Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children

NCT03273725 | Completed

• 1 other identifier: TannhelsetjenestensKM
• Study Type: observational
• Target: 178
• Locations: 0 countries
• Sites: N/A

Brief Summary

The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.

Conditions

Vitamin D Deficiency; Dental Caries; Dental Enamel Hypoplasia

Keywords

Oral Health; Vitamin D

Outcome Measures

Primary Outcomes (1)

• Dental caries in the primary teeth of the children at the age of 7-9 yrs

  The main study was conducted in 2007 - 2009. In the current study the children of the mothers participating in the main study are invited to the follow-up study "Trip Tooth Study" with data collection (dental examination) taking place over a time span of two years.

  2016 - 2017

Secondary Outcomes (2)

• Enamel defects in the primary teeth of the children at the age of 7-9 yrs

  2016 - 2017

• Antimicrobial peptides in saliva

  2016 - 2017

Interventions

Dental examination including taking a saliva sample. OTHER

The main focus of the dental examination is enamel defects and caries. Saliva samples (stimulated) will also be taken.

Eligibility Criteria

• Age: 7 Years - 9 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

All n=855 mother/child pairs who participated in the initial TRIP study in 2007-2009 will be invited to participate in the follow-up study in 2016-2017.

You may qualify if:

• Mother of the child participated in the main study "Training in Pregnancy"

You may not qualify if:

• Consent not given

Sponsors & Collaborators

• Tannhelsetjenestens Kompetansesenter Midt-Norge: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

Saliva samples

MeSH Terms

Conditions

Vitamin D Deficiency; Dental Caries; Dental Enamel Hypoplasia

Condition Hierarchy (Ancestors)

Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases; Developmental Defects of Enamel; Tooth Abnormalities; Stomatognathic System Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Research

Study Record Dates

• First Submitted: January 24, 2016
• First Posted: September 6, 2017
• Study Start: June 1, 2016
• Primary Completion: August 1, 2017
• Study Completion: August 1, 2017
• Last Updated: September 6, 2017

Record last verified: 2017-09

Data Sharing

• IPD Sharing: Will not share