Klinikai Kozpont Altalanos Orvostudomanyi Kar
Szeged, 6725, Hungary
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont Altalanos Orvostudomanyi Kar
Szeged, 6725, Hungary
Tolna Megyei Balassa Janos Korhaz
Szekszárd, 7100, Hungary
Csongrad Megyei Dr Bugyi Istvan Korhaz
Szentes, 6600, Hungary
Praxispont Belvarosi Maganegeszsegugyi Kozpont
Székesfehérvár, 8000, Hungary
Jasz-Nagykun-Szolnok Megyei Hetenyi Geza Korhaz-Rendelointezet
Szolnok, 5004, Hungary
Belvarosi Egeszseghaz Kft
Zalaegerszeg, 8900, Hungary
Hjartamidstodin
Kopavogur, 201, Iceland
Landspitali
Reykjavik, 101, Iceland
Ospedale Muscatello
Augusta, 96011, Italy
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII
Bergamo, 24127, Italy
Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi
Bologna, 40138, Italy
Azienda Ospedaliero Universitaria Mater Domini
Catanzaro, 88100, Italy
Universita degli Studi Gabriele D Annunzio di Chieti e Pescara
Chieti, 66100, Italy
Fondazione Toscana Gabriele Monasterio Ospedale del Cuore G Pasquinucci
Massa, 54100, Italy
IRCCS Ospedale San Raffaele
Milan, 20132, Italy
Centro Cardiologico Monzino
Milan, 20138, Italy
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Milan, 20162, Italy
Azienda Ospedaliero Universitaria Pisana
Pisa, 56100, Italy
Presidio Ospedaliero Santa Maria delle Grazie
Pozzuoli, 80078, Italy
Policlinico Universitario Campus Biomedico
Roma, 00128, Italy
Azienda Ospedaliera Sant Andrea
Roma, 00189, Italy
IRCCS Policlinico San Donato
San Donato Milanese, 20097, Italy
Azienda Ospedaliera Citta della Salute e della Scienza di Torino
Torino, 10126, Italy
Azienda Ospedaliero Universitaria Integrata di Udine
Udine, 33100, Italy
Daugavpils Regional Hospital
Daugavpils, 5417, Latvia
Dace Teterovska Doctor Practice in Endocrinology
Ogre, 5001, Latvia
Inga Jasinkevica Cardiologist Practice
Ogre, 5001, Latvia
Pauls Stradins Clinical University Hospital
Riga, 1002, Latvia
Outpatient Clinic Veselibas Centrs 4
Riga, 1012, Latvia
Klinikiniai sprendimai, UAB
Alytus, 63200, Lithuania
Klinikiniai sprendimai, UAB
Kaunas, 49387, Lithuania
Saules Seimos Medicinos Centras
Kaunas, 49456, Lithuania
Hospital of Lithuanian University of Health Sciences Kaunas Clinics Public Institution
Kaunas, 50009, Lithuania
Kardiologijos ir reabilitacijos klinika, UAB
Klaipėda, 91131, Lithuania
Siauliai Republican Hospital, Public Institution
Šiauliai, 76231, Lithuania
Vilnius University Hospital Santaros Clinic Public Institution
Vilnius, 08661, Lithuania
Clinstile SA de CV
Cd de Mexico, Mexico City, 06700, Mexico
Unidad Biomedica Avanzada Monterrey
Monterrey, Nuevo León, 64460, Mexico
Centro de Estudios Clinicos de Queretaro
Querétaro City, Querétaro, 76000, Mexico
Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada SC
Culiacán, Sinaloa, 80230, Mexico
Centro de investigacion Cardiometabolica
Aguascalientes, 20230, Mexico
Scientia Investigacion Clinica Sc
Chihuahua City, 31203, Mexico
Noordwest Ziekenhuisgroep
Alkmaar, 1815 JD, Netherlands
Ziekenhuisgroep Twente
Almelo, 7609 PP, Netherlands
Emotional Brain
Almere Stad, 1311 RL, Netherlands
Meander Medisch Centrum
Amersfoort, 3813 TZ, Netherlands
Onze Lieve Vrouwe Gasthuis
Amsterdam, 1061 AE, Netherlands
Onze Lieve Vrouwe Gasthuis
Amsterdam, 1091 AC, Netherlands
Academisch Medisch Centrum
Amsterdam, 1105 AZ, Netherlands
Gelre Ziekenhuis
Apeldoorn, 7334 DZ, Netherlands
Rijnstate Ziekenhuis
Arnhem, 6815 AD, Netherlands
Rode Kruis Ziekenhuis
