NCT05203575

Brief Summary

Effective control of diabetes requires patients to change their daily behaviour. The investigators propose an intervention programme for behavioural change with two components, targeting motivation and implementation. The motivation component raises the salience of probable patient-specific detrimental future outcomes by 'fast-forwarding' awareness of these outcomes to the present. The implementation component helps patients to set goals and to act based on weekly tips. A factorial design will be used to establish the necessity and sufficiency of the two components on changing mind and guiding behaviour to improve blood glucose level. Individual-level measures of psychological, physical and medical conditions will be shown to drive the heterogenous responses to the two components. Intervention is expanded into two cycles with crossover design to demonstrate how the individual-level measures drive the wear-off, built-up and persistence of the two components. The results of this two-component programme will serve as a basis for systematic synthesis of component-level effectiveness in behavioural intervention research.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
225

participants targeted

Target at P50-P75 for not_applicable diabetes

Timeline
Completed

Started Mar 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 2, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 24, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

March 28, 2022

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

September 28, 2022

Status Verified

September 1, 2022

Enrollment Period

1.4 years

First QC Date

December 2, 2021

Last Update Submit

September 27, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • HbA1c after Cycle 1

    Results from HbA1c test

    Measured between Weeks 17-18

  • HbA1c after Cycle 2

    Results from HbA1c test

    Measured between Weeks 33-34

Secondary Outcomes (14)

  • Diet quality after Cycle 1

    Measured between Weeks 17-18

  • Diet quality after Cycle 2

    Measured between Weeks 33-34

  • Exercise levels after Cycle 1

    Measured between Weeks 17-18

  • Exercise levels after Cycle 2

    Measured between Weeks 33-34

  • Attitudes towards diabetes management after Cycle 1

    Measured between Weeks 17-18

  • +9 more secondary outcomes

Study Arms (10)

Control

NO INTERVENTION

Control condition

Weekly nudge in Cycle 2

EXPERIMENTAL

Weekly nudge intervention in Cycle 2

Behavioral: Goal-Setting plus Weekly Nudge in Cycle 2

Fast-forwarding

EXPERIMENTAL

Fast-forwarding interventions in both Cycles

Behavioral: Fast-forwarding in Cycle 1Behavioral: Fast-forwarding in Cycle 2

Fast-forwarding with weekly nudge in Cycle 2

EXPERIMENTAL

Fast-forwarding interventions in both Cycles, plus weekly nudge intervention in Cycle 2

Behavioral: Fast-forwarding in Cycle 1Behavioral: Fast-forwarding in Cycle 2Behavioral: Goal-Setting plus Weekly Nudge in Cycle 2

Weekly nudge in Cycle 1

EXPERIMENTAL

Weekly nudge intervention in Cycle 1

Behavioral: Goal-Setting plus Weekly Nudge in Cycle 1

Weekly nudge

EXPERIMENTAL

Weekly nudge interventions in both Cycles

Behavioral: Goal-Setting plus Weekly Nudge in Cycle 1Behavioral: Goal-Setting plus Weekly Nudge in Cycle 2

Fast-forwarding with weekly nudge in Cycle 1

EXPERIMENTAL

Fast-forwarding interventions in both Cycles, plus weekly nudge intervention in Cycle 1

Behavioral: Fast-forwarding in Cycle 1Behavioral: Goal-Setting plus Weekly Nudge in Cycle 1Behavioral: Fast-forwarding in Cycle 2

Full intervention

EXPERIMENTAL

All interventions applied in all Cycles

Behavioral: Fast-forwarding in Cycle 1Behavioral: Goal-Setting plus Weekly Nudge in Cycle 1Behavioral: Fast-forwarding in Cycle 2Behavioral: Goal-Setting plus Weekly Nudge in Cycle 2

Fast-forwarding in Cycle 1

EXPERIMENTAL

Fast-forwarding intervention in Cycle 1

Behavioral: Fast-forwarding in Cycle 1

Full in Cycle 1

EXPERIMENTAL

Fast-forwarding and weekly nudge interventions in Cycle 1

Behavioral: Fast-forwarding in Cycle 1Behavioral: Goal-Setting plus Weekly Nudge in Cycle 1

