NCT03429673

Brief Summary

The trial was designed to compare effectiveness and safety of surgeries in the patients with non-small cell lung cancer

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,885

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2017

Shorter than P25 for all trials

Geographic Reach
1 country

10 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2017

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 30, 2018

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 12, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2018

Completed
Last Updated

May 21, 2018

Status Verified

May 1, 2018

Enrollment Period

Same day

First QC Date

January 30, 2018

Last Update Submit

May 18, 2018

Conditions

Keywords

Chinesereal-world evidencesNSCLCsurgeries

Outcome Measures

Primary Outcomes (1)

  • Overall survival

    Overall survival

    2015-2017

Other Outcomes (4)

  • Overall survivals in the subgroups

    2015-2017

  • Impact factors of overall survival

    2015-2017

  • Death rate within 30/90 days after surgeries

    2015-2017

  • +1 more other outcomes

Study Arms (1)

Patients with surgeries

Pathologically diagnosed elderly early Chinese patients with non-small cell lung cancer who received lobectomy or segment/wedge dissection

Procedure: Surgeries

Interventions

SurgeriesPROCEDURE

Lobectomy or segment/wedge dissection

Patients with surgeries

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Pathological diagnosed elderly Chinese patients with non-small cell lung cancer who received lobectomy or segment/wedge dissection

You may qualify if:

  • Patients who received surgeries from 2014 to 2017;
  • Patients who received lobectomy or segment/wedge dissection;
  • Pathologically diagnosed patients with non-small cell lung cancer;
  • Patients with age \>=65 years old.

You may not qualify if:

  • Patients who received neoadjuvant therapy prior to surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

China-Japan Friendship Hospital

Beijing, Beijing Municipality, 100029, China

Location

China People's Liberation Army Hospital

Beijing, Beijing Municipality, 100853, China

Location

Henan Cancer Hospital

Zhengzhou, Henan, 450008, China

Location

Tongji Hospital Affiliated to Huaxi Technology University

Wuhan, Hubei, 430030, China

Location

Jiangsu Cancer Hospital

Nanjing, Jiangsu, 210009, China

Location

Xi'an Tangdu Hospital

Xi'an, Shaanxi, 710000, China

Location

Shanghai Chest Hospital

Shanghai, Shanghai Municipality, 200030, China

Location

Huaxi Hospital Affiliate to Sichuan University

Chengdu, Sichuan, 610041, China

Location

Tianjin Chest Hospital

Tianjin, Tianjin Municipality, 300051, China

Location

First Hospital Affiliated to Zhejiang University

Hangzhou, Zhejiang, 310003, China

Location

Related Publications (1)

  • Zhang Z, Feng H, Zhao H, Hu J, Liu L, Liu Y, Li X, Xu L, Li Y, Lu X, Fu X, Yang H, Liu D. Sublobar resection is associated with better perioperative outcomes in elderly patients with clinical stage I non-small cell lung cancer: a multicenter retrospective cohort study. J Thorac Dis. 2019 May;11(5):1838-1848. doi: 10.21037/jtd.2019.05.20.

MeSH Terms

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

Surgical Procedures, Operative

Condition Hierarchy (Ancestors)

Carcinoma, BronchogenicBronchial NeoplasmsLung NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 30, 2018

First Posted

February 12, 2018

Study Start

December 1, 2017

Primary Completion

December 1, 2017

Study Completion

March 30, 2018

Last Updated

May 21, 2018

Record last verified: 2018-05

Data Sharing

IPD Sharing
Will not share

Locations