Beverwijk, 1942 LE, Netherlands
Amphia ziekenhuis
Breda, 4818 CK, Netherlands
Reinier de Graaf Gasthuis
Delft, 2625 AD, Netherlands
Deventer Ziekenhuis
Deventer, 7416 SE, Netherlands
Van Weel Bethesda Ziekenhuis
Dirksland, 3247 BW, Netherlands
Albert Schweitzer Ziekenhuis location Dordwijk
Dordrecht, 3318 AT, Netherlands
Albert Schweitzer Ziekenhuis, Locatie Dordwijk
Dordrecht, 3318 AT, Netherlands
Ziekenhuis Gelderse Vallei
Ede, 6716 RP, Netherlands
Catharina Ziekenhuis
Eindhoven, 5623 EJ, Netherlands
Treant Zorggroep, locatie Scheper ziekenhuis Emmen
Emmen, 7824 AA, Netherlands
Medisch Spectrum Twente
Enschede, 7512 KZ, Netherlands
Admiraal de Ruyter Ziekenhuis
Goes, 4462 RA, Netherlands
Groene Hart Ziekenhuis
Gouda, 2803 HH, Netherlands
Martini Ziekenhuis
Groningen, 9728 NT, Netherlands
Sint Jansdal Ziekenhuis
Harderwijk, 3844 DG, Netherlands
Zuyderland Medisch Centrum
Heerlen, 6419 PC, Netherlands
Elkerliek Ziekenhuis
Helmond, 5707 HA, Netherlands
Tergooi
Hilversum, 1213 XZ, Netherlands
Bethesda Diabetes Research Center
Hoogeveen, 7909 AA, Netherlands
Dijklander Ziekenhuis Hoorn
Hoorn, 1624 NP, Netherlands
Medisch Centrum Leeuwarden
Leeuwarden, 8934 AD, Netherlands
Leids Universitair Medisch Centrum
Leiden, 2333 ZA, Netherlands
Isala Diaconessenhuis
Meppel, 7943 KA, Netherlands
Sint Antonius Ziekenhuis, locatie Nieuwegein
Nieuwegein, 3435 CM, Netherlands
Radboudumc
Nijmegen, 6525 GA, Netherlands
Canisius-Wilhelmina Ziekenhuis
Nijmegen, 6532 SZ, Netherlands
Franciscus Gasthuis
Rotterdam, 3045 PM, Netherlands
Praktijk Soerland
Rotterdam, 3067 GJ, Netherlands
Maasstad Ziekenhuis
Rotterdam, 3079 DZ, Netherlands
Ikazia Ziekenhuis
Rotterdam, 3083 AN, Netherlands
Franciscus Vlietland
Schiedam, 3118 JH, Netherlands
D&A Research and Genetics
Sneek, 8601 ZR, Netherlands
Haga Ziekenhuis
The Hague, 2545 AA, Netherlands
Huisartsenpraktijk Rambharose
The Hague, 2572 GM, Netherlands
Ziekenhuis Rivierenland
Tiel, 4002 WP, Netherlands
Elisabeth-Tweesteden Ziekenhuis
Tilburg, 5042 AD, Netherlands
Ziekenhuis Bernhoven
Uden, 5406 PT, Netherlands
Diakonessenhuis
Utrecht, 3582 KE, Netherlands
Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
VieCuri Medisch Centrum
Venlo, 5912 BL, Netherlands
Zaans Medisch Centrum
Zaandam, 1502 DV, Netherlands
Albert Schweitzer Ziekenhuis
Zwijndrecht, 3331 LZ, Netherlands
Dokters van Nederhoven
Zwijndrecht, 3334 SB, Netherlands
Isala Klinieken
Zwolle, 8025 AB, Netherlands
Szpital Uniwersytecki nr 1 im dr Antoniego Jurasza w Bydgoszczy
Bydgoszcz, 85-094, Poland
American Heart of Poland Sa Malopolskie Centrum Sercowo-Naczyniowe PAKS - Chrzanow
Chrzanów, 32-500, Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, 80-219, Poland
Copernicus Podmiot Leczniczy Sp zoo
Gdansk, 80-462, Poland
NZOZ Srodmiescie Spzoo
Gdynia, 81-394, Poland
Marek Piepiorka Gabinet Kardiologiczno-Internistyczny
Gdynia, 81-472, Poland
Spolka Cywilna Medicina
Giżycko, 11-500, Poland
Samodzielny Publiczny Specjalistyczny Szpital Zachodni im swietego Jana Pawla II
Grodzisk Mazowiecki, 05-825, Poland
Biokinetica SA
Józefów, 05-410, Poland
Centrum Medyczne Pratia Katowice
Katowice, 40-081, Poland
Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego Beata Wozakowska-Kaplon
Kielce, 25-525, Poland
Wojewodzki Szpital Zespolony w Kielcach
Kielce, 25-736, Poland
Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska
Krakow, 30-082, Poland
Zespol Przychodni Specjalistycznych Diab-End-Cor Sp z oo
Krakow, 31-135, Poland
Krakowskie Centrum Medyczne Spzoo
Krakow, 31-501, Poland
CARINTART Sp zoo Krakowskie Centrum Diagnostyczno-Kliniczne
Krakow, 31-514, Poland
Intercard Spzoo Centrum Kardiologii Inwazyjnej Elektroterapii i Angiologii w Krosnie
Krosno, 38-400, Poland
Wojewodzki Specjalistyczny Szpital im dr Wladyslawa Bieganskiego w Lodzi
Lodz, 91-347, Poland
Instytut Centrum Zdrowia Matki Polki
Lodz, 93-338, Poland
Miedziowe Centrum Zdrowia Spolka Akcyjna
Lubin, 59-300, Poland
CenterMed Lublin Spzoo
Lublin, 20-044, Poland
Clinical Best Solutions Sp zoo Spolka komandytowa Gabinet Lekarski
Lublin, 20-078, Poland
Ko-med Centra Kliniczne Lublin II
Lublin, 20-362, Poland
NZOZ Twoja Przychodnia Spzoo
Lublin, 20-857, Poland
Szpital Swietej Anny w Miechowie
Miechów, 32-200, Poland
Podhalanski Szpital Specjalistyczny im Jana Pawla II w Nowym Targu
Nowy Targ, 34-400, Poland
Centrum Medyczne Pulawska spzoo Centrum Medyczne Pulawska NZOZ
Piaseczno, 05-500, Poland
Clinical Research Center Spzoo Medic-R Spolka Komandytowa
Poznan, 60-848, Poland
KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Pulawy
Puławy, 24-100, Poland
NZOZ Specjalistyczna Przychodnia Lekarska Medikard
Płock, 09-402, Poland
NZOZ Przychodnia Specjalistyczna Andrzej Wittek Henryk Rudzki spolka jawna
Ruda Śląska, 41-709, Poland
Clinical Best Solutions Spolka z ograniczona odpowiedzialnoscia Spolka komandytowa
Siedlce, 08-110, Poland
ETG Network Spzoo
Skierniewice, 96-100, Poland
KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Staszow
Staszów, 28-200, Poland
Indywidualna Specjalistyczna Praktyka Lekarska
Szczecin, 70-506, Poland
Tomasz Blicharski Lubelskie Centrum Diagnostyczne
Świdnik, 21-040, Poland
Centrum Szybkiej Diagnostyki Kardiologicznej Kardiomed M Zabowka E Zabowka Spolka cywilna
Tarnów, 33-100, Poland
Medical Trials Institute Spzoo
Torun, 87-100, Poland
Prywatne Centrum Kardiologii
Torun, 87-100, Poland
Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu
Torun, 87-100, Poland
Centrum Medyczne Amed Warszawa Zoliborz
Warsaw, 01-518, Poland
Centrum Medyczne Pratia Warszawa
Warsaw, 01-868, Poland
Clinical Best Solutions Sp zoo Spolka komandytowa
Warsaw, 02-793, Poland
Instytut Psychiatrii i Neurologii
Warsaw, 02-957, Poland
Szpital Grochowski imienia Doktora medycyny Rafala Masztaka Spzoo
Warsaw, 04-073, Poland
Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Wegrowie
Węgrów, 07-100, Poland
Futuremeds spolka z ograniczona odpowiedzialnoscia
Wroclaw, 50-088, Poland
Centrum Kardiologiczne Pro Corde Spzoo Centrum Kardiologicne Pro Corde Wroclaw
Wroclaw, 50-315, Poland
Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska
Wroclaw, 51-162, Poland
Medicor Plus Kardiolodzy Spzoo
Włocławek, 87-800, Poland
KO-MED Centra Kliniczne Spzoo KO-MED Centra Kliniczne Zamosc
Zamość, 22-400, Poland
Samodzielny Publiczny Zakład Opieki Zdrowotnej w Lecznej
Łęczna, 21-010, Poland
Hospital Garcia de Orta, EPE
Almada, 2801-951, Portugal
Centro Hospitalar do Baixo Vouga, EPE - Hospital Infante Dom Pedro
Aveiro, 3814-501, Portugal
Centro Hospitalar de Lisboa Ocidental, EPE - Hospital de Santa Cruz
Carnaxide, 2790-134, Portugal
Centro Hospitalar e Universitario de Coimbra EPE
Coimbra, 3000-075, Portugal
Hospital de Faro, EPE
Faro, 8000-386, Portugal
Hospital da Senhora da Oliveira, Guimaraes, EPE
Guimarães, 4835-044, Portugal
Associacao Protectora dos Diabeticos de Portugal
Lisbon, 1250-189, Portugal
Unidade Local de Saude de Matosinhos - Hospital Pedro Hispano
Matosinhos Municipality, 4464-513, Portugal
Hospital Casa de Saude Sao Mateus
Viseu, 3500-093, Portugal
SC Centrul Medical de Diagnostic si Tratament Ambulator Neomed S.R.L
Brasov, 500283, Romania
Spitalul Clinic Universitar de Urgenta Elias
Bucharest, 011461, Romania
Institutul de Urgenţă pentru Boli Cardiovasculare "Prof. Dr. C. C. Iliescu",
Bucharest, 022328, Romania
Spitalul Universitar de Urgenta Bucuresti
Bucharest, 050098, Romania
Cardiomed SRL
Craiova, 200512, Romania
Consultmed SRL
Iași, 700547, Romania
SC Cardiomed SRL
Iași, 700732, Romania
SC Endodigest SRL
Oradea, 410151, Romania
SC Sal Med SRL
Piteşti, 110438, Romania
Mediab SRL
Târgu Mureş, 540142, Romania
CMI Dr Podoleanu Cristian
Târgu Mureş, 540143, Romania
First City Clinical Hospital na E E Volosevich
Arkhangelsk, 163001, Russia
NSHI Departmental Hospital at the station Barnaul of OJSC Russian Railways
Barnaul, 656038, Russia
Regional State Budget Health care Institution Altay Regional Cardiology Dispensary
Barnaul, 656055, Russia
Regional Budget Healthcare Institution Cardiology Dispensary
Ivanovo, 153012, Russia
BHI of Republic Udmurtiya City clinical hospital 9 of Ministry of healthcare of Republic Udmurtiya
Izhevsk, 426063, Russia
FSBI Heart and Vessels Diseases complex problems Scientific Research Institution
Kemerovo, 650002, Russia
Kirov Regional State Budget Healthcare Institution Kirov City Clinical Hospital 1
Kirov, 610014, Russia
Regional Clinical Hospital 2 of the Ministry of Health Krasnodar region
Krasnodar, 350012, Russia
SBHI Scientific Research Institute Regional Clinical Hospital 1 named after S V Ochapovsky
Krasnodar, 350086, Russia
National Medical Research Center for therapy and preventive medicine
Moscow, 101990, Russia
Moscow SBHI City Clinical Hospital 15 n a O M Filatov of Moscow Healthcare Department
Moscow, 111539, Russia
SBHI of Moscow City clinical hospital 64 of Moscow Healthcare department
Moscow, 117292, Russia
City Clinical Hospital named after Zhadkevich
Moscow, 121374, Russia
FSBI Russian Cardiology Research and Production Complex
Moscow, 121552, Russia
SBHI of Nizhny Novgorod region Nizhny Novgorod regional clinical hospital na N A Semashko
Nizhny Novgorod, 603126, Russia
LLC RC Medical
Novosibirsk, 630005, Russia
SBHI of Novosibirsk Region City clinical hospital 1
Novosibirsk, 630047, Russia
FSBSI Scientific Research Institute of Therapy and preventive medicine
Novosibirsk, 630089, Russia
Budget Healthcare Institution of Omsk region Medical-sanitary unit 9
Omsk, 644018, Russia
Perm Regional Hospital for War Veterans
Perm, 614097, Russia
State Budget Institution of Ryazan Region Regional Clinical Hospital
Ryazan, 390039, Russia
City Polyclinic 27
Saint Petersburg, 190031, Russia
Saint Petersburg State Budget Healthcare Institution City Polyclinic 109
Saint Petersburg, 192283, Russia
Saint Petersburg State Budget Healthcare Institution City Polyclinic 109
Saint Petersburg, 192289, Russia
City polyclinic 25 Nevsky district
Saint Petersburg, 193312, Russia
SBHI Medical and sports dispensary of Krasnogvardeisky district of Saint Petersburg
Saint Petersburg, 195112, Russia
Saint Petersburg SBHI City Hospital 38 named after N A Semashko
Saint Petersburg, 196601, Russia
Almazov National Medical Research Centre
Saint Petersburg, 197341, Russia
Saint Petersburg State Budget Healthcare Institution Pokrovskaya City Hospital
