NCT02984345

Brief Summary

The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Jan 2017

Longer than P75 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 2, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 6, 2016

Completed
2 months until next milestone

Study Start

First participant enrolled

January 26, 2017

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2022

Completed
Last Updated

April 30, 2025

Status Verified

April 1, 2025

Enrollment Period

1.3 years

First QC Date

December 2, 2016

Last Update Submit

April 25, 2025

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

  • Muscle fractional synthetic rate (muscle protein synthesis)

    7.5 hours

Secondary Outcomes (3)

  • Plasma amino acid concentration

    7.5 hours

  • Serum insulin concentration

    7.5 hours

  • Molecular markers of muscle anabolism

    7.5 hours

Study Arms (2)

Mycoprotein beverage

ACTIVE COMPARATOR
Other: Mycoprotein beverage

Milk protein beverage

PLACEBO COMPARATOR
Other: Milk protein beverage

Interventions

Mycoprotein beverageOTHER

Mycoprotein protein beverage

Mycoprotein beverage
Milk protein beverageOTHER

Milk protein beverage

Milk protein beverage

Eligibility Criteria

Age18 Years - 40 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • BMI between 18 and 30 -

You may not qualify if:

  • Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
  • Any diagnosed cardiovascular disease or hypertension.
  • Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
  • Chronic use of any prescribed or over the counter pharmaceuticals.
  • A personal or family history of epilepsy, seizures or schizophrenia.
  • Anyone with previous motor disorders.
  • An allergy to mycoprotein / Quorn, penicillin, or milk.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences

Exeter, Devon, EX1 2LU, United Kingdom

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 2, 2016

First Posted

December 6, 2016

Study Start

January 26, 2017

Primary Completion

May 1, 2018

Study Completion

May 1, 2022

Last Updated

April 30, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations

GB(1)