NCT05833048

Brief Summary

This is a prospective, randomized study. The purpose of this study is to evaluate the effect of post-surgical pain control of a type of peripheral nerve block, Rectus Sheath Block.

  1. 1.Does the rectus sheath block decrease opioid consumption postoperatively after cardiac surgery?
  2. 2.Does the rectus sheath block decrease VAS pain scores postoperatively after cardiac surgery? Study participants will be assigned to receive either rectus sheath block or no block.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
4mo left

Started Jul 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress84%
Jul 2024Sep 2026

First Submitted

Initial submission to the registry

April 17, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

April 27, 2023

Completed
1.3 years until next milestone

Study Start

First participant enrolled

July 29, 2024

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2026

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 7, 2026

Expected
Last Updated

September 23, 2025

Status Verified

September 1, 2025

Enrollment Period

1.7 years

First QC Date

April 17, 2023

Last Update Submit

September 18, 2025

Conditions

Keywords

cardiac surgeryregional anesthesia

Outcome Measures

Primary Outcomes (2)

  • Opioid consumption

    Amount of opioid consumption required postoperatively

    72 hours postoperatively

  • VAS pain scores

    VAS pain scores (1-10, 1 being no pain and 10 being worst pain) recorded postoperatively

    72 hours postoperatively

Secondary Outcomes (3)

  • Length of stay in ICU

    72 hours

  • Length of hospital stay

    72 hours

  • Time to extubation

    72 hours

Study Arms (2)

Rectus Sheath Block

EXPERIMENTAL
Procedure: Rectus sheath block

No block

NO INTERVENTION

Interventions

Participants will receive an ultrasound guided rectus sheath block with local anesthetic

Rectus Sheath Block

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • Adults 18-85 years old
  • Scheduled to undergo cardiac procedures involving chest tubes
  • Male or female

You may not qualify if:

  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • ASA class V
  • Urgent or emergent surgery
  • Contraindications to administration of local anesthesia (e.g. local anesthetic allergy)
  • History of substance abuse or chronic opioid use
  • Patient refusal or inability to consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mount Sinai Morningside Hospital Center

New York, New York, 10023, United States

RECRUITING

MeSH Terms

Conditions

Heart DiseasesPain, Postoperative

Condition Hierarchy (Ancestors)

Cardiovascular DiseasesPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Anesthesiology

Study Record Dates

First Submitted

April 17, 2023

First Posted

April 27, 2023

Study Start

July 29, 2024

Primary Completion

March 30, 2026

Study Completion (Estimated)

September 7, 2026

Last Updated

September 23, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations