NCT03434717

Brief Summary

This study aims to evaluate the effects of an intervention based on systematic screening of psychological distress as the basis for individualised support and rehabilitation following primary breast cancer surgery focusing on psychological , physical and health-economics outcomes. The aim is also to illuminate patients' and relatives' experiences and need of support during the rehabilitation .

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
643

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 15, 2018

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 15, 2018

Completed
9 months until next milestone

Study Start

First participant enrolled

November 15, 2018

Completed
7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

December 14, 2023

Status Verified

December 1, 2023

Enrollment Period

7 years

First QC Date

January 15, 2018

Last Update Submit

December 13, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Psychological Distress

    Psychological Distress measured by the "Distress thermometer". A instrument that the patients answer themselves measuring the level of distress and the potential problems the may have.

    Instrument will be answered approximately 1 week pre-operative and after surgery at 2 weeks, 3 ,6 ,9 and 1, 2 and 3 years postoperative. Evaluating change over time.

Secondary Outcomes (7)

  • General Quality of life

    Instrument will be answered approximately 1 week pre-operative and after surgery at 2 weeks, 3 ,6 ,9 and 1, 2 and 3 years postoperative. Evaluating change over time.

  • Information needs

    Instrument will be answered approximately 1 week pre-operative and after surgery at 2 weeks, 3 ,6 ,9 and 1, 2 and 3 years postoperative. Evaluating change over time.

  • Resilience

    Instrument will be answered approximately 1 week pre-operative and after surgery at 2 weeks, 3 ,6 ,9 and 1, 2 and 3 years postoperative. Evaluating change over time.

  • Life style changes

    Instrument will be answered approximately 1 week pre-operative and after surgery at 2 weeks, 3 ,6 ,9 and 1, 2 and 3 years postoperative. Evaluating change over time.

  • Health economics

    Evaluations will be conducted after data collection is finished. 6 months and one year after inclusion.

  • +2 more secondary outcomes

Study Arms (3)

Control (high distress)

EXPERIMENTAL

Control group receiving care as usual

Other: Care as usual

Individualised rehabilitation

EXPERIMENTAL

Patients with high distress receive the intervention "individualized rehabilitation" including evaluation of individual needs and based on that physical, psychological or social interventions to promote rehabilitation.

Other: Individualised rehabilitation

Control group (low distress)

EXPERIMENTAL

Control group receiving care as usual

Other: Care as usual

Interventions

Patients will get access/support to individualised rehabilitation based on their needs identified through the distress thermometer

Individualised rehabilitation

Patients will get care as usual

Control (high distress)Control group (low distress)

Eligibility Criteria

Age18 Years+
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Undergone treatment for primary breast cancer
  • ≤18 years old
  • Ability to communicate in Swedish
  • Written informed consent

You may not qualify if:

  • Recurrent disease
  • Palliative diagnosis
  • Pregnancy
  • Prior history of breast cancer
  • Inability to participate in the study due to cognitive impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Skåne university hospital

Malmo, Sweden

RECRUITING

Related Publications (3)

  • Olsson IM, Dykes C, Ryden L, Olsson-Moller U, Malmstrom M. Experiences of rehabilitation one year after breast cancer diagnosis-A focus group study from the ReScreen randomized controlled trial. PLoS One. 2025 Feb 13;20(2):e0315814. doi: 10.1371/journal.pone.0315814. eCollection 2025.

  • Malmstrom M, Holst-Hansson A, Olsson Moller U. The complexity of needs and roles of family members during breast cancer rehabilitation: a qualitative study. BMC Cancer. 2024 Nov 21;24(1):1430. doi: 10.1186/s12885-024-13200-x.

  • Olsson Moller U, Ryden L, Malmstrom M. Systematic screening as a tool for individualized rehabilitation following primary breast cancer treatment: study protocol for the ReScreen randomized controlled trial. BMC Cancer. 2020 May 29;20(1):484. doi: 10.1186/s12885-020-06815-3.

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Marlene Malmström, PhD

    Lund university, department of health siences, Lund

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Marlene Malmström, Ass professor

CONTACT

Ulrika Olsson Möller, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: RCT
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 15, 2018

First Posted

February 15, 2018

Study Start

November 15, 2018

Primary Completion

November 1, 2025

Study Completion

November 1, 2025

Last Updated

December 14, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations