Success Metrics

Clinical Success Rate
87.0%

Based on 60 completed trials

Completion Rate
87%(60/69)
Active Trials
7(7%)
Results Posted
90%(54 trials)
Terminated
9(9%)

Phase Distribution

Ph phase_4
24
24%
Ph early_phase_1
3
3%
Ph phase_1
5
5%
Ph not_applicable
2
2%
Ph phase_2
20
20%
Ph phase_3
34
35%

Phase Distribution

8

Early Stage

20

Mid Stage

58

Late Stage

Phase Distribution88 total trials
Early Phase 1First-in-human
3(3.4%)
Phase 1Safety & dosage
5(5.7%)
Phase 2Efficacy & side effects
20(22.7%)
Phase 3Large-scale testing
34(38.6%)
Phase 4Post-market surveillance
24(27.3%)
N/ANon-phased studies
2(2.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

60 of 72 finished

Non-Completion Rate

16.7%

12 ended early

Currently Active

7

trials recruiting

Total Trials

98

all time

Status Distribution
Active(8)
Completed(60)
Terminated(12)
Other(18)

Detailed Status

Completed60
unknown18
Terminated9
Recruiting5
Withdrawn3
Active, not recruiting2

Development Timeline

Analytics

Development Status

Total Trials
98
Active
7
Success Rate
87.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (3.4%)
Phase 15 (5.7%)
Phase 220 (22.7%)
Phase 334 (38.6%)
Phase 424 (27.3%)
N/A2 (2.3%)

Trials by Status

unknown1818%
completed6061%
not_yet_recruiting11%
recruiting55%
terminated99%
active_not_recruiting22%
withdrawn33%

Recent Activity

Clinical Trials (98)

Showing 20 of 98 trialsScroll for more
NCT03872401Phase 3

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Completed
NCT07612774Phase 4

CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS

Recruiting
NCT03337698Phase 1

A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)

Terminated
NCT05144529Phase 2

A Randomized Pilot Study of Evolocumab Plus Nivolumab/Ipilimumab in Treatment-Naïve Patients With Metastatic NSCLC

Terminated
NCT03515304Phase 2

Evolocumab in Acute Coronary Syndrome

Completed
NCT03829046Phase 4

The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease

Completed
NCT06284564Phase 2

A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC)

Active Not Recruiting
NCT06081153Early Phase 1

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

Not Yet Recruiting
NCT04608474Phase 4

Lipid Management in Renal Transplant Recipients Using Evolocumab.

Completed
NCT06700720Phase 2

YN001-004 in Patients With Coronary Atherosclerosis in Australia

Recruiting
NCT06740552

Evolocumab in Patients With Multivessel Coronary Disease After Acute Myocardial Infarction: A Target Trial Emulation

Completed
NCT05152888Phase 4

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk

Recruiting
NCT04082442Phase 2

Evolocumab in Patients With Acute MI

Completed
NCT05284747Phase 4

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

Active Not Recruiting
NCT03900026Phase 4

Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery

Completed
NCT06858332

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Recruiting
NCT04303377Phase 2

Early Treatment With Evolocumab in Patients With ST-elevation Myocardial Infarction

Withdrawn
NCT04073134Phase 4

The CHORAL Flow Study

Terminated
NCT03689946Phase 3

Effect of Evolocumab on Coronary Atherosclerosis

Completed
NCT04937413Early Phase 1

The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation

Completed

Drug Details

Intervention Type
DRUG
Total Trials
98