Saint Petersburg, 199106, Russia
LLC Mart
Saint Petersburg, 199178, Russia
LLC Medinef Clinic
Sait-Petersburg, 194044, Russia
Samara Regional Clinical Cardiology Dispensary
Samara, 443070, Russia
Clinical Hospital named after S R Mirotvortsev
Saratov, 410054, Russia
Regional State Budget Helthcare Institution Smolensk Regional Clinical Hospital
Smolensk, 214018, Russia
State Budgetary Health Institution City Hospital 4 of the City of Sochi
Sochi, 354057, Russia
FSBSI Tomsk National Research Medical Center of the Russian Academy of Sciences
Tomsk, 634012, Russia
Tyumen State Medical University
Tyumen, 625023, Russia
State Autonomous Healthcare Institution of the Tyumen region Medical Scientific Practical Center
Tyumen, 625032, Russia
SBHI of Vladimirskaya region City Hospital 4 of Vladimir
Vladimir, 600020, Russia
Family Medicine Clinic
Volgograd, 400001, Russia
Central City Clinical Hospital 1 of the Oktyabrsky District
Yekaterinburg, 620026, Russia
State Budget Medical Institution Sverdlovsk Regional Clinical Hospital N1
Yekaterinburg, 620102, Russia
Alian, sro
Bardejov, 085 01, Slovakia
MediTask, sro
Bratislava, 831 03, Slovakia
Narodny ustav srdcovych a cievnych chorob, as
Bratislava, 833 48, Slovakia
Veria, sro
Bratislava, 851 01, Slovakia
Nemocnica s poliklinikou Brezno, no
Brezno, 977 01, Slovakia
Medical group Kosice sro
Košice, 040 01, Slovakia
Cardio D and R, sro Kosice
Košice, 040 22, Slovakia
Kardio 1 sro
Lučenec, 984 01, Slovakia
Medi M and M sro
Moldava nad Bodvou, 045 01, Slovakia
Oralek, sro
Námestovo, 029 01, Slovakia
Kardiocentrum Nitra sro
Nitra, 949 01, Slovakia
Kardiomed NZ, sro
Nové Zámky, 940 01, Slovakia
Medikard, sro
Prešov, 080 01, Slovakia
Medispol, sro
Prešov, 080 01, Slovakia
Diab sro
Rožňava, 048 01, Slovakia
Mediluk sro
Snina, 069 01, Slovakia
Interna SK, sro
Svidník, 089 01, Slovakia
Areteus sro
Trebišov, 075 01, Slovakia
CardiOr, sro
Trenčín, 911 01, Slovakia
Inje University Busan Paik Hospital
Busan, 47392, South Korea
Dong-A University Hospital
Busan, 49201, South Korea
Chungbuk National University Hospital
Cheongju-si, Chungcheongbuk-do, 28644, South Korea
Yeungnam University Medical Center
Daegu, 42415, South Korea
Keimyung University, Dongsan Hospital
Daegu, 42601, South Korea
Chonnam National University Hospital
Gwangju, 501-757, South Korea
Gachon University Gil Medical Center
Incheon, 21565, South Korea
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
Kyung Hee University Hospital
Seoul, 02447, South Korea
Korea University Anam Hospital
Seoul, 02841, South Korea
Seoul National University Hospital
Seoul, 03080, South Korea
Kangbuk Samsung Hospital
Seoul, 03181, South Korea
Severance Hospital, Yonsei University Health System
Seoul, 03722, South Korea
Asan Medical Center
Seoul, 05505, South Korea
Samsung Medical Center
Seoul, 06351, South Korea
The Catholic University of Korea Seoul St Marys Hospital
Seoul, 06591, South Korea
Gangnam Severance Hospital
Seoul, 135-700, South Korea
Ajou University Hospital
Suwon-si, Gyeonggi-do, 16499, South Korea
Yonsei University Wonju Severance Christian Hospital
Wonju-si, Gangwon-do, 26426, South Korea
Hospital Virgen del Mar
Almería, Andalusia, 04120, Spain
Hospital Universitario Reina Sofia
Córdoba, Andalusia, 14004, Spain
Hospital Universitario Virgen de las Nieves
Granada, Andalusia, 18012, Spain
Hospital Clinico Universitario Virgen de la Victoria
Málaga, Andalusia, 29010, Spain
