NCT02368028|Completed
Loading search results
Sponsor study identifier
Secondary identifiers
NIH
observational
131
1 country
1
Study Start
March 2015
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2015
Actual (reported)Study Completion
September 2015
Actual (reported)The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management. Dental caries occurs when acids produced by bacterial glycolysis of dietary carbohydrates causes demineralization of the tooth enamel. A major focus of caries research has been on identifying and characterizing acid-generating bacteria and the mechanisms of acid resistance. The purpose of this study is to investigate the type of bacteria that grows in the mouth and on teeth.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2015
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 13, 2015
Actual (reported)February 20, 2015
Actual (reported)March 2015
Date type not reportedThis date has not been verified as actual or estimated.
September 2015
Actual (reported)September 2015
Actual (reported)Arginolytic activity in oral samples
Oral samples, saliva and dental plaque, will be collected and their arginolytic activity wil be compared between the two groups.
Day 1
Type of oral bacteria
Day 1
Oral health
Day 1
Participants who do not have caries (cavities) will have oral samples collected.
Participants who do have caries (cavities) will have oral samples collected.
Oral samples of saliva, dental plaque and DNA will be collected between the two groups.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
The study population will consist of unrelated children aged between 2 and 5 years with different levels of caries experience.
Dental Clinical Research Unit, University of Florida
Gainesville, Florida, 32610, United States
Nascimento MM, Liu Y, Kalra R, Perry S, Adewumi A, Xu X, Primosch RE, Burne RA. Oral arginine metabolism may decrease the risk for dental caries in children. J Dent Res. 2013 Jul;92(7):604-8. doi: 10.1177/0022034513487907. Epub 2013 May 2.
Saliva and Dental Plaque
Marcelle Nascimento, DDS, PhD
University of Florida
131 participants (actual enrollment reported by the registry).
First Submitted
February 13, 2015
First Posted
February 20, 2015
Study Start
March 2015
Date type not reportedThis date has not been verified as actual or estimated.
Evaluation of Oral Hygiene Products in an In Situ Caries Model
Contact the study team to confirm eligibility.
Primary Completion
September 2015
Actual (reported)Study Completion
September 2015
Actual (reported)Last Updated
September 15, 2015
Record last verified: 2015-09
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: