Active Video Games for Older Adults With Knee and/or Hip Osteoarthritis.

NCT05839262 | Completed DMC

• 1 other identifier: UNAB-FCR-KINE2023B
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Population aging is currently an issue of primary relevance, constituting an enormous challenge for institutions and society. On the other hand, osteoarthritis (OA) is the most prevalent arthropathy in the elderly, strongly related to loss of functional capacity, limitation of daily activities, increased musculoskeletal pain, and deterioration of quality of life. More specifically, knee and hip OA represent a significant burden for health systems, and in Chile, they are among the ten most frequent diseases in the elderly. The technological development of the last decades has allowed the incorporation of several therapeutic alternatives for the intervention of the elderly, such as virtual reality, which allows interaction with multiple digital environments. Active video games (AVG) or exergames, carried out through commercial non-immersive virtual reality systems, have been proposed as a feasible, innovative, and entertaining alternative to optimize conventional physical rehabilitation (CPR). AVG in healthy older people and those with neurocognitive conditions effectively improves clinical and psychosocial outcomes. However, it has been recommended to advance the study of the effects of AVGs in people with musculoskeletal pathologies, such as knee and hip OA. Accordingly, the purpose is to analyze the effects of an AVG-guided physical exercise protocol adjunct to CPR on functional mobility in older adults with knee and/or hip OA.

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip

Keywords

osteoarhrosis; elderly; exercise training; video games; public health

Outcome Measures

Primary Outcomes (1)

• Change in Functional mobility.

  Timed Up and Go (TUG). Number of seconds required to get up from seated position, walk 3 m, turn, and return to seated position on chair.

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

Secondary Outcomes (14)

• Change in Lower body strength.

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

• Change in Upper body strength.

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

• Change in Aerobic endurance.

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

• Change in Lower body flexibility

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

• Change in Upper body flexibility.

  Five-time points. Baseline (pre-intervention); at week 4 (after ten sessions from baseline); at week 7 (after 20 sessions from baseline); and week 10 (after 30 sessions from baseline). In addition, four weeks after the completion of the intervention.

Study Arms (2)

Experimental group

EXPERIMENTAL

Conventional physical rehabilitation plus Active video games (CPR+AVG)

Other: Conventional physical rehabilitation plus Active video games (CPR+AVG)

Control group

ACTIVE COMPARATOR

Conventional physical rehabilitation alone (CPR)

Other: Conventional physical rehabilitation alone (CPR)

Interventions

Conventional physical rehabilitation plus Active video games (CPR+AVG) OTHER

In each session a routine of conventional physical rehabilitation and active video games is performed. The duration is 10 weeks / 3 sessions per week (30 sessions). CPR+AVG: Consists of conventional exercises (aerobic, muscle strengthening, postural balance and flexibility) added to a set of interactive video games available for the Nintendo Switch console.

Experimental group

Conventional physical rehabilitation alone (CPR) OTHER

In each session a routine of conventional exercises is performed. The duration is 10 weeks / 3 sessions per week (30 sessions). CPR: Conventional exercises (aerobic, muscle strengthening, postural balance and flexibility).

Control group

Eligibility Criteria

• Age: 60 Years - 84 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥60 and ≤84 years.
• Diagnosis of mild or moderate OA of the knee and/or hip.
• Independent walking capacity of at least 15 meters.

You may not qualify if:

• Inability to interact with active video games.
• Undergoing treatment with opioids or other medications with a potential influence on the outcomes of interest.
• \<13 points in the abbreviated version of the Mini-Mental State Examination (MMSE-EFAM).
• OA associated with infectious, autoimmune, fractures or surgery.
• Participate or have participated in another physical-cognitive rehabilitation program during the last 3 months.

Sponsors & Collaborators

• Cristian Alvarez: lead
• National Fund for Research and Development in Health, Chile: collaborator

Study Sites (1)

Centro de Salud Familiar (CESFAM) Lorenzo Arenas

Concepción, Chile

Location

Related Publications (36)

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MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Cristhian Mendoza S., PhD

  Universidad San Sebastian

  STUDY CHAIR

• Claudio Carvajal P., PhD

  Universidad San Sebastian

  STUDY DIRECTOR

• Jorge Fuentes C., PhD

  Universidad Católica del Maule

  STUDY DIRECTOR

• Camila Riquelme B.

  Universidad Andrés Bello

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Investigator: Statistical data analyst.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Proffesor

Model Details: Randomized clinical trial (RCT).

Study Record Dates

• First Submitted: March 15, 2023
• First Posted: May 3, 2023
• Study Start: April 4, 2023
• Primary Completion: March 1, 2024
• Study Completion: March 1, 2024
• Last Updated: March 18, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

CL (1)