Hospital Universitario Virgen Macarena
Seville, Andalusia, 41009, Spain
Hospital Universitario Miguel Servet
Zaragoza, Aragon, 50009, Spain
Hospital Universitario de Gran Canaria Doctor Negrin
Las Palmas de Gran Canarias, Canary Islands, 35010, Spain
Hospital Clinico Universitario de Valladolid
Valladolid, Castille and León, 47005, Spain
Hospital Universitari Germans Trias i Pujol
Badalona, Catalonia, 08916, Spain
Equip Atencio Primaria Sardenya
Barcelona, Catalonia, 08025, Spain
Hospital Clinic i Provincial de Barcelona
Barcelona, Catalonia, 08036, Spain
Hospital Universitari Sant Joan de Reus
Reus, Catalonia, 43204, Spain
Complexo Hospitalario Universitario A Coruña
A Coruña, Galicia, 15006, Spain
Hospital Clinico Universitario de Santiago
Santiago de Compostela, Galicia, 15706, Spain
Hospital Alvaro Cunqueiro
Vigo, Galicia, 36312, Spain
Hospital Universitario Virgen de la Arrixaca
El Palmar, Murcia, 30120, Spain
Complejo Hospitalario de Navarra
Pamplona, Navarre, 31008, Spain
Hospital Universitari i Politecnic La Fe
Valencia, Valencia, 26026, Spain
Hospital Clinico Universitario de Valencia
Valencia, Valencia, 46010, Spain
Hospital Universitario de La Princesa
Madrid, 28006, Spain
Fundacion Jimenez Diaz
Madrid, 28040, Spain
Hospital Clinico San Carlos
Madrid, 28040, Spain
Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
Hospital Universitario La Paz
Madrid, 28046, Spain
Hospital Universitario Infanta Sofia
Madrid, 28702, Spain
Sodra Alvsborgs sjukhus
Borås, 501 82, Sweden
Falu Lasarett
Falun, 791 82, Sweden
Carlanderska
Gothenburg, 405 45, Sweden
Sahlgrenska Universitetssjukhus
Gothenburg, 413 45, Sweden
Obackakliniken i Harnosand
Härnösand, 871 31, Sweden
PharmaSite Helsingborg
Helsingborg, 252 20, Sweden
Lanssjukhuset Ryhov
Jönköping, 551 85, Sweden
Centralsjukhuset Karlstad
Karlstad, 651 85, Sweden
Skaraborgs sjukhus Lidkoping
Lidköping, 531 85, Sweden
Clemenstorgets Hjartmottagning
Lund, 222 21, Sweden
PharmaSite Malmo
Malmo, 211 52, Sweden
Ostersunds sjukhus
Östersund, 831 83, Sweden
Akardo MedSite
Stockholm, 117 27, Sweden
Norrlands Universitetssjukhus
Umeå, 901 85, Sweden
Hallands sjukhus Varberg
Varberg, 432 81, Sweden
Hualien Tzu Chi Hospital
Hualien City, Hualien, 97002, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 80756, Taiwan
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 83301, Taiwan
Mackay Memorial Hospital Tamsui Branch
New Taipei City, 25160, Taiwan
Chung Shan Medical University Hospital
Taichung, 40201, Taiwan
Taichung Veterans General Hospital
Taichung, 40705, Taiwan
National Cheng Kung University Hospital
Tainan, 70403, Taiwan
National Taiwan University Hospital
Taipei, 10002, Taiwan
Taipei Veterans General Hospital
Taipei, 11217, Taiwan
Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation
Taoyuan District, 33305, Taiwan
Ivano-Frankivsk Regional Clinical Cardiology Center of Ivano-Frankivsk Regional Council
Ivano-Frankivsk, 76018, Ukraine
Communal Healthcare Institution Kharkiv City Clinical Hospital No27
Kharkiv, 61002, Ukraine
Medical and Sanitary Unit of Open Joint Stock Company Kharkiv Tractor Plant
Kharkiv, 61106, Ukraine
Communal Noncommercial enterprise "City Hospital #8" of Kharkiv City Council
Kharkiv, 61176, Ukraine
Oleksandrivska Clinical Hospital of Kyiv
Kyiv, 01023, Ukraine
Kyiv City Clinical Hospital 1
Kyiv, 02091, Ukraine
Communal Noncommercial Institution Consultative and Diagnostic Center of Desnianskyi District of Kyi
Kyiv, 02232, Ukraine
Kyiv City Clinical Emergency Medical Care Hospital
Kyiv, 02660, Ukraine
National Scientific Center "M.D. Strazhesko Institute of Cardiology"
Kyiv, 03151, Ukraine
State Institution National Scientific Center Acad MD Strazhesko Institute of cardiology of NAMS Ukr
Kyiv, 03680, Ukraine
State Institution National Scientific Center Acad Strazhesko Institute of Cardiology
Kyiv, 03680, Ukraine
Medical Centre CONSILIUM Medical
Kyiv, 04050, Ukraine
Zakarpattia Oblast Clinical Center of Cardiology and Cardio Surgery
Uzhhorod, 88014, Ukraine
Private Small Enterprise, Medical Center Pulse
Vinnytsia, 21001, Ukraine
Vinnytsia M I Pyrogov Regional Clinical Hospital Vinnytsia M I Pyrogov National Medical University
Vinnytsia, 21018, Ukraine
Communal Non-commercial enterprise "City Hospital #6 "of Zaporizhzhia City Council
Zaporizhzhia, 69035, Ukraine
Aberdeen Royal Infirmary
Aberdeen, AB25 2ZN, United Kingdom
Barnsley Hospital
Barnsley, S75 2EP, United Kingdom
Royal United Hospital
Bath, BA1 3NG, United Kingdom
Royal Victoria Hospital
Belfast, BT12 6BA, United Kingdom
Ulster Hospital
Belfast, BT16 1RH, United Kingdom
Ormeau Health Centre
Belfast, BT7 2EB, United Kingdom
Bollington Medical Centre
Bollington, SK10 5JH, United Kingdom
Royal Bournemouth Hospital
Bournemouth, BH7 7DW, United Kingdom
West Walk Surgery
Bristol, BS37 4AX, United Kingdom
University Hospitals of Derby and Burton NHS Foundation Trust
Burton-on-Trent, DE13 0RB, United Kingdom
Ashgate Medical Practice
Chesterfield, S40 4AA, United Kingdom
Cleveleys Group Practice
Cleveleys, FY5 3LF, United Kingdom
Lakeside Healthcare
Corby, NN17 2UR, United Kingdom
Medinova Northamptonshire Dedicated Research Site
Corby, NN18 9EZ, United Kingdom
MeDiNova Warwickshire Quality Research Site
Coventry, CV3 4FJ, United Kingdom
Pound Hill Medical Group
Crawley, RH10 7DX, United Kingdom
Ninewells Hospital
Dundee, DD1 9SY, United Kingdom
Glasgow Royal Infirmary
Glasgow, G31 2ER, United Kingdom
Hull Royal Infirmary
Hull, HU3 2RW, United Kingdom
Highlands Clinical Research Facility, Raigmore Hospital
Inverness, IV2 3JH, United Kingdom
Royal Liverpool University Hospital
Liverpool, L7 8XP, United Kingdom
Barts Health NHS Trust
London, EC1M 6BQ, United Kingdom
Royal Free London NHS Foundation Trust
London, NW3 2QG, United Kingdom
Guys Hospital
London, SE1 9RT, United Kingdom
Wythenshawe Hospital
Manchester, M23 9LT, United Kingdom
Medinova North London Dedicated Research Centre
Northwood, HA6 2RN, United Kingdom
Nottingham City Hospital
Nottingham, NG5 1PB, United Kingdom
George Eliot Hospital
Nuneaton, CV10 7DJ, United Kingdom
Medinova South London Dedicated Research Centre
Orpington, BR5 3QG, United Kingdom
Mounts Bay Medical Hub
Penzance, TR19 7HX, United Kingdom
The Health Centre Yaxley
Peterborough, PE7 1AT, United Kingdom
The Adam Practice
Poole, BH16 5PW, United Kingdom
Medinova East London Dedicated Research Centre
Romford, RM1 3PJ, United Kingdom
Sherbourne Medical Centre
Royal Leamington Spa, CV32 4RA, United Kingdom
Eaton Socon Health Centre
Saint Neots, PE19 8BB, United Kingdom
Ashfield Primary Care Centre
Sandbach, CW11 1EQ, United Kingdom
Scunthorpe General Hospital
Scunthorpe, DN15 7BH, United Kingdom
Medinova Limited
Shipley, BD18 3SA, United Kingdom
Lakeside Healthcare Stamford
Stamford, PE9 2DH, United Kingdom
Lister Hospital
Stevenage, SG1 4AB, United Kingdom
Singleton Hospital
Swansea, SA2 8PP, United Kingdom
The Breckland Alliance
Thetford, IP24 1JD, United Kingdom
Torbay Hospital
Torquay, TQ2 7AA, United Kingdom
Pinderfields Hospital
Wakefield, WF1 4DG, United Kingdom
Sheepcot Medical Practice
Watford, WD25 7NL, United Kingdom
Sandwell General Hospital
West Bromwich, B71 4HJ, United Kingdom
Whitby Group Practice
Whitby, YO21 1SD, United Kingdom
MeDiNova West London Quality Research Site
Wokingham, RG40 1XS, United Kingdom
Worcestershire Royal Hospital
Worcester, WR5 1DD, United Kingdom
Yeovil District Hospital
Yeovil, BA21 4AT, United Kingdom
Related Publications (2)
Bohula EA, Marston NA, Ruzza A, Murphy SA, De Ferrari GM, Diaz R, Leiter LA, Elliott-Davey M, Wang H, Bhatia AK, Giugliano RP, Sabatine MS. Rationale and design of the effect of evolocumab in patients at high cardiovascular risk without prior myocardial infarction or stroke (VESALIUS-CV) trial. Am Heart J. 2024 Mar;269:179-190. doi: 10.1016/j.ahj.2023.12.004. Epub 2023 Dec 29.
PMID: 38160917BACKGROUNDBohula EA, Marston NA, Bhatia AK, De Ferrari GM, Leiter LA, Nicolau JC, Park JG, Kuder JF, Murphy SA, Walsh E, Wang H, Blaha V, Budaj A, Cornel JH, Goudev A, Kiss RG, Lorenzatti AJ, Parkhomenko A, Cyrille M, Paiva da Silva Lima G, Ohman EM, Giugliano RP, Sabatine MS; VESALIUS-CV Investigators. Evolocumab in Patients without a Previous Myocardial Infarction or Stroke. N Engl J Med. 2026 Jan 8;394(2):117-127. doi: 10.1056/NEJMoa2514428. Epub 2025 Nov 8.
PMID: 41211925DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
MD
Amgen
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 11, 2019
First Posted
March 13, 2019
Study Start
June 11, 2019
Primary Completion
July 25, 2025
Study Completion
July 25, 2025
Last Updated
November 10, 2025
Record last verified: 2025-11
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF, CSR
- Time Frame
- Data sharing requests relating to this study will be considered beginning 18 months after the study has ended and either 1) The product and indication have been granted marketing authorization in both the US and Europe or 2) clinical development for the product and/or indication discontinues and the data will not be submitted to regulatory authorities. There is no end date for eligibility to submit a data sharing request for this study.
- Access Criteria
- Qualified researchers may submit a request containing the research objectives, the Amgen product(s) and Amgen study/studies in scope, endpoints/outcomes of interest, statistical analysis plan, data requirements, publication plan, and qualifications of the researcher(s). In general, Amgen does not grant external requests for individual patient data for the purpose of re-evaluating safety and efficacy issues already addressed in the product labelling. Requests are reviewed by a committee of internal advisors. If not approved, a Data Sharing Independent Review Panel will arbitrate and make the final decision. Upon approval, information necessary to address the research question will be provided under the terms of a data sharing agreement. This may include anonymized individual patient data and/or available supporting documents, containing fragments of analysis code where provided in analysis specifications. Further details are available at the link below.
De-identified individual patient data for variables necessary to address the specific research question in an approved data sharing request.