Key Insights

Highlights

Success Rate

85% trial completion

Published Results

149 trials with published results (16%)

Research Maturity

484 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

9.0%

85 terminated out of 943 trials

Success Rate

85.1%

-1.4% vs benchmark

Late-Stage Pipeline

12%

117 trials in Phase 3/4

Results Transparency

31%

149 of 484 completed with results

Key Signals

149 with results85% success85 terminated

Data Visualizations

Phase Distribution

709Total
Not Applicable (251)
Early P 1 (10)
P 1 (123)
P 2 (208)
P 3 (85)
P 4 (32)

Trial Status

Completed484
Unknown143
Recruiting124
Terminated85
Active Not Recruiting57
Withdrawn24

Trial Success Rate

85.1%

Benchmark: 86.5%

Based on 484 completed trials

Clinical Trials (943)

Showing 20 of 20 trials
NCT07222215Phase 2Recruiting

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

NCT07644910Not ApplicableNot Yet RecruitingPrimary

Nudging Preventive Screening Via Message Framing and Bundling

NCT06966700Phase 3RecruitingPrimary

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

NCT04816006Not ApplicableRecruiting

Breast Cancer, Reasoning, and Activity Intervention

NCT05573893RecruitingPrimary

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

NCT04544189Phase 2Active Not RecruitingPrimary

Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant Versus Placebo Plus Fulvestrant in Chinese Men and Postmenopausal Women With Advanced Breast Cancer

NCT06926868Phase 2RecruitingPrimary

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT05113251Phase 3Active Not RecruitingPrimary

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

NCT07117214Phase 1RecruitingPrimary

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

NCT07598084Not Yet RecruitingPrimary

Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement

NCT06312176Phase 3RecruitingPrimary

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT01251900CompletedPrimary

BRCA Mutations in Latinas

NCT07060807Phase 3RecruitingPrimary

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

NCT05946668CompletedPrimary

Evaluation of Vaginal Microbiome as a Biomarker for the Improvement of Vaginal Health in Women With Breast Cancer, ARISE Study

NCT07213791Phase 1Recruiting

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

NCT05386108Phase 1RecruitingPrimary

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT02541435RecruitingPrimary

Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer

NCT07174336Phase 3RecruitingPrimary

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

NCT07114601Phase 1RecruitingPrimary

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT07038369Phase 1Active Not Recruiting

A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

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Research Network

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