NCT02547389

Brief Summary

Improving medical compliance and health-related quality of life (HRQoL) among people with epilepsy (PWE) has become the focus of various treatment programs and behavioral interventions which continue to be challenging to both patients and health care professionals. In order to design an effective intervention on the management of epilepsy, the drug management of epilepsy by community health workers was evaluated.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
144

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2014

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2015

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 11, 2015

Completed
Last Updated

September 11, 2015

Status Verified

September 1, 2015

Enrollment Period

1.2 years

First QC Date

September 2, 2015

Last Update Submit

September 9, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Compliance with taking prescribed medications

    Assessment of compliance with taking medications at regularly scheduled intervals

    12 months

Secondary Outcomes (2)

  • Seizure frequency per month

    change from baseline to 12 months in number of seizures per month assessed by patients diary

  • Quality of Life (Malay Quality of Life in Epilepsy Inventory-30)

    change from baseline to 12 months in quality of life assessed by Malay Quality of Life in Epilepsy Inventory-30

Study Arms (2)

Intervention Group (IG)

ACTIVE COMPARATOR

IG additionally received community health programs with health workers(intensive education, consultation services, maintenance of anepilepsy tracking card, and repeated reminders).

Behavioral: Community support group

Control Group (CG)

OTHER

Patients in the CG were supplied with only printed epilepsy educational module

Other: Printed material Supported

Interventions

Intervention Group (IG)
Control Group (CG)

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients must have a seizure frequency of at least two seizures in a 6 month period of time.
  • Patients must be on at least one anti-epileptic medication.
  • Patients must be able to report seizure frequency with either a paper or electronic diary.
  • Patients must be able to read and understand either English or Hindi.
  • Patients must be able to complete questionnaires and provide informed consent to this study.

You may not qualify if:

  • A diagnosis of psychogenic nonepileptic seizures
  • Severe depression, anxiety, or psychosis
  • Recent problem with substance abuse.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Hitesh K Nayak

    NMP Medical Research Institute

    PRINCIPAL INVESTIGATOR
  • Neha Sharma, PhD

    Macmillan Research Group UK

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 2, 2015

First Posted

September 11, 2015

Study Start

January 1, 2014

Primary Completion

April 1, 2015

Study Completion

June 1, 2015

Last Updated

September 11, 2015

Record last verified: 2015-09