Dual-task Performance in Young-onset PD
Decrement of the Dual-task Performance in Individuals With Young-onset Parkinson's Disease and the Training Effects
1 other identifier
interventional
40
0 countries
N/A
Brief Summary
This study aimed to investigate the effects of Game based dual-task training with treadmill on executive function and dual-task performance in individuals with early-onset PD and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Aug 2019
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 24, 2019
CompletedFirst Posted
Study publicly available on registry
July 26, 2019
CompletedStudy Start
First participant enrolled
August 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
July 31, 2022
CompletedJuly 29, 2019
July 1, 2019
3 years
July 24, 2019
July 25, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Dual-task walking performance
To evaluate gait parameters while doing dual-task walking
Change from baseline at 8 weeks
Secondary Outcomes (10)
Single walking performance
Change from baseline at 8 weeks
Timed up and go test
Change from baseline at 8 weeks
Parkinson's Disease Questionnaire 39
Change from baseline at 8 weeks
Frontal lobe battery test-Chinese version
Change from baseline at 8 weeks
Trail-making test
Change from baseline at 8 weeks
- +5 more secondary outcomes
Study Arms (2)
Game based dual-task training group
EXPERIMENTALParticipants in dual-task training group will execute game based dual-task training with treadmill, 3 times per week for 8 weeks
Treadmill training group
ACTIVE COMPARATORParticipants in treadmill training group will do treadmill training, 3 times per week for 8 weeks
Interventions
Participants in the experimental group will receive game based dual-task training with a treadmill
Participants in the control group will receive treadmill training
Eligibility Criteria
You may qualify if:
- Diagnosed as PD and Hoehn and Yahr stage between 1\~3
- Age between 20 to 80
- Able to walk 10 m independently without an assistive device
- A score of greater than or equal to 24 on the mini-mental state examination (MMSE)
- In stable medical condition allowing participation in the testing protocol and intervention
You may not qualify if:
- Any comorbidity or disability other than PD that would preclude gait training
- Any uncontrolled health condition for which exercise was contraindicated
- Any neurological or orthopedic disease that might interfere with the study
- Server freezing of gait, FOG questionnaire \> 15
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
July 24, 2019
First Posted
July 26, 2019
Study Start
August 1, 2019
Primary Completion
July 31, 2022
Study Completion
July 31, 2022
Last Updated
July 29, 2019
Record last verified: 2019-07