NCT03588728|TerminatedResultsDMC
Study Stopped
Lab was shut down due to COVID as were nearing study completion
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Lab was shut down due to COVID as were nearing study completion
TACTICSS
Sponsor study identifier
Secondary identifiers
NIH
interventional
39
1 country
1
Study Start
July 23, 2018
Actual (reported)Primary Completion
March 12, 2020
Actual (reported)Study Completion
March 12, 2020
Actual (reported)This study is being done to develop new methods to help smokers with schizophrenia to successfully reduce their smoking and/or quit. This is not a treatment study, but will help find new techniques to create better treatments. Specifically, the investigators are interested in learning more about how thoughts and attention problems associated with schizophrenia might play a role in smoking, as well as the impact of cognitive (thinking, reasoning, and remembering) training and brain stimulation on these symptoms and on actual smoking.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 12, 2020
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 3, 2018
Actual (reported)July 17, 2018
Actual (reported)July 23, 2018
Actual (reported)March 12, 2020
Actual (reported)March 12, 2020
Actual (reported)March 13, 2023
Actual (reported)Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS™): MATRICS Consensus Cognitive Battery (MCCB)
the MATRICS Consensus battery (MCCB) is a cognitive battery of tests for assessing cognition-enhancing treatments for schizophrenia through a broadly based scientific evaluation of measures. Change in cognitive measures of MATRICS Consensus Cognitive Battery (MCCB). Post-intervention minus baseline. Scale is scored 0-100. Difference score range is (-100 to 100) with positive scores reflecting improvement.
Baseline to approximately 4 weeks
Cue-Reactivity
Baseline to approximately 4 weeks
Cigarette Puff Volume
Baseline and at approximately 4 weeks
Latency to First Cigarette Puff
Baseline to approximately 4 weeks
AX Version of the Continuous Performance Task (AX-CPT) Reaction Time
Baseline to approximately 4 weeks
AX Version of the Continuous Performance Task (AX-CPT) Reaction Time Variability
Baseline to approximately 4 weeks
Cognitive Remediation (CR) and Transcranial Direct Current Stimulation (tDCS)
Cognitive Remediation (CR) and Sham Transcranial Direct Current Stimulation (tDCS)
Control Cognitive Remediation (CR) and Transcranial Direct Current Stimulation (tDCS)
Transcranial direct current stimulation targeting the right inferior frontal gyrus
Cognitive exercises on a computer designed to increase attention, memory, and processing speed.
University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, 15213, United States
Study was unexpectedly shut down prior to completing recruitment due to COVID-19 protocols.
Cynthia Conklin, PhD
University of Pittsburgh
39 participants (actual enrollment reported by the registry).
First Submitted
July 3, 2018
First Posted
July 17, 2018
Study Start
July 23, 2018
Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia
Control Cognitive Remediation (CR) and Sham Transcranial Direct Current Stimulation (tDCS)
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
March 12, 2020
Actual (reported)Study Completion
March 12, 2020
Actual (reported)Last Updated
March 13, 2023
Results First Posted
March 13, 2023
Record last verified: 2022-12
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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