NCT03536832

Brief Summary

Subcuticular skin closure with suture after cesarean has been shown to result in lower rates of wound complications than with staple closure. However, the optimal choice of suture material for subcuticular skin closure is unclear. Vicryl vs Prolen suture materials will be used for subcuticular closure of transverse skin incisions after cesarean section. Patients will be controlled for superficial surgical site infections 1 week after the cesarean section.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
220

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 15, 2018

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

May 9, 2018

Completed
16 days until next milestone

First Posted

Study publicly available on registry

May 25, 2018

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2018

Completed
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2018

Completed
Last Updated

November 16, 2018

Status Verified

October 1, 2018

Enrollment Period

6 months

First QC Date

May 9, 2018

Last Update Submit

November 14, 2018

Conditions

Keywords

Cesarean Section; Complicationssuture material

Outcome Measures

Primary Outcomes (1)

  • surgical site infection

    infection

    1 week

Study Arms (2)

cesarean section with Vicryl

ACTIVE COMPARATOR

Women undergoing cesarean section with low transverse skin incisions will be closed with 3-0 Vicryl.

Procedure: Cesarean Section with Vicryl

cesarean section with prolene

ACTIVE COMPARATOR

Women undergoing cesarean section with low transverse skin incisions will be closed with 3-0 Prolen.

Procedure: Cesarean Section with Prolen

Interventions

Pfnannenstiel incision will be done under general or spinal anaesthesia. The abdomen will be opened and fetus and plasenta will be delivered. Then abdomen will be closed. Skin will be closed with Vicryl.

cesarean section with Vicryl

Pfnannenstiel incision will be done under general or spinal anaesthesia. The abdomen will be opened and fetus and plasenta will be delivered. Then abdomen will be closed. Skin will be closed with prolen.

cesarean section with prolene

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-40
  • women undergoing cesarean section

You may not qualify if:

  • body mass index\>30

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kanuni SSTRH

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Infections

Interventions

Cesarean SectionPolyglactin 910

Intervention Hierarchy (Ancestors)

Delivery, ObstetricObstetric Surgical ProceduresSurgical Procedures, OperativePolyestersPolymersMacromolecular SubstancesBiomedical and Dental MaterialsManufactured MaterialsTechnology, Industry, and Agriculture

Study Officials

  • Berna Aslan A Çetin

    KSSTRH

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Md, ObGYN

Study Record Dates

First Submitted

May 9, 2018

First Posted

May 25, 2018

Study Start

April 15, 2018

Primary Completion

October 15, 2018

Study Completion

November 1, 2018

Last Updated

November 16, 2018

Record last verified: 2018-10

Locations