Epileptic Seizures in Intensive Care Units
1 other identifier
observational
200
1 country
1
Brief Summary
This retrospective observational cohort study is to assess and analyze clinical, electroencephalographic, laboratory, comorbidity, and treatment characteristics of Intensive care unit (ICU)-patients with epileptic seizures and to subsequently compare their characteristics with ICU-patients with status epilepticus (SE).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 26, 2019
CompletedFirst Posted
Study publicly available on registry
March 4, 2019
CompletedStudy Start
First participant enrolled
December 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2022
CompletedJune 2, 2022
June 1, 2022
2.4 years
February 26, 2019
June 1, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Frequency of epileptic seizures
Frequency of all epileptic seizures in the ICU
between 01.01.2005 and 19.12.2018
Secondary Outcomes (4)
Number of epileptic seizures captured by EEG
between 01.01.2005 and 19.12.2018
Number of epileptic seizures diagnosed on the basis of clinical symptoms alone
between 01.01.2005 and 19.12.2018
Length of epileptic seizure (time)
between 01.01.2005 and 19.12.2018
Semiological feature of epileptic seizure (i.e. seizure types)
between 01.01.2005 and 19.12.2018
Interventions
Patient data will be collected using the in-house digital patient record systems and the local digital electroencephalogram (EEG)-database
Eligibility Criteria
All adult patients (i.e., ≥18 years of age) admitted to the ICUs at the University Hospital Basel that suffered from one or more epileptic seizures (detected clinically and/or by EEG) during their ICU-stay
You may qualify if:
- admitted to the ICU at the University Hospital Basel
- suffered from one or more epileptic seizures (detected clinically and/or by EEG) during their ICU-stay
You may not qualify if:
- patients with epileptic seizures transforming into Status epilepticus (SE)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Clinic for Intensive Care Medicine, University Hospital Basel
Basel, 4031, Switzerland
Related Publications (1)
Wagner AS, Semmlack S, Frei A, Ruegg S, Marsch S, Sutter R. Seizures and risks for recurrence in critically ill patients: an observational cohort study. J Neurol. 2022 Aug;269(8):4185-4194. doi: 10.1007/s00415-022-11038-6. Epub 2022 Mar 2.
PMID: 35235003DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Raoul Sutter, PD Dr. med
Clinic for Intensive Care Medicine, University Hospital Basel
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 26, 2019
First Posted
March 4, 2019
Study Start
December 1, 2019
Primary Completion
April 30, 2022
Study Completion
April 30, 2022
Last Updated
June 2, 2022
Record last verified: 2022-06