Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

NCT03180814 | Completed

• 1 other identifier: WBV on autonomic function
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Conditions

Healthy; Aging

Outcome Measures

Primary Outcomes (1)

• Autonomic Function

  Heart rate variability will be assessed from 3-channel holter

  Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes

Secondary Outcomes (7)

• Sympathetic modulation

  Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes

• Parasympathetic modulation

  Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes

• Sympathovagal Balance

  Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes

• Heart Rate

  Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes

• Blood pressure

  Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes

Study Arms (2)

Young Group

ACTIVE COMPARATOR

Healthy young of both sexes between the ages of 18 and 30 years will perform a whole body vibration session

Other: Whole Body Vibration

Elderly Group

EXPERIMENTAL

Healthy elderly of both sexes between the ages of 60 and 80 years will perform a whole body vibration session

Other: Whole Body Vibration

Interventions

Whole Body Vibration OTHER

A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.

Elderly Group; Young Group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Elderly individuals aged between 60 and 80 years
• Young individuals aged between 18 and 30 years
• Able to walk without assistance
• Good understanding to perform the proposed procedures
• Sedentary or low active

You may not qualify if:

• Body Mass Index (BMI) \> 35Kg/m2
• Systolic blood pressure \> 140 mmHg or diastolic blood pressure \> 90 mmHg (at rest)
• Difficulty adapting to the whole body vibration
• Smoking
• Neuromuscular or degenerative disorders
• Neurological diseases
• Cardiopulmonary comorbidities
• Cardiac arrhythmias
• Osteoarticular disorders
• Use of hormone replacement therapy
• Use medications or supplements known to affect cardiovascular parameters
• Labyrinthitis

Sponsors & Collaborators

• Universidade Federal de Pernambuco: lead

Study Sites (1)

Federal University of Pernambuco

Recife, Pernambuco, Brazil

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Msc

Study Record Dates

• First Submitted: March 21, 2017
• First Posted: June 8, 2017
• Study Start: July 31, 2017
• Primary Completion: August 31, 2017
• Study Completion: December 30, 2017
• Last Updated: January 3, 2018

Record last verified: 2017-12

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)