MRI Sequence and Imaging Protocol Development
BikeMRI
1 other identifier
observational
200
1 country
1
Brief Summary
The purpose of this study is to develop imaging protocols when using cardiovascular magnetic resonance (CMR) to assess cardiac functions, morphology and tissue characterization. The National Heart Research Institute Singapore (NHRIS) houses two dedicated CMR scanners to support the numerous investigator initiated projects in patients with various cardiac pathologists. By optimizing novel CMR sequences used in these studies, scanning time can be shortened for patients with underlying cardiac diseases.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2016
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2016
CompletedFirst Submitted
Initial submission to the registry
January 31, 2017
CompletedFirst Posted
Study publicly available on registry
February 2, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2022
CompletedMarch 3, 2021
June 1, 2020
6.8 years
January 31, 2017
March 2, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
First occurrence of cardiovascular event
This outcomes are obtained via hospital records or by a phone follow-up
1 day
Study Arms (2)
Healthy Volunteer
Healthy Volunteers will undergo a cardiovascular magnetic resonance imaging scan.
Diseased (Suspected or Known Cardiac Conditions)
Patients will undergo a cardiovascular magnetic resonance imaging scan.
Interventions
Eligibility Criteria
Potential participants will be identified from an existing database of healthy volunteers who had previously participated in the biobank program and indicated interest in future studies. Potential patients are identified from the imaging or admissions databases. The primary physicians of these patients identified will be notified prior to recruitment and the patient will only be recruited if the primary physician is agreeable. Alternatively, other methods of participant identification include co-workers of the department who volunteer themselves and indicate on the Informed Consent Document that their participation was entirely voluntary and not under coercion. Team members of this study are not eligible for participation.
You may qualify if:
- Has no known significant medical history
- Is able to give informed consent
You may not qualify if:
- Has contraindications to CMR implantable devices, cerebral aneutysm clips and cochlear implants
- Has claustrophobia
- Females who are pregnant
- Is unable to comply with study protocols
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Heart Centre Singapore
Singapore, 169609, Singapore
Related Publications (1)
Le TT, Bryant JA, Ting AE, Ho PY, Su B, Teo RC, Gan JS, Chung YC, O'Regan DP, Cook SA, Chin CW. Assessing exercise cardiac reserve using real-time cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2017 Jan 23;19(1):7. doi: 10.1186/s12968-017-0322-1.
PMID: 28110638RESULT
Biospecimen
Blood samples will be collected from all participants before and after the CMR scan.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 31, 2017
First Posted
February 2, 2017
Study Start
March 1, 2016
Primary Completion
December 1, 2022
Study Completion
December 1, 2022
Last Updated
March 3, 2021
Record last verified: 2020-06
Data Sharing
- IPD Sharing
- Will not share