NCT03465449

Brief Summary

The investigators are studying the feasibility, acceptability, and outcomes of an intervention called Enhanced Dialysis Education (EDU) Intervention. CKD-EDU is a palliative care-based dialysis decision-making intervention that involves educating patients and caregivers about dialysis and engaging them in shared decision-making. Half of the enrolled patients will receive CKD-EDU and the other half will receive Usual Care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 7, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 14, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

May 31, 2018

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 9, 2021

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2022

Completed
Last Updated

October 12, 2022

Status Verified

October 1, 2022

Enrollment Period

2.7 years

First QC Date

March 7, 2018

Last Update Submit

October 10, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Number of participants receiving the intervention

    We'll assess feasibility by determining the reach of the intervention

    24 months

  • Acceptability of the intervention

    We'll assess the acceptability of the CKD-PC intervention by qualitative interviews by reporting the percentage of patients with a favorable response to the intervention.

    24 months

Study Arms (2)

usual care

ACTIVE COMPARATOR
Other: usual care

CKD-EDU arm

EXPERIMENTAL
Behavioral: CKD-EDU

Interventions

CKD-EDUBEHAVIORAL

Palliative Care based coaching intervention for support with dialysis-related decision making.

CKD-EDU arm

Nephrologist based usual care

usual care

Eligibility Criteria

Age75 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Age ≥75 years old
  • Presence of advanced CKD stage 4 or 5 (i.e. e GFR ≤ 25 ml/min)
  • Patient's nephrologist is enrolled in the study and has seen that nephrologist at least once
  • Speaks English
  • Have not attended a dialysis education class or met with the dialysis education coordinator.
  • Have not made a dialysis decision

You may not qualify if:

  • Patient has already been seen by a palliative care clinician or is enrolled in hospice
  • Is already on dialysis
  • Hospitalized at the time of recruitment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Rochester Medical Center

Rochester, New York, 14642, United States

Location

Related Publications (1)

  • Saeed F, Horowitz RK, Allen RJ, Auinger P, Epstein RM, Fiscella KA, Veazie PJ, Duberstein PR. Feasibility and Acceptability of a Palliative Care Intervention among Older Adults with Advanced CKD and Their Caregivers. Kidney360. 2025 Feb 1;6(2):236-246. doi: 10.34067/KID.0000000622. Epub 2024 Oct 24.

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of medicine

Study Record Dates

First Submitted

March 7, 2018

First Posted

March 14, 2018

Study Start

May 31, 2018

Primary Completion

February 9, 2021

Study Completion

August 30, 2022

Last Updated

October 12, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations