NCT03629119

Brief Summary

The purpose of this pilot study is to assess the feasibility of a 3-month dietary fiber intervention: 1) engaging adolescents in regularly consuming a dietary fiber preparation (psyllium powder) and obtaining their parents' support, 2) recruit into a clinical pilot trial with liquid meal challenge test to study the metabolic effects of the dietary fiber preparation. A study modification will be submitted to add additional study arms for feasibility (strength training, coaching).

Trial Health

33
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Trial recruitment is currently suspended
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Jul 2019

Typical duration for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 9, 2018

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 14, 2018

Completed
12 months until next milestone

Study Start

First participant enrolled

July 31, 2019

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

January 18, 2022

Status Verified

January 1, 2022

Enrollment Period

3.3 years

First QC Date

August 9, 2018

Last Update Submit

January 6, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Recruitment

    Proportion of patients recruited/consented

    3 year recruitment period

  • Retention

    Proportion of participants remaining in study

    3-mo study period

Study Arms (1)

Dietary Fiber Supplement

EXPERIMENTAL

Participants will be instructed to consume 1 tea spoon of psyllium per day for 3 months and otherwise maintain their habitual diet.

Dietary Supplement: Dietary Fiber Supplement

Interventions

Dietary Fiber SupplementDIETARY_SUPPLEMENT

Participants will be instructed to consume 1 tea spoon of psyllium per day for 3 months and otherwise maintain their habitual diet. Participants will be asked to keep a diary assessing bowel movement and intestinal symptoms such as bloating and flatulence beginning two weeks prior to the intervention.

Dietary Fiber Supplement

Eligibility Criteria

Age12 Years - 21 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Kaiser Permanente Southern California (KPSC) member for at least 12 months.
  • KPSC members ages 12 to 21 years old.
  • KPSC member with \>97th percentile of BMI for age.
  • Minors with parents whose preferred language is English.
  • to 21 year old members whose preferred language is English.

You may not qualify if:

  • Has diagnosis of serious mental illness and/or cognitive impairment.
  • Provider has concerns over participation.
  • Minors with parent whose preferred language is not English.
  • to 21 year old members whose preferred language is not English.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kaiser Permanente Clinical Research Center

Pasadena, California, 91101, United States

Location

MeSH Terms

Conditions

ObesityPediatric Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 9, 2018

First Posted

August 14, 2018

Study Start

July 31, 2019

Primary Completion

December 1, 2022

Study Completion

December 1, 2022

Last Updated

January 18, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations