NCT03203109

Brief Summary

Retrospective cohort study of consecutive patients investigated in a neurorehabilitation ward after a first hemispheric stroke. Postural and gait disorders in relation to referential of verticality have been analyzed in routine care.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2012

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
5.3 years until next milestone

First Submitted

Initial submission to the registry

May 2, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 29, 2017

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2019

Completed
Last Updated

November 8, 2019

Status Verified

November 1, 2019

Enrollment Period

7.8 years

First QC Date

May 2, 2017

Last Update Submit

November 7, 2019

Conditions

Stroke

Keywords

lateropulsionpusher syndromeposturebalancePASSverticality perceptiongait

Outcome Measures

Primary Outcomes (1)

  • Posture

    Change from Baseline Score of Postural Assessment Scale for Stroke (PASS) at discharge

    admission and monthly, up to 3 months

Secondary Outcomes (23)

  • Balance

    admission and monthly, up to 3 months

  • Gait

    admission and monthly, up to 3 months

  • Postural disorders

    admission and monthly, up to 3 months

  • Visual vertical perception

    admission and monthly, up to 3 months

  • Postural vertical perception

    admission and monthly, up to 3 months

  • +18 more secondary outcomes

Interventions

Postural Assessment Scale for Stroke (PASS)BEHAVIORAL

Postural Assessment Scale for Stroke (PASS)

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

consecutive patients admitted in neurorehabilitation ward after first hemispheric stroke

You may not qualify if:

  • history of neurological disorders interfering with balance history of vestibularly disorders interfering with balance unstable medical conditions history of cognitive disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (6)

  • Lafitte R, Diaine F, Dai S, Carre O, Dupierrix E, Jolly C, Piscicelli C, Perennou D. Writing and drawing tilts after right hemisphere stroke are signs of a wrong verticality representation. Ann Phys Rehabil Med. 2025 May;68(4):101923. doi: 10.1016/j.rehab.2024.101923. Epub 2025 Jan 15.

    PMID: 39818122DERIVED

  • Dai S, Piscicelli C, Marquer A, Lafitte R, Clarac E, Detante O, Perennou D. Improving orientation with respect to gravity enhances balance and gait recovery after stroke: DOBRAS cohort. Ann Phys Rehabil Med. 2024 Feb;67(1):101767. doi: 10.1016/j.rehab.2023.101767. Epub 2024 Jan 23.

    PMID: 38266575DERIVED

  • Perennou D, Chauvin A, Piscicelli C; Collaborators for the posturography study in the Determinants of Balance Recovery After Stroke (DOBRAS) cohort; Hugues A, Dai S. Determining an optimal posturography dataset to identify standing behaviors in the post-stroke subacute phase. Cross-sectional study. Ann Phys Rehabil Med. 2023 May;66(4):101707. doi: 10.1016/j.rehab.2022.101707. Epub 2023 Jan 4.

    PMID: 36182062DERIVED

  • Dai S, Piscicelli C, Clarac E, Baciu M, Hommel M, Perennou D. Lateropulsion After Hemispheric Stroke: A Form of Spatial Neglect Involving Graviception. Neurology. 2021 Apr 27;96(17):e2160-e2171. doi: 10.1212/WNL.0000000000011826. Epub 2021 Mar 15.

    PMID: 33722996DERIVED

  • Dai S, Piscicelli C, Lemaire C, Christiaens A, Schotten MT, Hommel M, Krainik A, Detante O, Perennou D. Recovery of balance and gait after stroke is deteriorated by confluent white matter hyperintensities: Cohort study. Ann Phys Rehabil Med. 2022 Jan;65(1):101488. doi: 10.1016/j.rehab.2021.101488. Epub 2021 Nov 11.

    PMID: 33450367DERIVED

  • Dai S, Piscicelli C, Clarac E, Baciu M, Hommel M, Perennou D. Balance, Lateropulsion, and Gait Disorders in Subacute Stroke. Neurology. 2021 Apr 27;96(17):e2147-e2159. doi: 10.1212/WNL.0000000000011152. Epub 2020 Nov 11.

    PMID: 33177223DERIVED

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Dominic Pérennou, MD PhD

    University Hospital, Grenoble

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 2, 2017

First Posted

June 29, 2017

Study Start

January 1, 2012

Primary Completion

October 31, 2019

Study Completion

October 31, 2019

Last Updated

November 8, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing
Will not share