Emergency Medical Services and Epilepsy in Switzerland

NCT03346382 | Completed

• 1 other identifier: OMT 01012015 SRZ
• Study Type: observational
• Target: 584
• Locations: 0 countries
• Sites: N/A

Brief Summary

Retrospective data analysis, all emergency medical services of the city of Zurich interventions due to epileptic convulsions during June 2013 and December 2014 have been analyzed regarding the type of drug used, its application mode and the application mode based success. Furthermore, children versus adults were compared. Continuous variables were summarized as mean ± standard deviation (SD) and also presented as median \[minimum; maximum\]. Groups were compared using the independent samples t-test. P-values \< 0.05 are considered significant.

Conditions

Epilepsy

Keywords

Epilepsy; Emergency medical services

Outcome Measures

Primary Outcomes (1)

• Which drug (Midazolam versus Diazepam) better stops epileptic seizures in the pre-clinical setting

  In this retrospective trial, all Emergency Medical Services of the city of Zurich interventions due to epileptic seizures during June 2013 and December 2014 are analyzed regarding the two drugs (Midazolam or Diazepam) used, its application mode (intravenous, nasal, intramuscular, rectal) and the application mode based success. Data will be collected regarding these aspects in order to determine if one drug is better than the other one, and which application mode is the most efficient. Furthermore, children versus adults are compared. Continuous variables are summarized as mean ± standard deviation (SD) and also presented as median \[minimum; maximum\]. Groups are compared using the independent samples t-test. P-values \< 0.05 are considered significant.

  follow up up to 1 year

Secondary Outcomes (1)

• Does the way of application of the drugs (Midazolam versus Diazepam) used in pre-clinical epileptic seizures influence the outcome

  follow up up to 1 year

Eligibility Criteria

• Age: Up to 99 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

retrospective collected data from the emergency medical system "Schutz \& Rettung Zürich", Zurich, Switzerland, over an 18 months period from 01. June 2013 till 31. December 2014 - all calls for epileptic seizures

You may qualify if:

• emergency calls for epileptic seizures received by the emergency medical system of Zurich,Switzerland,
• the use of midazolam or diazepam or no drug used.

You may not qualify if:

• the use of any other first line drug to stop seizures than the two mentioned above e.g. thiopental

Sponsors & Collaborators

• Theusinger Oliver M.: lead

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Oliver M Theusinger, MD

  Balgrist University Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 2, 2017
• First Posted: November 17, 2017
• Study Start: March 1, 2015
• Primary Completion: December 31, 2015
• Study Completion: June 30, 2016
• Last Updated: November 17, 2017

Record last verified: 2017-11

Data Sharing

• IPD Sharing: Will not share