NCT04040101

Brief Summary

Background: Stroke is the 4th deadly disease in Taiwan, 2016. Long term disabilities, balance impairments and limitations of activities of daily living are common characteristics of stroke. Balance assessment and training play an important role in stroke rehabilitation. However, there are some limitations. Clinical assessments (functional scales) could not avoid some errors caused by subjective observations from different test givers; instrumental assessments (force plates, Biodex system) are complex to approach, not easy to use, and difficult to get. Balance training could not meet the expected effectiveness due to inconvenient transportations, forgotten home programs, and time limitation caused by huge amount of patients with insufficient therapists. Smartphones had been used for health promoting and sport training. The balance training related applications could be found at Google Play store, but clinically proved effective App and stroke-designed App has not yet existed. The balance rehabilitation of stroke sufferers will be benefited if there is an easy-use and effective App that supports balance assessment and personalized training by combining the convenience and powerfulness of smartphones. Purpose: The purposes of this study are: Year 1 Develop a smartphone-based application to assess and train static balance for stroke sufferers, and evaluate the feasibility of the application; Year 2 Develop a smartphone-based application to assess and train dynamic balance for stroke sufferers, and evaluate the feasibility of the application; Year 3 Build a static and dynamic balance performance standard by recruiting healthy subjects, then evaluate the training effects of the application on balance performance of stroke sufferers. Methods: Android smartphones will be used to analyze the balance performance by collecting acceleration and angular velocity data from the built-in sensors. Static balance assessment and training system will be developed in the first year. The system will assess balance ability by testing the performance under different standing conditions, then provide a training plan according to the assessment result. Dynamic balance assessment and training system will be developed in the second year. The system will execute limits of stability test to assess dynamic balance, then provide a training plan according to the assessment result. Validity and reliability will be tested in the first and second year, by comparing the smartphone assessment result with Berg balance scale, force plate, and Biodex balance system. In the third year, we will recruit healthy subjects to create a balance performance standard, then recruit chronic stroke subjects to evaluate the training effect of the App by comparing with traditional rehabilitation therapy. Expected Results \& Contribution When the study is completed, several valuable contributions will be provided. These include (1) developing a smartphone application which can be used to assess and rehabilitate static and dynamic balance functions on stroke sufferers; (2) evaluating the feasibility and the training effects of the smartphone application, and providing evidence-based results for scientific paper publication; (3) clinically offering an easy-used and effective tool for clinicians and subjects with stroke to evaluate and improve balance performance.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started May 2018

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 23, 2018

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

July 14, 2019

Completed
17 days until next milestone

First Posted

Study publicly available on registry

July 31, 2019

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2022

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

July 12, 2022

Status Verified

April 1, 2022

Enrollment Period

4.1 years

First QC Date

July 14, 2019

Last Update Submit

July 10, 2022

Conditions

Outcome Measures

Primary Outcomes (3)

  • Balance performance assessed by smartphone-based balance test

    The data of smartphone built-in accelerometer and gyroscope will be measured and calculated

    4 weeks

  • Balance performance assessed by force plates

    The movement of center of pressure (COP) will be measured and calculated

    4 weeks

  • Balance performance assessed by Berg balance scale

    The score of Berg balance scale will be measured

    4 weeks

Study Arms (4)

Healthy Adult

NO INTERVENTION

balance assessment

Stroke

NO INTERVENTION

balance assessment

Stroke smartphone training

EXPERIMENTAL

smartphone balance training

Device: smartphone-based balance training system

Stroke traditional training

ACTIVE COMPARATOR

traditional physical therapy training

Device: smartphone-based balance training system

Interventions

use smartphone application to training balance

Also known as: traditional physical therapy
Stroke smartphone trainingStroke traditional training

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • stroke
  • Brunnstrom stage \> 4
  • able to walk independently indoors
  • able to follow order of the researchers

You may not qualify if:

  • have any diseases that may affect balance performance except stroke

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tri-Service General Hospital

Taipei, Neihu District, 11490, Taiwan

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • You-Ruei Hou, Master

    National Yang Ming Chiao Tung University

    STUDY CHAIR

Central Study Contacts

You-Ruei Hou, Master

CONTACT

Wen-Hsu Sung, Doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 14, 2019

First Posted

July 31, 2019

Study Start

May 23, 2018

Primary Completion

June 30, 2022

Study Completion

August 31, 2023

Last Updated

July 12, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations