Investigation of Patients Presenting With Acute Functional Neurological Symptoms

NCT07538414 | Recruiting

• 1 other identifier: 2026-00643
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases

Conditions

Functional Neurological Disorder

Outcome Measures

Primary Outcomes (1)

• Frequency of FND

  The primary endpoint is the proportion of patients presenting with acute neurological symptoms who receive a diagnosis or likely differential diagnosis of Functional Neurological Disorder (FND) during their index hospital admission.

  At hospital discharge (index admission), up to 30 days from presentation

Secondary Outcomes (8)

• Secondary Outcomes

  At hospital discharge (index admission), up to 30 days from presentation

• Secondary Outcomes

  At hospital discharge (index admission), up to 30 days from presentation

• Secondary Outcomes

  At hospital discharge (index admission), up to 30 days from presentation

• Secondary Outcomes

  At hospital discharge (index admission), up to 30 days from presentation

• Secondary Outcomes

  At hospital discharge (index admission), up to 30 days from presentation

Interventions

collection of patient data OTHER

collection of patient data

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients presenting with acute symptoms

You may qualify if:

• Patients older than 16 years old presenting as an emergency case to the University Hospital Basel between 1 January 2012 and 31 March 2026
• with acute neurological symptoms requiring immediate neurological work-up (e.g, acute motor or sensory disturbance, acute speech disorder, acute vestibular disorder, acute cognitive disorder, acute consciousness disorder, acute seizure disorder)
• and a documented diagnostic evaluation during hospitalization.

You may not qualify if:

• Documented refusal for further use of health related data for research purposes
• Insufficient documentation to determine diagnosis or clinical course
• Incomplete or inconsistent datasets compromising valid endpoint determination
• Younger than 16 years

Sponsors & Collaborators

• University Hospital, Basel, Switzerland: lead

Study Sites (1)

University Hospital Basel

Basel, 4031, Switzerland

RECRUITING

MeSH Terms

Conditions

Conversion Disorder

Condition Hierarchy (Ancestors)

Somatoform Disorders; Mental Disorders

Central Study Contacts

Urs Fisch, MD PhD

CONTACT

+41 61 265 2525; urs.fisch@usb.ch

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: March 30, 2026
• First Posted: April 20, 2026
• Study Start: March 30, 2026
• Primary Completion (Estimated): December 1, 2050
• Study Completion (Estimated): December 1, 2050
• Last Updated: April 20, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)