NCT03680768

Brief Summary

The purpose of this cross-sectional study is to collect relevant molecular markers of aging and measures of physiological function. Together these biomarkers are used to develope a new Biological Age model, useful in health promotion interventions in the public health sector .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 21, 2018

Completed
18 days until next milestone

Study Start

First participant enrolled

October 9, 2018

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 20, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2019

Completed
Last Updated

February 19, 2020

Status Verified

February 1, 2020

Enrollment Period

1.2 years

First QC Date

September 17, 2018

Last Update Submit

February 18, 2020

Conditions

Keywords

HealthRisk of diseasePredictionLifestyle

Outcome Measures

Primary Outcomes (1)

  • Biological Age

    A composite score of ones biological state (in years)

    Day 1

Secondary Outcomes (21)

  • Fitness Level

    Day 0

  • Strength

    Day 0

  • Sit to Stand test

    Day 0

  • Central obesity

    Day 0

  • Weight

    Day 0

  • +16 more secondary outcomes

Interventions

The protocol includes measurements of body composition, strength test, functional and fitness test as well as biochemical measurements from blood samples and AGEreader

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Sample size representing the general healthy danish population

You may qualify if:

  • Males and females interested in their personal health status
  • Healthy males and females

You may not qualify if:

  • Pregnancy
  • Previous or current cardiovascular disease
  • Use of medication that affects our measurements such as betablockers,statins or medication that affects the metabolism.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Copenhagen, Department of Biomedical Sciences

Copenhagen, 2200, Denmark

Location

Related Publications (2)

  • Husted KLS, Brink-Kjaer A, Fogelstrom M, Hulst P, Bleibach A, Henneberg KA, Sorensen HBD, Dela F, Jacobsen JCB, Helge JW. A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study. JMIR Aging. 2022 May 10;5(2):e35696. doi: 10.2196/35696.

  • Husted KLS, Fogelstrom M, Hulst P, Brink-Kjaer A, Henneberg KA, Sorensen HBD, Dela F, Helge JW. A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development. JMIR Res Protoc. 2020 Oct 26;9(10):e19209. doi: 10.2196/19209.

Biospecimen

Retention: SAMPLES WITH DNA

Blood sample will be drawn from a vein in the elbow

Study Officials

  • Jørn W Helge, Prof

    Biomedicinsk Institut

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ph.D., Proffesor Jørn Wulff Helge

Study Record Dates

First Submitted

September 17, 2018

First Posted

September 21, 2018

Study Start

October 9, 2018

Primary Completion

December 20, 2019

Study Completion

December 20, 2019

Last Updated

February 19, 2020

Record last verified: 2020-02

Locations