NCT03264937|CompletedDMC
Social-software iMproving wARfarin Therapy
SMART
Randomized Evaluation of Social-software Improving Warfarin Therapy in Patients With Mechanical Heart Valve Replacement
Loading search results
SMART
Randomized Evaluation of Social-software Improving Warfarin Therapy in Patients With Mechanical Heart Valve Replacement
Sponsor study identifier
interventional
735
1 country
1
Study Start
September 1, 2017
Actual (reported)Primary Completion
March 1, 2019
Actual (reported)Study Completion
March 8, 2019
Actual (reported)Poor anticoagulation quality is a major problem among Chinese patients receiving warfarin therapy in traditional health care settings. Improving warfarin therapy has been crucial for Chinese patients. Wechat is social-software in China. Most of all Chinese adults use Wechat, as well as our patients. So we set up a Wechat-based mini-program to instruct Chinese patients' warfarin therapy. We aim to assess whether social software could improve warfarin therapy in Chinese patients by conducting a single-centre, open-label, prospective, randomized clinical trial.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 8, 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 22, 2017
Actual (reported)August 29, 2017
Actual (reported)September 1, 2017
Actual (reported)March 1, 2019
Actual (reported)March 8, 2019
Actual (reported)Time to First Event
Thrombotic events, such as Valve thrombosis, Stroke, Peripheral embolism; Major bleeding, such as cerebral hemorrhage，gastrointestinal bleeding etc.
Up to 18 months
Time in therapeutic range
Up to 18 months
Individual variation of International Normalized Ratio (INR)
Up to 18 months
Times of extremely high International Normalized Ratio (INR) values
Up to 18 months
We set up a mini-program based on wechat application. We instruct warfarin therapy via social-software including dose adjustment, answer questions, remind monitoring INR et.al.
This is the control group, Warfarin therapy was managed via traditional style without social software intervention.
Using Wechat application, a social platform, to manage warfarin therapy in patients with mechanical valve replacement.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
WAHH
Wuhan, Hubei, 430000, China
Zhang L, Li S, Li Z, Yu D, Wu H, Hua B, Xie L, Yuan X, Li Y, Zhang Z, Long Y. Social App to Improve Warfarin Therapy in Post-MHVR Chinese Patients: A Randomized Controlled Trial. Cardiovasc Ther. 2023 Jan 14;2023:2342111. doi: 10.1155/2023/2342111. eCollection 2023.
Zhenlu Zhang, MD,PhD
Wuhan Asia Heart Hospital
735 participants (actual enrollment reported by the registry).
First Submitted
August 22, 2017
First Posted
August 29, 2017
Study Start
September 1, 2017
Actual (reported)Effect of Levocarnitine Supplementation for the Management of Fatigue in Levothyroxine-Treated Hypothyroid Patients
Contact the study team to confirm eligibility.
Primary Completion
March 1, 2019
Actual (reported)Study Completion
March 8, 2019
Actual (reported)Last Updated
June 19, 2019
Record last verified: 2019-06
We are going to make individual participant data (IPD) available to other researchers after our paper published
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: