Training With Exergame and Treadmill on Executive Function and Dual-task Performance

NCT03623841 | Completed

• 1 other identifier: 17MMHIS193
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to investigate the effects of dual-task training with exergame and treadmill on executive function and dual-task performance in individuals with PD and stroke and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.

Conditions

Parkinson's Disease; Stroke

Keywords

Executive function; Dual-task performance; Dual-task training

Outcome Measures

Primary Outcomes (1)

• Dual-task walking performance

  To evaluate gait parameters while doing dual-task walking

  Change from baseline at 8 weeks

Secondary Outcomes (10)

• Single walking performance

  Change from baseline at 8 weeks

• Timed up and go test

  Change from baseline at 8 weeks

• Parkinson's Disease Questionnaire 39

  Change from baseline at 8 weeks

• Frontal lobe battery test-Chinese version

  Change from baseline at 8 weeks

• Trail-making test

  Change from baseline at 8 weeks

Study Arms (2)

Dual-task training group

EXPERIMENTAL

Participants in dual-task training group will execute dual-task training via exer-game which combined with treadmill, 3 times per week, least 8 weeks.

Other: Dual-task training

Treadmill training group

ACTIVE COMPARATOR

Participants in treadmill training group will do treadmill training only, 3 times per week, least 8 weeks.

Other: Treadmill training

Interventions

Dual-task training OTHER

Participants in experimental group will do dual-task training via exer-game which combined with treadmill

Dual-task training group

Treadmill training OTHER

Participants in control group will do treadmill training only

Treadmill training group

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed as PD and Hoehn and Yahr stage between 1\~3
• Age between 50 to 80
• Able to walk 10 m independently without an assistive device
• A score of greater than or equal to 24 on the mini-mental state examination (MMSE)
• In stable medical condition allowing participation in the testing protocol and intervention

You may not qualify if:

• Any comorbidity or disability other than PD that would preclude gait training
• Any uncontrolled health condition for which exercise was contraindicated
• Any neurological or orthopedic disease that might interfere with the study
• Server freezing of gait, FOG questionnaire \> 15

Sponsors & Collaborators

• National Yang Ming Chiao Tung University: lead

Study Sites (1)

National Yang-Ming university

Taipei, 112, Taiwan

Location

Related Publications (1)

• Zhou JH, Wang RY, Liu YT, Cheng SJ, Liu HH, Yang YR. Effects of dual-task training on gait variability in individuals with Parkinson's disease: A randomized controlled trial. J Sci Med Sport. 2025 Dec;28(12):1012-1018. doi: 10.1016/j.jsams.2025.06.009. Epub 2025 Jun 20.

  PMID: 40610273 DERIVED

MeSH Terms

Conditions

Parkinson Disease; Stroke

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Cerebrovascular Disorders; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: July 29, 2018
• First Posted: August 9, 2018
• Study Start: November 9, 2018
• Primary Completion: June 30, 2022
• Study Completion: August 9, 2022
• Last Updated: July 9, 2024

Record last verified: 2024-07

Locations

TW (1)