NCT04052750

Brief Summary

The effect of SMS follow-up on drug compliance and efficacy in patients with FGIDs has not been reported in the literature. We, therefore, conducted a prospective randomized controlled trial to investigate whether SMS follow-up could improve treatment adherence in patients with FGIDs, which in turn would help symptom relief and improve treatment outcomes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
176

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 30, 2019

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

August 3, 2019

Completed
9 days until next milestone

First Posted

Study publicly available on registry

August 12, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2020

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2021

Completed
Last Updated

August 12, 2019

Status Verified

August 1, 2019

Enrollment Period

1 year

First QC Date

August 3, 2019

Last Update Submit

August 9, 2019

Conditions

Keywords

Functional Gastrointestinal Disorders, Adherence

Outcome Measures

Primary Outcomes (1)

  • Treatment compliance in outpatients with FGIDs

    Compliance is assessed by the medication possession ratio (MPR). The MPR is often defined as the sum of the days' supply of medication divided by the number of days between the first fill and the last refill plus the days' supply of the last refill. This calculation usually results in a ratio less than 1.0 if there are lapses in prescription refilling.

    week2

Secondary Outcomes (1)

  • Improvement of abdominal pain in outpatients with FGIDs

    week2

Study Arms (2)

The control group

NO INTERVENTION

Patients in this group only received medications without daily text message reminder

The intervention group

EXPERIMENTAL

Patients in this group received a daily short message service (SMS) reminder when medications were prescribed

Behavioral: SMS follow-up

Interventions

SMS follow-upBEHAVIORAL

In addition to conventional treatment, the experimental group received SMS reminding every day until the end of the treatment.

The intervention group

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with newly diagnosed FGIDs according to Rome-IV
  • Aged 18-70 years
  • With no obvious organic abnormalities

You may not qualify if:

  • With organic gastrointestinal diseases
  • With psychiatric diseases or are taking psychotropic agents
  • With severe cardiopulmonary or other organ diseases
  • Pregnant women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

RenJiH

Shanghai, China

RECRUITING

Related Publications (1)

  • Wang B, Luo QQ, Li Q, Cheng L, Chen SL. Daily Short Message Service Reminders Increase Treatment Compliance and Efficacy in Outpatients with Functional Dyspepsia: a Prospective Randomized Controlled Trial. J Gen Intern Med. 2020 Oct;35(10):2925-2931. doi: 10.1007/s11606-020-06088-3. Epub 2020 Aug 10.

MeSH Terms

Conditions

Gastrointestinal DiseasesPatient Compliance

Condition Hierarchy (Ancestors)

Digestive System DiseasesPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor,chief physician

Study Record Dates

First Submitted

August 3, 2019

First Posted

August 12, 2019

Study Start

April 30, 2019

Primary Completion

April 30, 2020

Study Completion

April 30, 2021

Last Updated

August 12, 2019

Record last verified: 2019-08

Locations