Postoperative Acute Kidney Injury in Patients Undergoing Prolonged Neurosurgical Operations
1 other identifier
observational
100
0 countries
N/A
Brief Summary
Postoperative Acute Kidney Injury in Patients Undergoing Prolonged Neurosurgical Operations
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2018
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 22, 2018
CompletedFirst Posted
Study publicly available on registry
April 3, 2018
CompletedStudy Start
First participant enrolled
May 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
April 30, 2020
CompletedApril 3, 2018
March 1, 2018
2 years
March 22, 2018
March 27, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
the occurrence of AKI
BY using AKIN criteria.
2 days
Interventions
* Laboratory values will be obtained, including level of preoperative serum creatinine, complete blood count, coagulation profile and Cystatin-C (5 ml. venous sample). * Serum creatinine and hemoglobin will be measured after operation, and thereafter at least once a day as a part of routine clinical care. Postoperative serum Cystatin-C will measured only once.
Eligibility Criteria
patients aged 18 years or older
You may qualify if:
- patients aged 18 years or older who will do prolonged neurosurgical procedure, duration of surgery more than 4 hours and ASA 1-2-3.
You may not qualify if:
- refusal of consent, preexisting renal transplantation, preexisting nephrectomy, presence of AKI before neurosurgical procedure, operation less than 4 hours, patients aged under 18 years, pregnancy and ASA 4-5.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Deng Y, Yuan J, Chi R, Ye H, Zhou D, Wang S, Mai C, Nie Z, Wang L, Zhai Y, Gao L, Zhang D, Hu L, Deng Y, Chen C. The Incidence, Risk Factors and Outcomes of Postoperative Acute Kidney Injury in Neurosurgical Critically Ill Patients. Sci Rep. 2017 Jun 26;7(1):4245. doi: 10.1038/s41598-017-04627-3.
PMID: 28652590BACKGROUND
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 2 Days
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident
Study Record Dates
First Submitted
March 22, 2018
First Posted
April 3, 2018
Study Start
May 1, 2018
Primary Completion
April 30, 2020
Study Completion
April 30, 2020
Last Updated
April 3, 2018
Record last verified: 2018-03