The Jiaxing Birth Cohort in China
JBC
1 other identifier
observational
500,000
1 country
1
Brief Summary
The Jiaxing Birth Cohort (JBC) is the largest prospective cohort study to explore prenatal risk factors, early life feeding practice and growth pattern/ adiposity in Chinese children.Between 1999 and 2013, 338 413 mother-child pairs were recruited in Jiaxing area in south-east China.Children of the recruited women were followed up at 1-2, 3, 6, 9 and 12 months of age, and subsequently followed up every 6 months to 36 months of age (toddler stage), and every year to 6-7 years of age before they went to school (pre-school stage). Follow-up rate was 70.8% at the toddler stage and 68.9% at the pre-school stage up to June 2013.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 1999
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 1999
CompletedFirst Submitted
Initial submission to the registry
June 18, 2017
CompletedFirst Posted
Study publicly available on registry
July 14, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2029
ExpectedJanuary 23, 2018
January 1, 2018
20 years
June 18, 2017
January 18, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
overweight and obesity
BMI-z-score was calculated from height and weight. BMI-z-score\>1 was defined as overweight/obesity
Up to 6-7 years old for these children
Study Arms (1)
Mother-child birth cohort
Interventions
Eligibility Criteria
Between 1999 and 2013, 363 416 pregnancies were followed from initial registration to the end of the pregnancy, with 25 003 children born to the above women having no further information (registration) after the birth. Therefore, a total of 338 413 live mother-child pairs registered at local clinics, and were enrolled in the Jiaxing Birth Cohort. Among the 338 413 children, there were 332 532 singletons, 2883 pairs of twins (n = 5766), 37 pairs of triplets (n= 111), and 1 pair of quadruplets (n = 4).
You may qualify if:
- Pregnant women came to clinic visit at one of the local hospitals during pregnancy at Jiaxing area
- Pregnant women were followed up during pregnancy and their children were born alive at local hospital or clinics
You may not qualify if:
- Those who did not want to participant
- The infant was dead at the birth
- Those pregnant mothers who dropped out during follow-up at pregnancy or moved out of the Jiaxing area
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Zhejiang Universitylead
- Jiaxing Maternity and Child Health Care Hospitalcollaborator
- Qingdao Universitycollaborator
- Westlake Universitycollaborator
Study Sites (1)
Zhejiang University
Hangzhou, Zhejiang, 310058, China
Related Publications (1)
Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Cohort Profile: The Jiaxing Birth Cohort in China. Int J Epidemiol. 2017 Oct 1;46(5):1382-1382g. doi: 10.1093/ije/dyw203. No abstract available.
PMID: 27940484BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
June 18, 2017
First Posted
July 14, 2017
Study Start
January 1, 1999
Primary Completion
January 1, 2019
Study Completion (Estimated)
January 1, 2029
Last Updated
January 23, 2018
Record last verified: 2018-01