Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity
BEETIT
1 other identifier
interventional
16
1 country
1
Brief Summary
The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2018
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 22, 2018
CompletedFirst Posted
Study publicly available on registry
June 4, 2018
CompletedStudy Start
First participant enrolled
August 10, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 30, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2020
CompletedSeptember 22, 2021
September 1, 2021
2.1 years
May 22, 2018
September 20, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Time to Exhaustion
A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit.
Study Arms (4)
Beetroot Juice
EXPERIMENTALBeetroot Juice no Nitrate
ACTIVE COMPARATORSodium Nitrate
ACTIVE COMPARATORControl
NO INTERVENTIONInterventions
70ml sodium nitrate, matched for nitrate concentration in Beetroot Juice arm
70ml Concentrated Beetroot Juice with nitrate removed
Eligibility Criteria
You may qualify if:
- BMI ≥ 30 kg/m2
- Able to perform exercise testing on a cycle ergometer
You may not qualify if:
- Currently taking medications know to affect cardiovascular or respiratory function
- Currently supplementing with an antioxidant compound
- Current smoker
- Currently taking antibiotics
- Not willing to abstain from mouthwash use
- Currently participating in regular physical activity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gordon Fisher, PhD
University of Alabama at Birmingham
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
May 22, 2018
First Posted
June 4, 2018
Study Start
August 10, 2018
Primary Completion
August 30, 2020
Study Completion
August 30, 2020
Last Updated
September 22, 2021
Record last verified: 2021-09
Data Sharing
- IPD Sharing
- Will not share