The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia
1 other identifier
interventional
8
1 country
1
Brief Summary
The purpose of this study is to investigate the effect of interrupting prolong sedentary behavior with interval exercise on postprandial metabolism following a high fat glucose tolerance test.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2018
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 20, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 8, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
July 8, 2018
CompletedFirst Submitted
Initial submission to the registry
February 25, 2019
CompletedFirst Posted
Study publicly available on registry
February 27, 2019
CompletedFebruary 27, 2019
February 1, 2019
5 months
February 25, 2019
February 25, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Plasma Triglycerides
Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test
6-hours
Secondary Outcomes (2)
Plasma Insulin
6-hours
Plasma Glucose
6-hours
Study Arms (2)
Prolonged sitting without exercise
EXPERIMENTALSubjects will be asked to undergo prolonged sitting (\~14 hours) of 1 day and will not be asked to perform interval exercise.
Prolonged sitting with interval exercise
EXPERIMENTALSubjects will be asked to undergo prolonged sitting (\~14 hours) of 1 day and will be asked to perform interval exercise every hour on the hour.
Interventions
Subjects will have a 2-day control period during which step count and diet will be controlled for and recreated for the other trial. Following this 2-day period, they will undergo the prolonged sitting trial. Day 4 will consist of the lipid tolerance test to determine the ability of the body to clear triglycerides.
Subjects will have a 2-day control period during which step count and diet will be controlled for and recreated for the other trial. Following this 2-day period, they will undergo a prolonged sit which with will be broken up every hour on the hour by a small bout of interval exercise. Day 4 will consist of the lipid tolerance test to determine the ability of the body to clear triglycerides.
Eligibility Criteria
You may not qualify if:
- cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
- respiratory problems
- musculoskeletal problems that prevent prolonged sitting or exercise
- susceptibility to fainting
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Texas at Austin Human Performance Laboratory
Austin, Texas, 78712, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Edward F Coyle, Ph.D.
University of Texas at Austin
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
February 25, 2019
First Posted
February 27, 2019
Study Start
February 20, 2018
Primary Completion
July 8, 2018
Study Completion
July 8, 2018
Last Updated
February 27, 2019
Record last verified: 2019-02
Data Sharing
- IPD Sharing
- Will not share