Glycemic and Insulinemic Response of Pasta Products in Comparison to Asian Foods
1 other identifier
interventional
32
1 country
1
Brief Summary
The aim of the study is to determine the glycaemic and insulinaemic index of pasta products and local foods. It is hypothesized that different pasta cuts and wholegrain composition of pasta and local foods have different GI depending on the nature of the carbohydrate content and the food structure within each food.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable diabetes
Started Aug 2018
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 10, 2018
CompletedFirst Submitted
Initial submission to the registry
August 23, 2018
CompletedFirst Posted
Study publicly available on registry
August 24, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2020
CompletedAugust 31, 2023
August 1, 2023
1.8 years
August 23, 2018
August 29, 2023
Conditions
Outcome Measures
Primary Outcomes (2)
Glucose
Blood will be collected and measured using hemocue analyzer.
up to 180 minutes
Insulin
Blood will be collected and measured using COBAS analyzer.
up to 180 minutes
Study Arms (9)
Glucose Reference 1
OTHER50g of glucose dissolved in 250ml of water to be consumed.
Glucose Reference 2
OTHER50g of glucose dissolved in 250ml of water to be consumed.
Glucose Reference 3
OTHER50g of glucose dissolved in 250ml of water to be consumed.
Semolina Penne
EXPERIMENTAL70g of semolina penne boiled in 1 Litre of water for 11 minutes. Drained and consume immediately.
Wholegrain Penne
EXPERIMENTAL76g of wholegrain penne boiled in 1 Litre of water for 9 minutes. Drained and consume immediately.
Semolina Spaghetti
EXPERIMENTAL71g of semolina spaghetti boiled in 1 Litre of water for 8 minutes. Drained and consume immediately.
Wholegrain Spaghetti
EXPERIMENTAL76g of wholegrain spaghetti boiled in 1 Litre of water for 8 minutes. Drained and consume immediately.
Jasmine rice
EXPERIMENTAL63g of rice cook with 150g of water. Served and consume immediately.
Asian Noodles
EXPERIMENTAL92.4g of Asian Noodles cook in boiling water for 45 seconds. Drained and consume immediately
Interventions
Wholegrain Spaghetti contains 50g of available carbohydrates
Eligibility Criteria
You may qualify if:
- Healthy Asian - Indian and Chinese ethnicity
- Age between 21-40 years
- Body mass index between 18.5 to 25 kg/m2
- Normal blood pressure (\<140/90 mmHg)
- Fasting blood glucose \< 6 mmol/L
You may not qualify if:
- Is a current smoker
- Is currently pregnant
- Have any metabolic diseases (such as diabetes, hypertension etc)
- Have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
- Have medical conditions and/or taking medications known to affect glycemia(glucocorticoids, thyroid hormones, thiazide diuretics)
- Have any major organ dysfunction (e.g. cardiovascular, respiratory, hepatic, renal, gastrointestinal) that may influence taste, olfaction, appetite, digestion, metabolism, absorption or elimination of test foods, nutraceutical or drug
- Have any severe food allergy (e.g. anaphylaxis to peanuts)
- Have any known allergies to any food components of the study protocol
- Have active Tuberculosis (TB) or currently receiving treatment for TB
- Have any known Chronic infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)
- Is a study team member or an immediate family of any study team member. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted.
- enrolled in a concurrent research study judged not to be scientifically or medically compatible with the study.
- Have partake in sports at the competitive and/or endurance levels
- Have intentionally restrict food intake
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Clinical Nutrition Research Centre
Singapore, 117599, Singapore
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 23, 2018
First Posted
August 24, 2018
Study Start
August 10, 2018
Primary Completion
June 1, 2020
Study Completion
June 1, 2020
Last Updated
August 31, 2023
Record last verified: 2023-08
Data Sharing
- IPD Sharing
- Will not share