WhatsApp Reminder on Bowel Preparation Level
Can a WhatsApp Reminder Improve the Quality of Screening Colonoscopy? A Randomized Controlled Study
1 other identifier
interventional
666
1 country
1
Brief Summary
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries. In Hong Kong, colorectal cancer ranks first in cancer incidence and second in cancer mortality based on data from 2014. CRC is one of the most preventable cancers because its development in general follows an adenoma-carcinoma sequence. Adenomas are considered precursor lesions for CRC. Recent guidelines from USA, Europe and Asia Pacific region recommend CRC screening for average-risk asymptomatic individuals starting at age 50. Modalities such as guaiac-based fecal occult blood tests (gFOBT), fecal immunochemical tests (FIT), flexible sigmoidoscopy (FS), and colonoscopy are among the acceptable options for CRC screening. While early detection and removal of colorectal adenoma by screening colonoscopy with polypectomy reduce CRC incidence and mortality, interval cancers (cancers that develop after a colonoscopy and before the next scheduled colonoscopy) may still occur and were reported to account for up to 10.5% of CRC. a CRC has been associated with proximal colon location, small lesion, flat lesion, missed lesion, inadequate examination, incomplete resection of lesion, tumor biology, and low adenoma detection rate (ADR). High ADR (eg, ≥ 20%) has been associated with a reduced risk of interval CRC. Bowel preparation includes diet restriction and proper use of laxative before the colonoscopy, and this is one of the important factors to ensure a high quality colonoscopy. Suboptimal bowel preparation may lead to decreased ADR, cecal intubation rate, and surveillance interval and increased procedural time. Efforts to improve bowel cleansing quality through traditional communication routines, including face-to-face verbal education, written booklet or visual aids or telephone-based re-instruction have proven to be useful. A recent study using WeChat, a widely used social media mobile app in China, has also shown to be effectively improving bowel preparation level of a mixed population who received diagnostic (77%), screening (15.8%) and surveillance (7.2%) colonoscopy. However, the impact of social media mobile app on the bowel preparation level of screening colonoscopy is not yet known. Hence, this study will investigate the effectiveness of the most popular social media app worldwide, WhatsApp in bowel preparation level of screening colonoscopy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 2, 2017
CompletedFirst Submitted
Initial submission to the registry
July 4, 2017
CompletedFirst Posted
Study publicly available on registry
July 6, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 17, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2019
CompletedJune 14, 2021
June 1, 2021
1.9 years
July 4, 2017
June 11, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Bowel preparation level
Proportion of subjects having optimal bowel preparation level
Immediate after colonoscopy
Secondary Outcomes (3)
Polyp detection rate
Immediate after colonoscopy
adenoma detection rate
a month after colonoscopy
Mean number of adenoma detected per patient
1 year after study started, i.e. when all subjects undergo colonoscopy
Study Arms (2)
WhatsApp reminder
ACTIVE COMPARATORAn additional WhatsApp reminder with same content of the written instruction and a video of explanation of bowel preparation by a nurse 4 days prior colonoscopy
No reminder
NO INTERVENTIONNo additional reminder will be given
Interventions
An additional WhatsApp reminder with same content of the written instruction and a video of explanation of bowel preparation by a nurse 4 days prior colonoscopy
Eligibility Criteria
You may qualify if:
- Subjects arranged for an out-patient screening colonoscopy in Prince of Wales Hospital and Alice Ho Miu Ling Hospital.
You may not qualify if:
- Lack of access to WhatsApp Messenger
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Prince of Wales Hospital
Hong Kong, Hong Kong
Related Publications (1)
Lam TYT, Wu PI, Tang RSY, Tse YK, Lau JYW, Wu JCY, Sung JJY. Nurse-led reinforced education by mobile messenger improves the quality of bowel preparation of colonoscopy in a population-based colorectal cancer screening program: A randomized controlled trial. Int J Nurs Stud. 2022 Sep;133:104301. doi: 10.1016/j.ijnurstu.2022.104301. Epub 2022 May 30.
PMID: 35764027DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Thomas Yuen Tung Lam, MSc
Chinese University of Hong Kong
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Masking Details
- Endoscopists will be masked if the patients have received WhatsApp reminder prior colonoscopy
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Nursing Officer
Study Record Dates
First Submitted
July 4, 2017
First Posted
July 6, 2017
Study Start
June 2, 2017
Primary Completion
April 17, 2019
Study Completion
December 31, 2019
Last Updated
June 14, 2021
Record last verified: 2021-06