Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery
Rectus
Respiratory Effects of Rectus Sheath Block in Patients Undergoing Major Upper Abdominal Surgery.
1 other identifier
interventional
60
1 country
1
Brief Summary
This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2020
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 29, 2018
CompletedFirst Posted
Study publicly available on registry
October 31, 2018
CompletedStudy Start
First participant enrolled
May 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2026
CompletedSeptember 4, 2025
August 1, 2025
5.7 years
September 29, 2018
August 27, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Diaphragmatic inspiratory amplitude during quiet/deep breathing (DIA)/cm
The ultrasonic measurements of diaphragmatic motion will be attained at the posterior surface of the diaphragm. From the tracings on M-mode, the distance between echogenic lines (DIA) in centimeters and diaphragmatic inspiratory/expiratory velocity in centimeters/second during quiet, deep, and sniff breathing will be measured on the frozen images.
24 hours Postoperative
Secondary Outcomes (2)
Verbal Rating Scale
24 hours Postoperatively
Forced Vital Capacity/L
24 hours Postoperatively
Study Arms (2)
Rectus sheath block
ACTIVE COMPARATORPatients will receive ultrasound-guided rectus sheath block' performed after induction of general anesthesia and before surgery.
control
NO INTERVENTIONPatients will receive general anesthesia .
Interventions
Sonar guided RSB will be performed using a 16-G, 8-cm TuohyUpon reaching this potential space, after careful aspiration.
Eligibility Criteria
You may qualify if:
- Age: 18-50 years.
- Sex: both males and females.
- BMI\< 30kg/m2.
- ASA physical status: 1, II and III.
- Elective abdominal surgery with midline incisions.
You may not qualify if:
- Patient refusal.
- Infection at injection site
- Coagulation disorders.
- Allergy to study medications.
- Pregnancy.
- Respiratory tract infection within the last 2 weeks.
- Urgent abdominal surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut university main hospital, ICUs
Asyut, Assiut Governorate, 715715, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Noha Y Mohamed, MD
Lecturer in anesthesia and intensive care department, faculty of medicine, Assiut university, Egypt.
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Masking Details
- double blinded
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of anesthesia and intensive care, faculty of medicine, Assiut university.
Study Record Dates
First Submitted
September 29, 2018
First Posted
October 31, 2018
Study Start
May 1, 2020
Primary Completion
January 1, 2026
Study Completion
January 1, 2026
Last Updated
September 4, 2025
Record last verified: 2025-08
Data Sharing
- IPD Sharing
- Will not share