Interventions

The fast-forwarding intervention will consist of a projection of future risk of co-morbidities. A visual projection model will be built using archival data available through the Singapore Diabetes Registry. The projection model will use the current profile of the participant to calculate a risk profile for the participant's potential complications and co-morbidities, which will be presented as a pie chart. The tool will also present alternative scenarios to the participant and visualize how the likelihood of complications or co-morbidities would decrease or increases if his/her habits changed. This will provide the motivational aspect of the intervention. This intervention takes place during Cycle 1 (first 14 weeks).

Fast-forwardingFast-forwarding in Cycle 1Fast-forwarding with weekly nudge in Cycle 1Fast-forwarding with weekly nudge in Cycle 2Full in Cycle 1Full intervention

The procedure for goal-setting will start with the participant receiving a list of possible goals. The moderator will go through the list with the participant to identify which goals the participant is comfortable with and could reasonably achieve, and to tick off those goals that the participant has already achieved. The participants will choose their own goals. In each subsequent week, the moderator will check-in with the participant and tick off the goal(s) that have been achieved. Chat groups of 10-15 people will be formed to administer the weekly nudge. The participants will be encouraged to introduce themselves and to interact with each other during each the chat session. Every week for the following 14 weeks, the moderator will post diabetes-related content on the WhatsApp chat group and introduce topics of interest according to a planned schedule. This intervention takes place during Cycle 1 (first 14 weeks).

Fast-forwarding with weekly nudge in Cycle 1Full in Cycle 1Full interventionWeekly nudgeWeekly nudge in Cycle 1

The fast-forwarding intervention will consist of a projection of future risk of co-morbidities. A visual projection model will be built using archival data available through the Singapore Diabetes Registry. The projection model will use the current profile of the participant to calculate a risk profile for the participant's potential complications and co-morbidities, which will be presented as a pie chart. The tool will also present alternative scenarios to the participant and visualize how the likelihood of complications or co-morbidities would decrease or increases if his/her habits changed. This will provide the motivational aspect of the intervention. This intervention takes place during Cycle 2 (second 14 weeks).

Fast-forwardingFast-forwarding with weekly nudge in Cycle 1Fast-forwarding with weekly nudge in Cycle 2Full intervention

The procedure for goal-setting will start with the participant receiving a list of possible goals. The moderator will go through the list with the participant to identify which goals the participant is comfortable with and could reasonably achieve, and to tick off those goals that the participant has already achieved. The participants will choose their own goals. In each subsequent week, the moderator will check-in with the participant and tick off the goal(s) that have been achieved. Chat groups of 10-15 people will be formed to administer the weekly nudge. The participants will be encouraged to introduce themselves and to interact with each other during each the chat session. Every week for the following 14 weeks, the moderator will post diabetes-related content on the WhatsApp chat group and introduce topics of interest according to a planned schedule. This intervention takes place during Cycle 2 (second 14 weeks).

Fast-forwarding with weekly nudge in Cycle 2Full interventionWeekly nudgeWeekly nudge in Cycle 2

Eligibility Criteria

Age21 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age between 21-70
  • Has type 2 diabetes
  • Comfortable communicating English
  • Uses smartphone app WhatsApp

You may not qualify if:

  • Participants with diagnoses of mental health illnesses
  • Participants who are unable to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National University of Singapore

Singapore, Singapore

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

December 2, 2021

First Posted

January 24, 2022

Study Start

March 28, 2022

Primary Completion

August 31, 2023

Study Completion

August 31, 2023

Last Updated

September 28, 2022

Record last verified: 2022-09

Data Sharing

IPD Sharing
Will share

Investigators will not be storing or sharing any personal identifiers. All individual level data will be anonymized, and only anonymized data will be shared with other researchers, upon request.

Shared Documents
STUDY PROTOCOL, ANALYTIC CODE
Time Frame
The supporting information will be made available upon publication in the supporting documentation.
Access Criteria
It will be made available in the supporting documentation.

Locations