Shenzhen Birth Cohort Study
1 other identifier
observational
10,000
1 country
1
Brief Summary
The Shenzhen Birth Cohort Study was set up to investigate the effect of early life environmental exposures on short- and long-term health consequences in Shenzhen, China.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 6, 2018
CompletedFirst Submitted
Initial submission to the registry
January 30, 2019
CompletedFirst Posted
Study publicly available on registry
February 5, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 5, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2032
ExpectedFebruary 5, 2019
February 1, 2019
7 years
January 30, 2019
February 1, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Fetal outcomes.
Including intrauterine growth retardation, abortion, stillbirth, live birth, preterm. birth, low birth weight, macrosomia and birth defects.
At delivery.
Secondary Outcomes (5)
Maternal weight changes (kg).
At pre-pregnancy period, 20 weeks of gestation, 28 weeks of gestation, the time before labor and 30 days after delivery.
Number of participant with gestational complications.
At delivery.
Number of participant with postnatal depression.
At 30 days after delivery, 3 months, 6 months after delivery.
Physical development.
at age of 1 month, 3 months, 6months, 1 year, 3 years and 6 years.
Neurodevelopment.
at age of 1 month, 3 months, 6months, 1 year, 3 years and 5 years.
Study Arms (1)
No treatment
This cohort study have any no treatment.
Interventions
Eligibility Criteria
Pregnant women attending their first routine antenatal examinations and their partners and offspring.
You may qualify if:
- \. Pregnant women plan to delivery and participate in child care in our hospital; 2. Pregnant women plan to reside in Shenzhen for at least 7 years; 3. Pregnant women who show interest in the study and agree to provide informed consent; 4. Gestational weeks are less than 20 weeks.Those who will agree that their neonatal will be included in the study and be followed up regularly in our child health clinic until an age of 7 years.
You may not qualify if:
- Pregnant women who have been pregnant for more than 20 weeks; refuse to participate; unable to guarantee delivery in our hospital or can't participate in child care in our hospital; mentally incapacitated and need guardians; or be unwilling to sign informed consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
RuiGao
Shenzhen, Guangdong, 510000, China
Biospecimen
During pregnancy: maternal blood, urine, hair and toenails. At delivery: umbilical cord blood, placenta , umbilical cord, meconium, mother's saliva and milk. During infancy: dry blood spot, stool and blood. During childhood: Mother's saliva, milk, baby's saliva and feces.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate professor
Study Record Dates
First Submitted
January 30, 2019
First Posted
February 5, 2019
Study Start
March 6, 2018
Primary Completion
March 5, 2025
Study Completion (Estimated)
December 31, 2032
Last Updated
February 5, 2019
Record last verified: 2019-02