the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai
shapd-woq
1 other identifier
observational
1,480
1 country
1
Brief Summary
The study would be designed as a multi-center cross-sectional investigation on the prevalence of Wearing-off in Parkinson's patients in Shanghai as well as related influencing factors.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2017
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2017
CompletedFirst Submitted
Initial submission to the registry
July 22, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2018
CompletedFirst Posted
Study publicly available on registry
January 3, 2019
CompletedJanuary 3, 2019
July 1, 2018
12 months
July 22, 2018
January 1, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
the prevalence of wearing off effect in Parkinson's patients that received stable anti Parkinsonian therapy in Shanghai of China
every participant receives a clinical assessment of the wearing-off symptoms by a physician and completes a self rating scale of the wearing-off 9 questionnaire (WOQ-9) to obtain a prevalence of wearing-off positive individuals( wearing-off would be diagnosed by physicians during the clinical assessments)
1 year
Secondary Outcomes (2)
the sensitivity and the specificity of the wearing-off 9 questionnaire in the diagnosis of wearing-off effect in Parkinson's disease.
1 year
the risk factors of wearing-off in Parkinson disease
1 year
Study Arms (1)
PD patients with wearing-off effect
people who have been clinically diagnosed with Parkinson's disease (PD) and have received anti PD therapy would be recruited into the study. The anti -PD treatment would not be changed in the population of the participants. We would use the tool of 'Wearing-off 9 questionnaire' to determine the prevalence of Wearing-off phenomenon in Parkinson's patients in Shanghai
Interventions
The participants would receive appropriate anti-PD medical treatments according to the patients' need during the investigation.The anti -PD treatment would not be changed in the population of the participants.
Eligibility Criteria
clinical diagnosed PD patients
You may qualify if:
- have been clinical diagnosed with Parkinson's disease
- have received stable anti-Parkinson's treatment before being recruited to the study.
You may not qualify if:
- being suspicious of atypical Parkinson syndrome or secondary Parkinson syndromes
- have not received anti Parkinsonian treatment.
- being combined with serious cognitive dysfunction or psychiatric symptoms
- unable to complete the investigations.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Xinhua hospital affiliated to Shanghai jiaotong university school of medicine
Shanghai, Shanghai Municipality, 200092, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Zhenguo Liu, Ph.D.
Xinhua hosipital affiliated to Shanghai Jiaotong university school of medicine
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 22, 2018
First Posted
January 3, 2019
Study Start
September 1, 2017
Primary Completion
August 31, 2018
Study Completion
August 31, 2018
Last Updated
January 3, 2019
Record last verified: 2018-07