Patients on Antithrombotics for Colonoscopy
Prospective Collection of Clinical and Laboratory Variables of Patients Receiving Antithrombotics and Requiring Colonoscopy
1 other identifier
observational
6,000
1 country
1
Brief Summary
The use of antithrombotics (antiplatelet agents and anticoagulants) is increasing with an aging global population.Management of antithrombotics in patients undergoing invasive procedures including gastrointestinal endoscopy remains a challenge. Management approach includes taking a precarious balance between the risk of thromboembolism after interruption of antithrombotics and risk of bleeding with the continuation of antithrombotics. Colonoscopy remains one of the commonest endoscopic procedures performed. The optimal management strategy of different antithrombotics during colonoscopy remains unclear.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2017
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 30, 2017
CompletedFirst Posted
Study publicly available on registry
December 6, 2017
CompletedStudy Start
First participant enrolled
December 8, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 30, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 30, 2028
January 18, 2022
January 1, 2022
10 years
November 30, 2017
January 14, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Delayed post polypectomy bleeding
Delayed post polypectomy bleeding is defined as blood per rectum occurring after colonoscope has been retracted from the anus to 30 days after the procedure requiring hospitalization or treatment.
Within 30 days
Secondary Outcomes (2)
Immediate post polypectomy bleeding
During Colonoscopy
Serious cardiovascular event
Within 6 months.
Study Arms (1)
Antithrombotics
The patients should be on antithrombotics on the day of colonoscopy arrangement
Eligibility Criteria
Patients receiving antithrombotics at colonoscopy arrangement and undergoing elective colonoscopy
You may qualify if:
- Patients must be over 18 years of age
- Patients undergoing elective colonoscopy for any indication, who are receiving antithrombotics
- Informed consent is obtained
You may not qualify if:
- Patients under 18 years of age
- Inability to give informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Chinese University of Hong Konglead
- Beijing Friendship Hospitalcollaborator
Study Sites (1)
Prince of Wales Hospital
Hong Kong, Hong Kong
Related Publications (1)
Jiang W, Suen BY, Ho HT, Ching JYL, Chan FKL, Mak JWY. Impact of Physicians' and Patients' Compliance on Outcomes of Colonoscopic Polypectomy With Anti-Thrombotic Therapy. Clin Gastroenterol Hepatol. 2021 Dec;19(12):2559-2566.e1. doi: 10.1016/j.cgh.2020.09.019. Epub 2020 Sep 12.
PMID: 32931958DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Moe Htet Kyaw, MBBS
Chinese University of Hong Kong
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate professor
Study Record Dates
First Submitted
November 30, 2017
First Posted
December 6, 2017
Study Start
December 8, 2017
Primary Completion (Estimated)
November 30, 2027
Study Completion (Estimated)
November 30, 2028
Last Updated
January 18, 2022
Record last verified: 2022-01