Multi-task Gait Training Mode to Enhance Walking Function in Patients With Chronic Stroke

NCT04328779 | Completed

• 1 other identifier: ChangGungU
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of multi-task walking interventions on walking for patients with chronic stroke. Specifically, we will investigate psychometric properties (i.e. reliability, validity, and responsiveness) of dual-task walking assessments with the Stroop task for chronic stroke individuals (Aim 1). The second aim of this study is to compare the effects of multi-task walking training mode to traditional rehabilitation in patients with chronic stroke (Aim 2). The third aim of this study is to compare the immediate, retained, and transfer effect of multi-task overground walking training to multi-task treadmill walking training on walking function, cognitive performance, task coordination, and community ambulation in patients with chronic stroke (Aim 3).

Conditions

Stroke

Keywords

multi-task training; community ambulation; cognition

Outcome Measures

Primary Outcomes (2)

• gait speed

  Participants will walk 10m at their preferred speed and at fast speed. A 12-meter walkway will be used for walking testing. In order to allow the subjects to have enough distance to accelerate and decelerate, only the time taken to walk the middle 10 meters will be recorded by a stopwatch or Physilog® sensors (Gait Up, Switzerland). The primary gait parameter is gait speed (cm/s) under single-task and dual-task walking conditions using the 10 Meter Walking Test.

  5 minutes

• composite score

  For the Stroop task, we will calculate the composite score for the Stroop task under single-task and dual-task walking conditions by dividing the accuracy (% correct responses) with the reaction time of correct answers (milliseconds), which accounts for speed-accuracy tradeoffs.

  5 minutes

Secondary Outcomes (8)

• Mini-Balance Evaluation Systems Test (Mini-BESTest)

  10 minutes

• Timed Up and Go Test (TUG)

  2 minutes

• Functional Gait Assessment (FGA)

  10 minutes

• Berg Balance Scale (BBS)

  5-10 minutes

• 6-minute Walk Test

  6 minutes

Study Arms (3)

multi-task overground walking training

EXPERIMENTAL

The multi-task overground walking training group will undertake overground walking training while concurrently perform motor and cognitive tasks.

Other: The multi-task overground walking training

multi-task treadmill walking

ACTIVE COMPARATOR

The multi-task treadmill walking training group will train the same set of motor and cognitive tasks while walking on the treadmill.

Device: The multi-task treadmill walking training

traditional rehabilitation

ACTIVE COMPARATOR

Traditional rehabilitation group will train strength, balance, and gait.

Other: Traditional rehabilitation

Interventions

The multi-task overground walking training OTHER

The multi-task overground walking training group will undertake overground walking training while concurrently perform motor and cognitive tasks for 30 minutes per session, 3 times a week for 4 weeks.

multi-task overground walking training

The multi-task treadmill walking training DEVICE

The multi-task treadmill walking training group will train the same set of motor and cognitive tasks while walking on the treadmill for 30 minutes per session, 3 times a week for 4 weeks.

multi-task treadmill walking

Traditional rehabilitation OTHER

Traditional rehabilitation will train strength, balance, and gait for 30 minutes per session, 3 times a week for 4 weeks.

traditional rehabilitation

Eligibility Criteria

• Age: 20 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• first-ever stroke with onset duration more than 3 months
• able to walk 10 m
• no severe vision, hearing, and language problems.

You may not qualify if:

• orthopedic and other neurological disorders that affect walking
• other treatments that could influence the effects of the interventions (e.g., recent Botulin toxin treatment of the lower extremity)
• moderate or severe cognitive impairments (score \< 24 on Mini-Mental State Examination)
• severe uncorrected visual deficits.

Sponsors & Collaborators

• Chang Gung University: lead

Study Sites (1)

Mackay Memory Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Li-Ling Chuang, Ph.D.

  Chang Gung University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associated Professor

Study Record Dates

• First Submitted: March 30, 2020
• First Posted: March 31, 2020
• Study Start: August 14, 2020
• Primary Completion: October 31, 2023
• Study Completion: October 31, 2023
• Last Updated: February 7, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)