Dietry Pattern and Lead Levels in Pregnancy
Dietary Patterns and Variability in Blood Lead Concentrations Among Pregnant British Women
1 other identifier
observational
2,167
0 countries
N/A
Brief Summary
During pregnancy lead crosses the placenta freely and can have adverse effects on the fetus, with the potential for life-long impact on the child. Identification of dietary patterns and food groups in pregnancy in relation to measures of lead status could provide a more useful alternative to a nutrient-specific advice to minimise fetal exposure to lead during pregnancy. The aim is to evaluate whether dietary patterns and food groups are associated with blood lead concentrations in pregnancy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 1991
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 1991
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 1992
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 1992
CompletedFirst Submitted
Initial submission to the registry
January 16, 2018
CompletedFirst Posted
Study publicly available on registry
January 23, 2018
CompletedJanuary 23, 2018
January 1, 2018
1.7 years
January 16, 2018
January 16, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Blood lead concentration
Blood lead concentration
During gestation
Study Arms (1)
Pregnant women
Pregnant women enrolled in ALSPAC
Interventions
Eligibility Criteria
The sample for this analysis was derived from the Avon Longitudinal Study of Parents and Children (ALSPAC), which is a UK-based birth cohort set up to investigate environmental and genetic influences on health and disease. ALSPAC recruited 14,541 pregnant women resident in Avon, UK with expected dates of delivery between 1st April 1991 and 31st December 1992.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Bristollead
- Wellcome Trustcollaborator
- Medical Research Councilcollaborator
- Bristol Biomedical Research Unitcollaborator
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Nic Timpson, PhD
University of Bristol
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 16, 2018
First Posted
January 23, 2018
Study Start
April 1, 1991
Primary Completion
December 1, 1992
Study Completion
December 1, 1992
Last Updated
January 23, 2018
Record last verified: 2018-01
Data Sharing
- IPD Sharing
- Will not share