Molecular and Imaging Studies of Cardiovascular Health and Disease
Biobank
1 other identifier
observational
5,000
1 country
1
Brief Summary
Biobank is a program which collects biological samples, health information and imaging data from consented patients and stored them at the core facility. These information would be used to study the molecular, imaging and outcome studies of cardiovascular health and disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2013
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2013
CompletedFirst Submitted
Initial submission to the registry
May 31, 2016
CompletedFirst Posted
Study publicly available on registry
June 17, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2033
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2033
June 17, 2016
July 1, 2013
20 years
May 31, 2016
June 14, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Numbers of genetic variation in genes known to cause inherited cardiac condition and circulating biomarkers which are linked with DNA changes using advanced sequencing and informatics approaches
10 years
Study Arms (5)
Healthy Volunteer
Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement
Dilated Cardiomyopathy
Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement
Hypertrophic cardiomyopathy
Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement
Ischemic heart disease with reduced EF
Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement
Ischemic heart disease with normal EF
Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement
Interventions
For the evaluation of heart function and structure of the cardiovascular system.
It utilizes a scale machine to measure the body fat and skeletal muscle percentage
Eligibility Criteria
Patient will be recruited from primary care clinic and outpatient clinics from the National Heart Centre Singapore. For healthy volunteer, they will be recruited through poster and advertisement.
You may not qualify if:
- Subject aged ≥ 16 years and ≤ 90 years.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Heart Centre Singapore
Singapore, Singapore, 169609, Singapore
Biospecimen
whole blood and serum.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Stuart Cook, MBBS,PhD
National Heart Centre Singapore
Central Study Contacts
Stuart Cook, MBBS, PhD
CONTACT
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 31, 2016
First Posted
June 17, 2016
Study Start
July 1, 2013
Primary Completion (Estimated)
July 1, 2033
Study Completion (Estimated)
July 1, 2033
Last Updated
June 17, 2016
Record last verified: 2013-07
Data Sharing
- IPD Sharing
- Will not share