NCT03325855

Brief Summary

A national data registry of patients receiving fecal microbiota transplantation (FMT) or other gut-related-microbiota products designed to prospectively assess short and long-term safety and effectiveness

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,000

participants targeted

Target at P75+ for all trials

Timeline
15mo left

Started Sep 2017

Longer than P75 for all trials

Geographic Reach
2 countries

53 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress87%
Sep 2017Aug 2027

Study Start

First participant enrolled

September 20, 2017

Completed
27 days until next milestone

First Submitted

Initial submission to the registry

October 17, 2017

Completed
13 days until next milestone

First Posted

Study publicly available on registry

October 30, 2017

Completed
9.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

January 21, 2026

Status Verified

January 1, 2026

Enrollment Period

9.9 years

First QC Date

October 17, 2017

Last Update Submit

January 18, 2026

Conditions

Keywords

FMTCDIFecal Matter Transplant

Outcome Measures

Primary Outcomes (2)

  • Occurrence of treatment related Adverse Events

    Adverse events to be monitored include surgeries, infection, hospitalization, other life-threatening events, death and newly diagnosed diseases.

    over 10 Years

  • Disease Re-occurrence Following FMT

    Assess effectiveness of FMT by monitoring disease re-occurrence post treatment.

    over 10 Years

Interventions

None - Observational

Also known as: Observational

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients receiving FMT or other gut-related-microbiota products and the donors providing specimens for the enrolled patients' FMT. Patients will be enrolled regardless of race, gender, ethnicity, or age.

You may qualify if:

  • Ability to give informed consent
  • Receiving FMT or other gut-related microbiota product within 90 days after providing consent
  • Access to internet and/or telephone
  • Ability to give informed consent
  • Providing stool sample for FMT

You may not qualify if:

  • Incarceration

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (53)

Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States

WITHDRAWN

Children's Hospital of Los Angeles

Los Angeles, California, 90027, United States

ACTIVE NOT RECRUITING

University of California

Los Angeles, California, 90095, United States

WITHDRAWN

Stanford University

Redwood City, California, 94063, United States

RECRUITING

Sutter Roseville Medical Center

Roseville, California, 95661, United States

RECRUITING

University of California San Francisco

San Francisco, California, 94115, United States

RECRUITING

Ventura Clinical Trials

Ventura, California, 93003, United States

WITHDRAWN

Yale New Haven Hospital

Hamden, Connecticut, 06518, United States

RECRUITING

MedStar Georgetown University Hospital

Georgetown, District of Columbia, 20007, United States

ACTIVE NOT RECRUITING

Best Quality Research, Inc.

Hialeah, Florida, 33016, United States

WITHDRAWN

University of Miami, Miller School of Medicine

Miami, Florida, 33136, United States

RECRUITING

GI Pros

Naples, Florida, 34102, United States

WITHDRAWN

Emory University School of Medicine

Atlanta, Georgia, 30307, United States

RECRUITING

The University of Chicago

Chicago, Illinois, 60637, United States

RECRUITING

University of Chicago School of Medicine

Chicago, Illinois, 60637, United States

ACTIVE NOT RECRUITING

NorthShore University Health System

Evanston, Illinois, 60201, United States

TERMINATED

Loyola University Medical Center

Maywood, Illinois, 60153, United States

ACTIVE NOT RECRUITING

Loyola University of Chicago/ Loyola University Medical Center

Maywood, Illinois, 60153, United States

RECRUITING

Carle Foundation Hospital

Urbana, Illinois, 61801, United States

COMPLETED

Indiana University School of Medicine

Indianapolis, Indiana, 46202, United States

RECRUITING

University of Kansas Medical Center Research Institute

Kansas City, Kansas, 66160, United States

RECRUITING

Ochsner

New Orleans, Louisiana, 70121, United States

RECRUITING

Johns Hopkins University School of Medicine

Baltimore, Maryland, 21287, United States

COMPLETED

American Gastroenterological Association

Bethesda, Maryland, 20814, United States

ACTIVE NOT RECRUITING

Boston Children's Hospital

Boston, Massachusetts, 02115, United States

RECRUITING

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

RECRUITING

UMass Memorial Health

Worcester, Massachusetts, 01604, United States

RECRUITING

St. Joseph Mercy Hospital

Ann Arbor, Michigan, 48105, United States

COMPLETED

University of Michigan

Ann Arbor, Michigan, 48109, United States

RECRUITING

Henry Ford Health Hospital

Detroit, Michigan, 48202, United States

RECRUITING

Mayo Clinic - Division of Pediatric Gastroenterology

Rochester, Minnesota, 55905, United States

RECRUITING

Mayo Clinic

Rochester, Minnesota, 55905, United States

RECRUITING

Valley Hospital and Medical Center

Las Vegas, Nevada, 89146, United States

ACTIVE NOT RECRUITING

Atlantic Health System

Morristown, New Jersey, 07960, United States

COMPLETED

Rutgers

New Brunswick, New Jersey, 08901, United States

RECRUITING

Penn Medicine Princeton Health

Plainsboro, New Jersey, 08536, United States

NOT YET RECRUITING

Concorde Medical Group

New York, New York, 10016, United States

WITHDRAWN

New York University School of Medicine

New York, New York, 10016, United States

RECRUITING

Weill Cornell Medicine - Pediatric

New York, New York, 10021, United States

WITHDRAWN

Weill Cornell Medicine

New York, New York, 10021, United States

RECRUITING

Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States

RECRUITING

Gastroenterology Group of Rochester, LLP

Rochester, New York, 14618, United States

COMPLETED

University of North Carolina

Chapel Hill, North Carolina, 27599, United States

RECRUITING

Oregon Health & Science University

Portland, Oregon, 97239, United States

RECRUITING

Temple University

Philadelphia, Pennsylvania, 19140, United States

ACTIVE NOT RECRUITING

Brown University Women's Medicine and Collaborative

Providence, Rhode Island, 02904, United States

ACTIVE NOT RECRUITING

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

ACTIVE NOT RECRUITING

Texas Children's Hospital / Baylor College of Medicine

Houston, Texas, 77030, United States

WITHDRAWN

Baylor Research Institute - Scott & White Medical Center

Temple, Texas, 76508, United States

COMPLETED

West Virginia University

Morgantown, West Virginia, 26506, United States

NOT YET RECRUITING

University of Wisconsin - Madison

Madison, Wisconsin, 53705, United States

RECRUITING

The Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

RECRUITING

University of Alberta

Edmonton, Alberta, T6G2X8, Canada

WITHDRAWN

MeSH Terms

Conditions

Clostridium Infections

Interventions

Watchful Waiting

Condition Hierarchy (Ancestors)

Gram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfections

Intervention Hierarchy (Ancestors)

Outcome Assessment, Health CareOutcome and Process Assessment, Health CareQuality of Health CareHealth Services Administration

Study Officials

  • Gary D Wu, MD

    Co-Director, PennCHOP Microbiome Program

    PRINCIPAL INVESTIGATOR
  • Colleen Kelly, MD

    Brigham and Women's Hospital

    PRINCIPAL INVESTIGATOR
  • Loren Laine, MD

    Yale University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sonya Serra, MSc

CONTACT

Lydia Fredell, MA

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
10 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 17, 2017

First Posted

October 30, 2017

Study Start

September 20, 2017

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

January 21, 2026

Record last verified: 2026-01

Locations