NCT03058770

Brief Summary

A prospective, randomized double-blind clinical trial will be conducted to determine the effect of a sensorimotor retraining program on the sensory and functional recovery of the paretic lower limb of subjects with chronic sequelae from stroke.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Feb 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 16, 2017

Completed
Same day until next milestone

Study Start

First participant enrolled

February 16, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 23, 2017

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2018

Completed
Last Updated

May 16, 2024

Status Verified

May 1, 2024

Enrollment Period

1.1 years

First QC Date

February 16, 2017

Last Update Submit

May 13, 2024

Conditions

Keywords

chronic stroke, sensorimotor retraining

Outcome Measures

Primary Outcomes (1)

  • Light touch

    Von Frey monofilaments

    6 weeks

Secondary Outcomes (3)

  • Static balance

    6 weeks

  • Plantar pressure distribution

    6 weeks

  • Gait

    6 week

Study Arms (2)

sensorimotor retraining program

EXPERIMENTAL

Fifteen 40-minute sensorimotor retraining sessions will be provided over a 5-week period.

Other: Sensorimotor retraining

Relaxation technique

ACTIVE COMPARATOR

Subjects will perform fifteen 40-minute relaxation sessions over a 5-week period.

Other: Relaxation technique

Interventions

Subjects will receive education regarding sensation and sensory retraining; practice in detection and localization of touch and in discrimination of hardness, texture and temperature in sitting and standing with vision obscured; proprioception training; and practice of these sensations in functional activities.

sensorimotor retraining program

Subjects will perform guided relaxation by using the Jacobson technique.

Relaxation technique

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chronic hemiplegia or hemiparesis from a first ever stroke (onset \> 6 months prior to study enrolment)
  • No severe cognitive deficit (Mini-Mental State Examination score ≥ 22)
  • Subjective reports of sensory loss
  • Triceps surae muscles scoring ≤ 2 on the Modified Ashworth Scale
  • Able to walk for at least 10 meters indoor over ground without assistance

You may not qualify if:

  • Ataxia
  • Co-existing sensory deficits from peripheral neuropathies (i.e. diabetes mellitus)
  • Lower extremity claudication
  • Pain \> 3/10 on a visual analogue scale
  • Prior lower extremity surgical history
  • Blindness, visual impairments and other pathologic condition that influence posture and balance.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Valencia

Valencia, 46010, Spain

Location

MeSH Terms

Conditions

Stroke

Interventions

Relaxation Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • M. Arántzazu Ruescas-Nicolau, PhD

    University of Valencia

    PRINCIPAL INVESTIGATOR
  • M.Luz Sanchez-Sanchez

    University of Valencia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

February 16, 2017

First Posted

February 23, 2017

Study Start

February 16, 2017

Primary Completion

March 31, 2018

Study Completion

March 31, 2018

Last Updated

May 16, 2024

Record last verified: 2024-05

Locations