A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI
1 other identifier
observational
50
0 countries
N/A
Brief Summary
- 1.By following up the prognosis of surgical patients, the application value of Cortex ID quantitative analysis in the localization of epilepsy foci was studied.
- 2.By studying the correlation between autonomic nerve function and epilepsy neural network in epilepsy patients, and analyzing the differences between different epilepsy patients, it can provide more information for judging the prognosis of epilepsy patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Oct 2022
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 26, 2022
CompletedStudy Start
First participant enrolled
October 1, 2022
CompletedFirst Posted
Study publicly available on registry
October 5, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2024
CompletedOctober 5, 2022
October 1, 2022
1.2 years
September 26, 2022
October 4, 2022
Conditions
Outcome Measures
Primary Outcomes (2)
Seizure frequency
2022-2024
Seizure duration
2022-2024
Study Arms (2)
drug-resistant epilepsy
No intervention
Medication is effective
No intervention
Interventions
Eligibility Criteria
Observational study of epilepsy patients treated at the Epilepsy Center of Xijing Hospital
You may qualify if:
- Meet the diagnostic criteria for epilepsy,
- No contraindications for fMRI examination.
- The patient had no other heart and lung diseases except epilepsy.
- Patients and their families were aware of this study and signed informed consent.
You may not qualify if:
- Patients with severe infection, cerebrovascular disease, malignant tumor and other systemic diseases that can affect the nervous system, and those with serious dysfunction of the heart, liver, kidney and other organs.
- Non-epileptic seizures such as syncope and hysteria.
- Pregnant or lactating women. Incomplete clinical data
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Li Shuangshuanglead
Related Publications (1)
Kassinopoulos M, Harper RM, Guye M, Lemieux L, Diehl B. Altered Relationship Between Heart Rate Variability and fMRI-Based Functional Connectivity in People With Epilepsy. Front Neurol. 2021 Jun 10;12:671890. doi: 10.3389/fneur.2021.671890. eCollection 2021.
PMID: 34177777BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
September 26, 2022
First Posted
October 5, 2022
Study Start
October 1, 2022
Primary Completion
December 1, 2023
Study Completion
July 1, 2024
Last Updated
October 5, 2022
Record last verified: 2022-10