NCT03392350

Brief Summary

We evaluated the effectiveness of a combination of a comprehensive health assessment consisting of the combination of a screening full body scan employing graphic patient education and motivational techniques followed by intensive, individualized behavioral training and management program on improved adherence to beneficial lifestyle behaviors, as well as possibly reduced risk of disease.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
267

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2012

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 15, 2012

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 20, 2015

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

December 29, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 5, 2018

Completed
Last Updated

January 5, 2018

Status Verified

December 1, 2017

Enrollment Period

3.3 years

First QC Date

December 29, 2017

Last Update Submit

December 29, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Progression of Coronary Artery Calcium

    Coronary artery calcium (CAC) was assessed by a trained technologist with the Agatston score measured and volume score calculated, summed among the four major coronary arteries using conventional methods.

    2 years

Secondary Outcomes (1)

  • Epicardial and Thoracic fat volume (in cm3)

    2 years

Study Arms (2)

Behavioral Intervention arm

ACTIVE COMPARATOR

A behavioral intervention consisting of a physician body scan consultation with a radiologist which included viewing self imagery followed by an 18 month behavioral intervention which included educational modules covering: Responding to Stress More Effectively Enhancing the effects of Relaxation Nourishing your immune system Energizing your Body Welcoming Others and Strengthening Relationships

Behavioral: Physician Body Scan Consultation with Behavioral Intervention

Control Group

ACTIVE COMPARATOR

No Intervention

Behavioral: Physician Body Scan Consultation with Behavioral Intervention

Interventions

The RENEW™ program consisted of 7 bi-monthly face-to-face web sessions over 16-18 weeks followed by an average of 15 monthly check-in sessions (maintenance) over 80 weeks.This included modules on responding to stress, enhancing effects of relaxation, nourishing theimmune system, physical activity, and social support.

Behavioral Intervention armControl Group

Eligibility Criteria

Age35 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men or women aged 35 and over who provide informed consent to participate including the baseline, interim, and follow-up clinic visits, as well as willingness to participate in the on-line intervention (if selected to be in that group) -

You may not qualify if:

  • Known cardiovascular disease, cancer, or any life-threatening or debilitating illness, including psychiatric illnesses, or significant difficulty with the English language that would preclude successful participation in the program

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Coronary DiseaseBehaviorHypertensionHypercholesterolemia

Interventions

Behavior Therapy

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesHyperlipidemiasDyslipidemiasLipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

PsychotherapyBehavioral Disciplines and Activities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Masking Details
The staff doing the end point assessment were blinded as to treatment assignment.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: One Control group one Intervention arm. The intervention group are the only subjects receiving a body scan consultation and behavioral intervention.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 29, 2017

First Posted

January 5, 2018

Study Start

June 15, 2012

Primary Completion

September 15, 2015

Study Completion

November 20, 2015

Last Updated

January 5, 2018

Record last verified: 2017-12

Data Sharing

IPD Sharing
Will not share